Oxysterols and atherosclerosis AJ Brown, W Jessup Atherosclerosis 142 (1), 1-28, 1999 | 1098 | 1999 |
ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-I IC Gelissen, M Harris, KA Rye, C Quinn, AJ Brown, M Kockx, S Cartland, ... Arteriosclerosis, thrombosis, and vascular biology 26 (3), 534-540, 2006 | 546 | 2006 |
Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism AJ Brown, L Sun, JD Feramisco, MS Brown, JL Goldstein Molecular cell 10 (2), 237-245, 2002 | 514 | 2002 |
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast W Fei, G Shui, B Gaeta, X Du, L Kuerschner, P Li, AJ Brown, MR Wenk, ... Journal of Cell Biology 180 (3), 473-482, 2008 | 502 | 2008 |
Controlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) LJ Sharpe, AJ Brown Journal of Biological Chemistry 288 (26), 18707-18715, 2013 | 396 | 2013 |
A role for phosphatidic acid in the formation of “supersized” lipid droplets W Fei, G Shui, Y Zhang, N Krahmer, C Ferguson, TS Kapterian, RC Lin, ... PLoS genetics 7 (7), e1002201, 2011 | 368 | 2011 |
The Akt–SREBP nexus: cell signaling meets lipid metabolism JR Krycer, LJ Sharpe, W Luu, AJ Brown Trends in Endocrinology & Metabolism 21 (5), 268-276, 2010 | 358 | 2010 |
Oxysterols: sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis AJ Brown, W Jessup Molecular aspects of medicine 30 (3), 111-122, 2009 | 349 | 2009 |
A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking X Du, J Kumar, C Ferguson, TA Schulz, YS Ong, W Hong, WA Prinz, ... Journal of Cell Biology 192 (1), 121-135, 2011 | 339 | 2011 |
Cholesterol-dependent degradation of squalene monooxygenase, a control point in cholesterol synthesis beyond HMG-CoA reductase S Gill, J Stevenson, I Kristiana, AJ Brown Cell metabolism 13 (3), 260-273, 2011 | 308 | 2011 |
7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque. AJ Brown, SL Leong, RT Dean, W Jessup Journal of lipid research 38 (9), 1730-1745, 1997 | 291 | 1997 |
Persistent changes in the fatty acid composition of erythrocyte membranes after moderate intake of n− 3 polyunsaturated fatty acids: study design implications AJ Brown, E Pang, DC Roberts The American journal of clinical nutrition 54 (4), 668-673, 1991 | 291 | 1991 |
Sterol regulators of cholesterol homeostasis and beyond: the oxysterol hypothesis revisited and revised S Gill, R Chow, AJ Brown Progress in lipid research 47 (6), 391-404, 2008 | 268 | 2008 |
Free and esterified oxysterol: formation during copper-oxidation of low density lipoprotein and uptake by macrophages. AJ Brown, RT Dean, W Jessup Journal of lipid research 37 (2), 320-335, 1996 | 202 | 1996 |
Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis JM Upston, X Niu, AJ Brown, R Mashima, H Wang, R Senthilmohan, ... The American journal of pathology 160 (2), 701-710, 2002 | 192 | 2002 |
Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: a link between a key cell proliferative pathway and membrane synthesis X Du, I Kristiana, J Wong, AJ Brown Molecular biology of the cell 17 (6), 2735-2745, 2006 | 191 | 2006 |
Dietary cosupplementation with vitamin E and coenzyme Q10 inhibits atherosclerosis in apolipoprotein E gene knockout mice SR Thomas, SB Leichtweis, K Pettersson, KD Croft, TA Mori, AJ Brown, ... Arteriosclerosis, thrombosis, and vascular biology 21 (4), 585-593, 2001 | 191 | 2001 |
Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux J Wong, CM Quinn, AJ Brown Arteriosclerosis, thrombosis, and vascular biology 24 (12), 2365-2371, 2004 | 182 | 2004 |
ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P2) and regulate its level at the plasma membrane R Ghai, X Du, H Wang, J Dong, C Ferguson, AJ Brown, RG Parton, ... Nature communications 8 (1), 757, 2017 | 179 | 2017 |
SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR J Wong, CM Quinn, AJ Brown Biochemical Journal 400 (3), 485-491, 2006 | 171 | 2006 |