Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees F Stutzmann, K Tan, V Vatin, C Dina, B Jouret, J Tichet, B Balkau, ... Diabetes 57 (9), 2511-2518, 2008 | 297 | 2008 |
MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains KO Tan, KML Tan, SL Chan, KSY Yee, M Bévort, KC Ang, CY Victor Journal of Biological Chemistry 276 (4), 2802-2807, 2001 | 169 | 2001 |
A quantitative trait locus on chromosome 18q for physical activity and dietary intake in Hispanic children G Cai, SA Cole, N Butte, C Bacino, V Diego, K Tan, HH Göring, S O'rahilly, ... Obesity 14 (9), 1596-1604, 2006 | 151 | 2006 |
Functional characterization and structural modeling of obesity associated mutations in the melanocortin 4 receptor K Tan, ID Pogozheva, GSH Yeo, D Hadaschik, JM Keogh, ... Endocrinology 150 (1), 114-125, 2009 | 99 | 2009 |
Analysis of genetic variation in Akt2/PKB-β in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes K Tan, WA Kimber, J Luan, MA Soos, RK Semple, NJ Wareham, ... Diabetes 56 (3), 714-719, 2007 | 81 | 2007 |
Prevalence and functionality of paucimorphic and private MC4R mutations in a large, unselected European British population, scanned by meltMADGE KK Alharbi, E Spanakis, K Tan, MJ Smith, MA Aldahmesh, SD O'Dell, ... Human mutation 28 (3), 294-302, 2007 | 77 | 2007 |
A novel BH3-like domain in BID is required for intramolecular interaction and autoinhibition of pro-apoptotic activity KO Tan, KML Tan, CY Victor Journal of Biological Chemistry 274 (34), 23687-23690, 1999 | 74 | 1999 |
The Caenorhabditis elegansSex-determining Protein FEM-2 and Its Human Homologue, hFEM-2, Are Ca2+/Calmodulin-dependent Protein Kinase Phosphatases That Promote Apoptosis KML Tan, SL Chan, KO Tan, CY Victor Journal of Biological Chemistry 276 (47), 44193-44202, 2001 | 66 | 2001 |
Myo-Inositol, Probiotics, and Micronutrient Supplementation From Preconception for Glycemia in Pregnancy: NiPPeR International Multicenter Double-Blind … KM Godfrey, SJ Barton, S El-Heis, T Kenealy, H Nield, PN Baker, ... Diabetes Care 44 (5), 1091-1099, 2021 | 47 | 2021 |
Carnosine and anserine as modulators of neutrophil function KML Tan, JK Candlish Clinical & Laboratory Haematology 20 (4), 239-244, 1998 | 46 | 1998 |
Cohort profile: Singapore preconception study of long-term maternal and child outcomes (S-PRESTO) EXL Loo, SE Soh, SL Loy, S Ng, MT Tint, SY Chan, JY Huang, F Yap, ... European journal of epidemiology 36, 129-142, 2021 | 45 | 2021 |
CYP2C19 and PON1 polymorphisms regulating clopidogrel bioactivation in Chinese, Malay and Indian subjects MY Chan, K Tan, HC Tan, PT Huan, B Li, QH Phua, HK Lee, CH Lee, ... Pharmacogenomics 13 (5), 533-542, 2012 | 44 | 2012 |
Prospective validation of% p2PSA and the Prostate Health Index, in prostate cancer detection in initial prostate biopsies of Asian men, with total PSA 4–10 ng ml− 1 LGL Tan, YK Tan, BC Tai, KML Tan, V Gauhar, HY Tiong, RCW Hawkins, ... Asian journal of andrology 19 (3), 286-290, 2017 | 42 | 2017 |
The Caenorhabditis elegans sex determination protein FEM-1 is a CED-3 substrate that associates with CED-4 and mediates apoptosis in mammalian cells SL Chan, KSY Yee, KML Tan, CY Victor Journal of Biological Chemistry 275 (24), 17925-17928, 2000 | 40 | 2000 |
Longitudinal monitoring reveals dynamic changes in circulating tumor cells (CTCs) and CTC-associated miRNAs in response to chemotherapy in metastatic colorectal cancer patients K Tan, SM Leong, Z Kee, PV Caramat, J Teo, MVM Blanco, ESC Koay, ... Cancer Letters 423, 1-8, 2018 | 37 | 2018 |
Biomarkers in cardiorenal syndromes K Tan, SK Sethi Translational Research 164 (2), 122-134, 2014 | 36 | 2014 |
Comparison of the Elecsys PTH (1–84) Assay with Four Contemporary Second Generation Intact PTH Assays and Association with Other Biomarkers in Chronic Kidney Disease Patients K Tan, L Ong, SK Sethi, S Saw Clinical biochemistry, 2013 | 35 | 2013 |
Mismatch between poor fetal growth and rapid postnatal weight gain in the first 2 years of life is associated with higher blood pressure and insulin resistance without … YY Ong, SA Sadananthan, IM Aris, MT Tint, WL Yuan, JY Huang, ... International journal of epidemiology 49 (5), 1591-1603, 2020 | 30 | 2020 |
Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance KG Mountjoy, A Caron, K Hubbard, A Shome, AC Grey, B Sun, S Bould, ... Molecular metabolism 9, 207-216, 2018 | 26 | 2018 |
Targeted next-generation sequencing of the ATP7B gene for molecular diagnosis of Wilson disease KS Poon, KML Tan, ESC Koay Clinical biochemistry 49 (1-2), 166-171, 2016 | 26 | 2016 |