Nonviral gene delivery with cationic glycopolymers C Van Bruggen, JK Hexum, Z Tan, RJ Dalal, TM Reineke Accounts of Chemical Research 52 (5), 1347-1358, 2019 | 124 | 2019 |
Polycation architecture and assembly direct successful gene delivery: micelleplexes outperform polyplexes via optimal DNA packaging Z Tan, Y Jiang, W Zhang, L Karls, TP Lodge, TM Reineke Journal of the American Chemical Society 141 (40), 15804-15817, 2019 | 77 | 2019 |
Efficient polymer-mediated delivery of gene-editing ribonucleoprotein payloads through combinatorial design, parallelized experimentation, and machine learning R Kumar, N Le, Z Tan, ME Brown, S Jiang, TM Reineke ACS nano 14 (12), 17626-17639, 2020 | 71 | 2020 |
Block polymer micelles enable CRISPR/Cas9 ribonucleoprotein delivery: physicochemical properties affect packaging mechanisms and gene editing efficiency Z Tan, Y Jiang, MS Ganewatta, R Kumar, A Keith, K Twaroski, T Pengo, ... Macromolecules 52 (21), 8197-8206, 2019 | 51 | 2019 |
Cell Penetrating Polymers Containing Guanidinium Trigger Apoptosis in Human Hepatocellular Carcinoma Cells unless Conjugated to a Targeting N-Acetyl … Z Tan, YK Dhande, TM Reineke Bioconjugate Chemistry 28 (12), 2985-2997, 2017 | 24 | 2017 |
Cationic Polymers Enable Internalization of Negatively Charged Chemical Probes into Bacteria HK Lembke, A Espinasse, MG Hanson, CJ Grimme, Z Tan, TM Reineke, ... ACS Chemical Biology 18 (9), 2063-2072, 2023 | | 2023 |
Copolymers for intracellular therapeutic nucleic acid payload delivery T Reineke, N Le, Z Tan, R Kumar US Patent App. 18/000,258, 2023 | | 2023 |
Cationic block polymer micelles for delivery of biological agents T Reineke, Z Tan, Y Jiang, MS Ganewatta, TP Lodge US Patent 11,564,884, 2023 | | 2023 |
Data-Driven Discovery of Polymeric Vehicles for Gene Editing: Serendipity-Inspired Design Directions. R Kumar, N Le, Z Tan, TM Reineke 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
Accelerating the Discovery of Polymeric Vehicles for Gene Editing through Combinatorial Synthesis and Statistical Learning R Kumar, N Le, Z Tan, TM Reineke 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
Development of Polymeric Vehicles for Gene Delivery Using High-Throughput Experimentation and Statistical Learning R Kumar, N Le, Z Tan, TM Reineke 2019 AIChE Annual Meeting, 2019 | | 2019 |
Development of polymeric biomaterials using high-throughput experimentation and statistical learning R Kumar, N Le, Z Tan, T Reineke ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
Cationic Polymers and Polymeric Micelles as Plasmid DNA and CRISPR-Cas9 Ribonucleoprotein Delivery Vehicles Z Tan University of Minnesota, 2019 | | 2019 |
Guanidium-based cell penetrating polymers as delivery agents trigger apoptosis in HepG2 cells but can be alleviated by conjugating to hydrophilic block Z Tan, Y Dhande, T Reineke ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
Supporting information Efficient polymer-mediated delivery of ribonucleoprotein payloads through combinatorial design & parallelized experimentation. R Kumar, N Le, Z Tan, ME Brown, S Jiang, TM Reineke | | |