| High-content screening: a new approach to easing key bottlenecks in the drug discovery process KA Giuliano, RL DeBiasio, RT Dunlay, A Gough, JM Volosky, J Zock, ... SLAS Discovery 2 (4), 249-259, 1997 | 316 | 1997 |
| Chromatin fibers are left-handed double helices with diameter and mass per unit length that depend on linker length SP Williams, BD Athey, LJ Muglia, RS Schappe, AH Gough, JP Langmore Biophysical journal 49 (1), 233-248, 1986 | 306 | 1986 |
| Characterization and Quantitation of NF-κB Nuclear Translocation Induced by Interleukin-1 and Tumor Necrosis Factor-α: development and use of a high capacity fluorescence … GJF Ding, PA Fischer, RC Boltz, JA Schmidt, JJ Colaianne, A Gough, ... Journal of Biological Chemistry 273 (44), 28897-28905, 1998 | 277 | 1998 |
| Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle L Vernetti, A Gough, N Baetz, S Blutt, JR Broughman, JA Brown, ... Scientific reports 7 (1), 42296, 2017 | 247 | 2017 |
| A human liver microphysiology platform for investigating physiology, drug safety, and disease models LA Vernetti, N Senutovitch, R Boltz, R DeBiasio, T Ying Shun, A Gough, ... Experimental biology and medicine 241 (1), 101-114, 2016 | 229 | 2016 |
| In vitro platforms for evaluating liver toxicity SS Bale, L Vernetti, N Senutovitch, R Jindal, M Hegde, A Gough, ... Experimental biology and medicine 239 (9), 1180-1191, 2014 | 191 | 2014 |
| Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems FT Lee-Montiel, SM George, AH Gough, AD Sharma, J Wu, R DeBiasio, ... Experimental Biology and Medicine 242 (16), 1617-1632, 2017 | 133 | 2017 |
| System for cell-based screening RT Dunlay, DL Taylor, AH Gough, KA Giuliano US Patent 6,727,071, 2004 | 132 | 2004 |
| Fluorescence anisotropy imaging microscopy maps calmodulin binding during cellular contraction and locomotion. AH Gough, DL Taylor The Journal of cell biology 121 (5), 1095-1107, 1993 | 129 | 1993 |
| A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX X Li, SM George, L Vernetti, AH Gough, DL Taylor Lab on a Chip 18 (17), 2614-2631, 2018 | 111 | 2018 |
| A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate® KM Bircsak, R DeBiasio, M Miedel, A Alsebahi, R Reddinger, A Saleh, ... Toxicology 450, 152667, 2021 | 104 | 2021 |
| Multimode light microscopy and the dynamics of molecules, cells, and tissues DL Farkas, G Baxter, RL DeBiasio, A Gough, MA Nederlof, D Pane, ... Annual review of physiology 55 (1), 785-817, 1993 | 100 | 1993 |
| Machine readable storage media for detecting distribution of macromolecules between nucleus and cytoplasm in cells RT Dunlay, DL Taylor, AH Gough, KA Giuliano US Patent 6,671,624, 2003 | 85 | 2003 |
| Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems A Soto-Gutierrez, A Gough, LA Vernetti, DL Taylor, SP Monga Experimental Biology and Medicine 242 (16), 1605-1616, 2017 | 80 | 2017 |
| Biologically relevant heterogeneity: metrics and practical insights A Gough, AM Stern, J Maier, T Lezon, TY Shun, C Chennubhotla, ... Slas Discovery: Advancing Life Sciences R&D 22 (3), 213-237, 2017 | 77 | 2017 |
| Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans A Bhushan, N Senutovitch, SS Bale, WJ McCarty, M Hegde, R Jindal, ... Stem cell research & therapy 4, 1-6, 2013 | 76 | 2013 |
| System for cell-based screening RA Rubin, KA Giuliano, AH Gough, RT Dunlay US Patent 6,759,206, 2004 | 72 | 2004 |
| Human biomimetic liver microphysiology systems in drug development and precision medicine A Gough, A Soto-Gutierrez, L Vernetti, MR Ebrahimkhani, AM Stern, ... Nature Reviews Gastroenterology & Hepatology 18 (4), 252-268, 2021 | 69 | 2021 |
| Machine-readable storage medium for analyzing distribution of macromolecules between the cell membrane and the cell cytoplasm RT Dunlay, DL Taylor, AH Gough, KA Giuliano US Patent 7,117,098, 2006 | 68 | 2006 |
| Systems cell biology based on high‐content screening KA Giuliano, PA Johnston, A Gough, DL Taylor Methods in enzymology 414, 601-619, 2006 | 66 | 2006 |
