| Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974 J Liu, S Pan, MH Hsieh, N Ng, F Sun, T Wang, S Kasibhatla, AG Schuller, ... Proceedings of the National Academy of Sciences 110 (50), 20224-20229, 2013 | 822 | 2013 |
| Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors J Zhang, FJ Adrián, W Jahnke, SW Cowan-Jacob, AG Li, RE Iacob, T Sim, ... Nature 463 (7280), 501-506, 2010 | 679 | 2010 |
| Induction of sonic hedgehog mediators by transforming growth factor-β: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo S Dennler, J André, I Alexaki, A Li, T Magnaldo, P Ten Dijke, XJ Wang, ... Cancer research 67 (14), 6981-6986, 2007 | 448 | 2007 |
| Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-N2-(2-isopropoxy-5 … TH Marsilje, W Pei, B Chen, W Lu, T Uno, Y Jin, T Jiang, S Kim, N Li, ... Journal of medicinal chemistry 56 (14), 5675-5690, 2013 | 441 | 2013 |
| Distinct mechanisms of TGF-β1–mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis G Han, SL Lu, AG Li, W He, CL Corless, M Kulesz-Martin, XJ Wang The Journal of clinical investigation 115 (7), 1714-1723, 2005 | 309 | 2005 |
| Signaling mechanism of TGF-β1 in prevention of renal inflammation: role of Smad7 W Wang, XR Huang, AG Li, F Liu, JH Li, LD Truong, XJ Wang, HY Lan Journal of the American Society of Nephrology 16 (5), 1371-1383, 2005 | 304 | 2005 |
| Role of TGFβ-mediated inflammation in cutaneous wound healing XJ Wang, G Han, P Owens, Y Siddiqui, AG Li Journal of Investigative Dermatology Symposium Proceedings 11 (1), 112-117, 2006 | 284 | 2006 |
| Latent TGFβ1 overexpression in keratinocytes results in a severe psoriasis‐like skin disorder AG Li, D Wang, XH Feng, XJ Wang The EMBO journal 23 (8), 1770-1781, 2004 | 270 | 2004 |
| Overexpression of transforming growth factor β1 in head and neck epithelia results in inflammation, angiogenesis, and epithelial hyperproliferation SL Lu, D Reh, AG Li, J Woods, CL Corless, M Kulesz-Martin, XJ Wang Cancer research 64 (13), 4405-4410, 2004 | 255 | 2004 |
| Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression KE Hoot, J Lighthall, G Han, SL Lu, A Li, W Ju, M Kulesz-Martin, ... The Journal of clinical investigation 118 (8), 2722-2732, 2008 | 249 | 2008 |
| Loss of transforming growth factor-β type II receptor promotes metastatic head-and-neck squamous cell carcinoma SL Lu, H Herrington, D Reh, S Weber, S Bornstein, D Wang, AG Li, ... Genes & development 20 (10), 1331-1342, 2006 | 236 | 2006 |
| Loss of transforming growth factor-β type II receptor promotes metastatic head-and-neck squamous cell carcinoma SL Lu, H Herrington, D Reh, S Weber, S Bornstein, D Wang, AG Li, ... Genes & development 20 (10), 1331-1342, 2006 | 236 | 2006 |
| Smad7-induced β-catenin degradation alters epidermal appendage development G Han, AG Li, YY Liang, P Owens, W He, S Lu, Y Yoshimatsu, D Wang, ... Developmental cell 11 (3), 301-312, 2006 | 182 | 2006 |
| Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2 S Hong, S Lim, AG Li, C Lee, YS Lee, EK Lee, SH Park, XJ Wang, SJ Kim Nature immunology 8 (5), 504-513, 2007 | 170 | 2007 |
| Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues W He, AG Li, D Wang, S Han, B Zheng, MJ Goumans, P Ten Dijke, ... The EMBO journal, 2002 | 138 | 2002 |
| Hair follicle defects and squamous cell carcinoma formation in Smad4 conditional knockout mouse skin W Qiao, AG Li, P Owens, X Xu, XJ Wang, CX Deng Oncogene 25 (2), 207-217, 2006 | 119 | 2006 |
| A role for TGFβ signaling in the pathogenesis of psoriasis G Han, CA Williams, K Salter, PJ Garl, AG Li, XJ Wang Journal of investigative dermatology 130 (2), 371-377, 2010 | 112 | 2010 |
| Retinoic acid induces down-regulation of several growth factors and proto-oncogenes in a human embryonal cancer cell line. WH Miller Jr, D Moy, A Li, JF Grippo, E Dmitrovsky Oncogene 5 (4), 511-517, 1990 | 105 | 1990 |
| DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2 H Lopez-Bertoni, B Lal, A Li, M Caplan, H Guerrero-Cazares, CG Eberhart, ... Oncogene 34 (30), 3994-4004, 2015 | 104 | 2015 |
| Essential roles of BMPR‐IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis K Ming Kwan, AG Li, XJ Wang, W Wurst, RR Behringer Genesis 39 (1), 10-25, 2004 | 94 | 2004 |
Peter ten DijkeVerified email at lumc.nl
