Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease F Fattahi, JA Steinbeck, S Kriks, J Tchieu, B Zimmer, S Kishinevsky, ... Nature 531 (7592), 105-109, 2016 | 309 | 2016 |
Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression G Lee, CN Ramirez, H Kim, N Zeltner, B Liu, C Radu, B Bhinder, YJ Kim, ... Nature biotechnology 30 (12), 1244-1248, 2012 | 253 | 2012 |
Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells Y Qi, XJ Zhang, N Renier, Z Wu, T Atkin, Z Sun, MZ Ozair, J Tchieu, ... Nature biotechnology 35 (2), 154-163, 2017 | 232 | 2017 |
A modular platform for differentiation of human PSCs into all major ectodermal lineages J Tchieu, B Zimmer, F Fattahi, S Amin, N Zeltner, S Chen, L Studer Cell stem cell 21 (3), 399-410. e7, 2017 | 198 | 2017 |
Pluripotent stem cells in neuropsychiatric disorders MA Soliman, F Aboharb, N Zeltner, L Studer Molecular psychiatry 22 (9), 1241-1249, 2017 | 134 | 2017 |
Site-specific integration of adeno-associated virus involves partial duplication of the target locus E Henckaerts, N Dutheil, N Zeltner, S Kattman, E Kohlbrenner, P Ward, ... Proceedings of the National Academy of Sciences 106 (18), 7571-7576, 2009 | 94 | 2009 |
Pluripotent stem cell-based disease modeling: current hurdles and future promise N Zeltner, L Studer Current opinion in cell biology 37, 102-110, 2015 | 77 | 2015 |
Near-perfect infectivity of wild-type AAV as benchmark for infectivity of recombinant AAV vectors N Zeltner, E Kohlbrenner, N Clément, T Weber, RM Linden Gene therapy 17 (7), 872-879, 2010 | 75 | 2010 |
Capturing the biology of disease severity in a PSC-based model of familial dysautonomia N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, ... Nature medicine 22 (12), 1421-1427, 2016 | 63 | 2016 |
A multiplex human pluripotent stem cell platform defines molecular and functional subclasses of autism-related genes GY Cederquist, J Tchieu, SJ Callahan, K Ramnarine, S Ryan, C Zhang, ... Cell stem cell 27 (1), 35-49. e6, 2020 | 60 | 2020 |
Feeder-free derivation of neural crest progenitor cells from human pluripotent stem cells N Zeltner, FG Lafaille, F Fattahi, L Studer JoVE (Journal of Visualized Experiments), e51609, 2014 | 32 | 2014 |
Derivation of peripheral nociceptive, mechanoreceptive, and proprioceptive sensory neurons from the same culture of human pluripotent stem cells K Saito-Diaz, JR Street, H Ulrichs, N Zeltner Stem Cell Reports 16 (3), 446-457, 2021 | 28 | 2021 |
Male age, mating probability and mating costs in the fly Sepsis cynipsea OY Martin, RR Leugger, N Zeltner, DJ Hosken Evolutionary Ecology Research 5 (1), 119-129, 2003 | 24 | 2003 |
Induced pluripotent stem cells for disease modeling, cell therapy and drug discovery in genetic autonomic disorders: a review K Saito-Diaz, N Zeltner Clinical Autonomic Research 29, 367-384, 2019 | 20 | 2019 |
Autonomic neurons with sympathetic character derived from human pluripotent stem cells K Saito‐Diaz, HF Wu, N Zeltner Current Protocols in Stem Cell Biology 49 (1), e78, 2019 | 15 | 2019 |
Efficient differentiation of postganglionic sympathetic neurons using human pluripotent stem cells under feeder-free and chemically defined culture conditions HF Wu, N Zeltner JoVE (Journal of Visualized Experiments), e60843, 2020 | 13 | 2020 |
Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models HF Wu, W Yu, K Saito-Diaz, CW Huang, J Carey, F Lefcort, GW Hart, ... Nature Communications 13 (1), 7032, 2022 | 7 | 2022 |
Overview of Methods to Differentiate Sympathetic Neurons from Human Pluripotent Stem Cells HF Wu, N Zeltner Current Protocols in Stem Cell Biology 50 (1), e92, 2019 | 7 | 2019 |
Synthetic heparan sulfate hydrogels regulate neurotrophic factor signaling and neuronal network activity CFV Latchoumane, P Chopra, L Sun, A Ahmed, F Palmieri, HF Wu, ... ACS applied materials & interfaces 14 (25), 28476-28488, 2022 | 6 | 2022 |
Low glucose induced Alzheimer's disease‐like biochemical changes in human induced pluripotent stem cell‐derived neurons is due to dysregulated O‐GlcNAcylation CW Huang, NC Rust, HF Wu, A Yin, N Zeltner, H Yin, GW Hart Alzheimer's & Dementia 19 (11), 4872-4885, 2023 | 4 | 2023 |