| Immunomodulatory drugs disrupt the cereblon–CD147–MCT1 axis to exert antitumor activity and teratogenicity R Eichner, M Heider, V Fernández-Sáiz, F van Bebber, AK Garz, ... Nature medicine 22 (7), 735-743, 2016 | 178 | 2016 |
| Imbalances in p97 co‐factor interactions in human proteinopathy V Fernández‐Sáiz, A Buchberger EMBO reports 11 (6), 479-485, 2010 | 128 | 2010 |
| SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma V Fernández-Sáiz, BS Targosz, S Lemeer, R Eichner, C Langer, ... Nature cell biology 15 (1), 72-81, 2013 | 106 | 2013 |
| Interdomain interaction through helices A and B of DnaK peptide binding domain F Moro, V Fernández, A Muga FEBS letters 533, 119-123, 2003 | 89 | 2003 |
| Cellular functions of Ufd2 and Ufd3 in proteasomal protein degradation depend on Cdc48 binding S Böhm, G Lamberti, V Fernández-Sáiz, C Stapf, A Buchberger Molecular and cellular biology 31 (7), 1528-1539, 2011 | 65 | 2011 |
| Disruption of the PRKCD–FBXO25–HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis U Baumann, V Fernández-Sáiz, M Rudelius, S Lemeer, R Rad, AM Knorn, ... Nature medicine 20 (12), 1401-1409, 2014 | 62 | 2014 |
| DnaJ recruits DnaK to protein aggregates SP Acebron, V Fernandez-Saiz, SG Taneva, F Moro, A Muga Journal of biological chemistry 283 (3), 1381-1390, 2008 | 60 | 2008 |
| USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B‐cell lymphoma K Engel, M Rudelius, J Slawska, L Jacobs, B Ahangarian Abhari, ... EMBO molecular medicine 8 (8), 851-862, 2016 | 58 | 2016 |
| The lid subdomain of DnaK is required for the stabilization of the substrate-binding site F Moro, V Fernández-Sáiz, A Muga Journal of Biological Chemistry 279 (19), 19600-19606, 2004 | 58 | 2004 |
| UBXD1 binds p97 through two independent binding sites M Kern, V Fernandez-Sáiz, Z Schäfer, A Buchberger Biochemical and biophysical research communications 380 (2), 303-307, 2009 | 49 | 2009 |
| Ionic contacts at DnaK substrate binding domain involved in the allosteric regulation of lid dynamics V Fernández-Sáiz, F Moro, JM Arizmendi, SP Acebrón, A Muga Journal of biological chemistry 281 (11), 7479-7488, 2006 | 47 | 2006 |
| α-Radioimmunotherapy with 213Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma K Teiluf, C Seidl, B Blechert, FC Gaertner, KP Gilbertz, V Fernandez, ... Oncotarget 6 (7), 4692, 2015 | 42 | 2015 |
| The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma M Heider, R Eichner, J Stroh, V Morath, A Kuisl, J Zecha, J Lawatscheck, ... Molecular cell 81 (6), 1170-1186. e10, 2021 | 39 | 2021 |
| USP42 protects ZNRF3/RNF43 from R‐spondin‐dependent clearance and inhibits Wnt signalling N Giebel, A de Jaime‐Soguero, A García del Arco, JJM Landry, M Tietje, ... EMBO reports 22 (5), e51415, 2021 | 31 | 2021 |
| The allosteric transition in DnaK probed by infrared difference spectroscopy. Concerted ATP‐induced rearrangement of the substrate binding domain F Moro, V Fernández‐Sáiz, A Muga Protein science 15 (2), 223-233, 2006 | 30 | 2006 |
| Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival M Dietachmayr, A Rathakrishnan, O Karpiuk, F von Zweydorf, T Engleitner, ... Nature communications 11 (1), 1268, 2020 | 28 | 2020 |
| Conformational properties of bacterial DnaK and yeast mitochondrial Hsp70: Role of the divergent C‐terminal α‐helical subdomain F Moro, V Fernández‐Sáiz, O Slutsky, A Azem, A Muga The FEBS journal 272 (12), 3184-3196, 2005 | 21 | 2005 |
| Cross talk networks of mammalian target of rapamycin signaling with the ubiquitin proteasome system and their clinical implications in multiple myeloma R Eichner, V Fernández-Sáiz, BS Targosz, F Bassermann International review of cell and molecular biology 343, 219-297, 2019 | 18 | 2019 |
| c-Rel gain in B cells drives germinal center reactions and autoantibody production M Kober-Hasslacher, H Oh-Strauß, D Kumar, V Soberon, C Diehl, M Lech, ... The Journal of Clinical Investigation 130 (6), 3270-3286, 2020 | 17 | 2020 |
| AGR2-dependent nuclear import of RNA polymerase II constitutes a specific target of pancreatic ductal adenocarcinoma in the context of wild-type p53 Z Zhang, H Li, Y Deng, K Schuck, S Raulefs, N Maeritz, Y Yu, T Hechler, ... Gastroenterology 161 (5), 1601-1614. e23, 2021 | 13 | 2021 |
