| DNA methylation dynamics of the human preimplantation embryo ZD Smith, MM Chan, KC Humm, R Karnik, S Mekhoubad, A Regev, ... Nature 511 (7511), 611-615, 2014 | 663 | 2014 |
| Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells J Liao, R Karnik, H Gu, MJ Ziller, K Clement, AM Tsankov, V Akopian, ... Nature Genetics 47 (5), 469-478, 2015 | 551 | 2015 |
| LKB1 loss links serine metabolism to DNA methylation and tumorigenesis F Kottakis, BN Nicolay, A Roumane, R Karnik, H Gu, JM Nagle, ... Nature 539 (7629), 390-395, 2016 | 307 | 2016 |
| Proto-Oncogenic Role of Mutant IDH2 in Leukemia Initiation and Maintenance LM Kats, M Reschke, R Taulli, O Pozdnyakova, K Burgess, P Bhargava, ... Cell Stem Cell, 2014 | 249 | 2014 |
| Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency D Cacchiarelli, C Trapnell, MJ Ziller, M Soumillon, M Cesana, R Karnik, ... Cell 162 (2), 412-424, 2015 | 246 | 2015 |
| Genetic determinants and epigenetic effects of pioneer-factor occupancy J Donaghey, S Thakurela, J Charlton, JS Chen, ZD Smith, H Gu, R Pop, ... Nature Genetics, 1, 2018 | 179 | 2018 |
| X Chromosome Reactivation Dynamics Reveal Stages of Reprogramming to Pluripotency V Pasque, J Tchieu, R Karnik, M Uyeda, AS Dimashkie, D Case, B Papp, ... Cell 159 (7), 1681-1697, 2014 | 122 | 2014 |
| Ground State Conditions Induce Rapid Reorganization of Core Pluripotency Factor Binding before Global Epigenetic Reprogramming C Galonska, MJ Ziller, R Karnik, A Meissner Cell Stem Cell 17 (4), 462-470, 2015 | 121 | 2015 |
| PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells PP Das, DA Hendrix, E Apostolou, AH Buchner, MC Canver, S Beyaz, ... Cell Reports 12 (9), 1456-1470, 2015 | 75 | 2015 |
| Zika virus alters DNA methylation of neural genes in an organoid model of the developing human brain S Janssens, M Schotsaert, R Karnik, V Balasubramaniam, M Dejosez, ... MSystems 3 (1), 10.1128/msystems. 00219-17, 2018 | 51 | 2018 |
| X chromosome dosage influences DNA methylation dynamics during reprogramming to mouse iPSCs V Pasque, R Karnik, C Chronis, P Petrella, J Langerman, G Bonora, ... Stem cell reports 10 (5), 1537-1550, 2018 | 46 | 2018 |
| Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2 A Rajavelu, C Lungu, M Emperle, M Dukatz, A Bröhm, J Broche, I Hanelt, ... Nucleic acids research 46 (17), 9044-9056, 2018 | 44 | 2018 |
| Chromatin-state barriers enforce an irreversible mammalian cell fate decision MA Blanco, DB Sykes, L Gu, M Wu, R Petroni, R Karnik, M Wawer, J Rico, ... Cell Reports 37 (6), 2021 | 35 | 2021 |
| Targets and genomic constraints of ectopic Dnmt3b expression Y Zhang, J Charlton, R Karnik, I Beerman, ZD Smith, H Gu, P Boyle, X Mi, ... eLife 7, e40757, 2018 | 34 | 2018 |
| IRAK4 degrader in hidradenitis suppurativa and atopic dermatitis: a phase 1 trial L Ackerman, G Acloque, S Bacchelli, H Schwartz, BJ Feinstein, ... Nature Medicine 29 (12), 3127-3136, 2023 | 32 | 2023 |
| Browsing (Epi) genomes: A Guide to Data Resources and Epigenome Browsers for Stem Cell Researchers R Karnik, A Meissner Cell Stem Cell 13 (1), 14-21, 2013 | 25 | 2013 |
| Identification of predictive cis-regulatory elements using a discriminative objective function and a dynamic search space R Karnik, MA Beer PloS one 10 (10), e0140557, 2015 | 8 | 2015 |
| Methods and compositions for modulating gene expression LG Lande, DA Berry, R Karnik US Patent 11,624,065, 2023 | 4 | 2023 |
| COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN B (APOB) GENE EXPRESSION VA Patil, JD Farelli, R Karnik, JJ Smith, C Sarisozen, AW Scheidegger, ... US Patent App. 17/701,325, 2022 | 1 | 2022 |
| Compositions and methods for modulating genomic complex integrity index LG Lande, DA Berry, R Karnik US Patent App. 17/754,050, 2022 | 1 | 2022 |
Michael ZillerDepartment of Psychiatry, University of MuensterVerified email at uni-muenster.de
