Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway R Alaaeldin, IAM Abdel-Rahman, HA Hassan, N Youssef, AE Allam, ... Molecules 26 (24), 7629, 2021 | 39 | 2021 |
In vitro inhibition and molecular docking of a new ciprofloxacin‐chalcone against SARS‐CoV‐2 main protease R Alaaeldin, M Mustafa, GEDA Abuo‐Rahma, M Fathy Fundamental & Clinical Pharmacology 36 (1), 160-170, 2022 | 33 | 2022 |
Cell Cycle Arrest and Apoptotic Effect of 7-(4-(N-substituted carbamoylmethyl) piperazin-1-yl) Ciprofloxacin-derivative on HCT 116 and A549 Cancer Cells R Alaaeldin, MH Nazmy, M Abdel-Aziz, GEDA Abuo-Rahma, M Fathy Anticancer research 40 (5), 2739-2749, 2020 | 24 | 2020 |
Inhibition of NF-kB/IL-6/JAK2/STAT3 pathway and epithelial-mesenchymal transition in breast cancer cells by azilsartan R Alaaeldin, FEM Ali, AA Bekhit, QL Zhao, M Fathy Molecules 27 (22), 7825, 2022 | 23 | 2022 |
Modulation of apoptosis and epithelial-Mesenchymal transition E-cadherin/TGF-β/Snail/TWIST pathways by a new ciprofloxacin chalcone in breast cancer cells R Alaaeldin, GEDA Abuo-Rahma, QL Zhao, M Fathy Anticancer Research 41 (5), 2383-2395, 2021 | 23 | 2021 |
A New EGFR Inhibitor from Ficus benghalensis Exerted Potential Anti-Inflammatory Activity via Akt/PI3K Pathway Inhibition R Alaaeldin, HA Hassan, IM Abdel-Rahman, RH Mohyeldin, N Youssef, ... Current Issues in Molecular Biology 44 (7), 2967-2981, 2022 | 19 | 2022 |
Anti-Alzheimer chemical constituents of Morus macroura Miq.: chemical profiling, in silico and in vitro investigations SS El-Hawary, AM Sayed, MY Issa, HS Ebrahim, R Alaaeldin, ... Food & Function 12 (17), 8078-8089, 2021 | 18 | 2021 |
Hepatoprotective potential of gabapentin in cecal ligation and puncture-induced sepsis; targeting oxidative stress, apoptosis, and NF-kB/MAPK signaling pathways M Abdelnaser, R Alaaeldin, ME Attya, M Fathy Life Sciences 320, 121562, 2023 | 12 | 2023 |
Metformin-loaded ethosomes with promoted anti-proliferative activity in melanoma cell line B16, and wound healing aptitude: Development, characterization and in vivo evaluation S Magdy, E Alaaeldin, Z Fathalla, R Alaaeldin, M Elrehany, EA Saber, ... International Journal of Pharmaceutics 621, 121781, 2022 | 12 | 2022 |
The Protective and Therapeutic Anti-Alzheimer Potential of Olea europaea L. cv. Picual: An In Silico and In Vivo Study AA Bagalagel, SS El-Hawary, R Alaaeldin, AH Elmaidomy, FH Altemani, ... Metabolites 12 (12), 1178, 2022 | 11 | 2022 |
Dual topoisomerase I/II inhibition-induced apoptosis and necro-apoptosis in cancer cells by a novel ciprofloxacin derivative via RIPK1/RIPK3/MLKL activation R Alaaeldin, IM Abdel-Rahman, FEM Ali, AA Bekhit, EY Elhamadany, ... Molecules 27 (22), 7993, 2022 | 11 | 2022 |
Azilsartan modulates HMGB1/NF-κB/p38/ERK1/2/JNK and apoptosis pathways during renal ischemia reperfusion injury R Alaaeldin, SM Bakkar, RH Mohyeldin, FEM Ali, NMR Abdel-Maqsoud, ... Cells 12 (1), 185, 2023 | 8 | 2023 |
Modulating Nrf-2/HO-1, apoptosis and oxidative stress signaling pathways by gabapentin ameliorates sepsis-induced acute kidney injury M Abdelnaser, R Alaaeldin, ME Attya, M Fathy Naunyn-schmiedeberg's Archives of Pharmacology 397 (2), 947-958, 2024 | 7 | 2024 |
Vincamine Ameliorates Epithelial-Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis in Rats; Targeting TGF-β/MAPK/Snai1 Pathway R Alaaeldin, RH Mohyeldin, AA Bekhit, W Gomaa, QL Zhao, M Fathy Molecules 28 (12), 4665, 2023 | 6 | 2023 |
Bone marrow-derived mesenchymal stem cells modulate apoptosis and angiogenesis in cyclophosphamide-induced spleen injury in rats G Abdelrahman Bakhaat, EK Rashwan, R Alaaeldin, M Fathy Egyptian Journal of Histology, 2022 | 5 | 2022 |
Bioactives and functional food ingredients with promising potential for the management of cerebral and myocardial ischemia: a comprehensive mechanistic review EM Zahran, AM Sayed, R Alaaeldin, MA Elrehany, AR Khattab, ... Food & Function 13 (13), 6859-6874, 2022 | 5 | 2022 |
LCZ696 attenuates sepsis-induced liver dysfunction in rats; the role of oxidative stress, apoptosis, and JNK1/2-P38 signaling pathways RH Mohyeldin, R Alaaeldin, EE Sharata, ME Attya, EY Elhamadany, ... Life Sciences 334, 122210, 2023 | 3 | 2023 |
Anti-Alzheimer Potential of a New (+)-Pinitol Glycoside Isolated from Tamarindus indica Pulp: In Vivo and In Silico Evaluations EM Mohamed, A H. Elmaidomy, R Alaaeldin, F Alsenani, FH Altemani, ... Metabolites 13 (6), 732, 2023 | 3 | 2023 |
Solulan C24-and bile salts-modified niosomes for new ciprofloxacin mannich base for combatting Pseudomonas-infected corneal ulcer in rabbits SA Mohamed, MA Abdelgawad, R Alaaeldin, Z Fathalla, H Moharram, ... Pharmaceuticals 15 (1), 44, 2021 | 3 | 2021 |
Plant and endophyte-derived anti-hyperlipidemics: A comprehensive review with in silico studies NH Shady, A Zayed, R Alaaeldin, M Hisham, M Gawesh, R Mohammed, ... South African Journal of Botany 163, 105-120, 2023 | | 2023 |