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Taylor L. Mighell
Taylor L. Mighell
EMBO Postdoctoral Fellow, Centre for Genomic Regulation
Verified email at crg.eu
Title
Cited by
Cited by
Year
A saturation mutagenesis approach to understanding PTEN lipid phosphatase activity and genotype-phenotype relationships
TL Mighell, S Evans-Dutson, BJ O’Roak
The American Journal of Human Genetics 102 (5), 943-955, 2018
1752018
AAV-mediated CRISPR/Cas9 gene editing in murine phenylketonuria
DY Richards, SR Winn, S Dudley, S Nygaard, TL Mighell, M Grompe, ...
Molecular Therapy-Methods & Clinical Development 17, 234-245, 2020
772020
An integrated deep-mutational-scanning approach provides clinical insights on PTEN genotype-phenotype relationships
TL Mighell, S Thacker, E Fombonne, C Eng, BJ O’Roak
The American Journal of Human Genetics 106 (6), 818-829, 2020
382020
A sort-seq approach to the development of single fluorescent protein biosensors
JN Koberstein, ML Stewart, TL Mighell, CB Smith, MS Cohen
ACS chemical biology 16 (9), 1709-1720, 2021
132021
SUNi mutagenesis: Scalable and uniform nicking for efficient generation of variant libraries
TL Mighell, I Toledano, B Lehner
Plos one 18 (7), e0288158, 2023
12023
Crispr-mediated capture of nucleic acids
BJ O'roak, A Andrew, T Mighell, R Mulqueen, C Thornton
US Patent App. 17/753,592, 2022
2022
Cas12a-Capture: a novel, low-cost, and scalable method for targeted sequencing
TL Mighell, A Nishida, BL O'connell, CV Miller, S Grindstaff, CA Thornton, ...
The CRISPR Journal 5 (4), 548-557, 2022
2022
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