Immunobiology and immunotherapy of HCC: spotlight on innate and innate-like immune cells B Ruf, B Heinrich, TF Greten Cellular & molecular immunology 18 (1), 112-127, 2021 | 182 | 2021 |
Gut microbiome directs hepatocytes to recruit MDSCs and promote cholangiocarcinoma Q Zhang, C Ma, Y Duan, B Heinrich, U Rosato, LP Diggs, L Ma, S Roy, ... Cancer discovery 11 (5), 1248-1267, 2021 | 140 | 2021 |
CD40-mediated immune cell activation enhances response to anti-PD-1 in murine intrahepatic cholangiocarcinoma LP Diggs, B Ruf, C Ma, B Heinrich, L Cui, Q Zhang, JC McVey, S Wabitsch, ... Journal of hepatology 74 (5), 1145-1154, 2021 | 86 | 2021 |
The tumour microenvironment shapes innate lymphoid cells in patients with hepatocellular carcinoma B Heinrich, EM Gertz, AA Schäffer, A Craig, B Ruf, V Subramanyam, ... Gut 71 (6), 1161-1175, 2022 | 72 | 2022 |
Metformin treatment rescues CD8+ T-cell response to immune checkpoint inhibitor therapy in mice with NAFLD S Wabitsch, JD McCallen, O Kamenyeva, B Ruf, JC McVey, J Kabat, ... Journal of hepatology 77 (3), 748-760, 2022 | 63 | 2022 |
Steatohepatitis impairs T-cell–directed immunotherapies against liver tumors in mice B Heinrich, ZJ Brown, LP Diggs, M Vormehr, C Ma, V Subramanyam, ... Gastroenterology 160 (1), 331-345. e6, 2021 | 53 | 2021 |
Platelets control liver tumor growth through P2Y12-dependent CD40L release in NAFLD C Ma, Q Fu, LP Diggs, JC McVey, J McCallen, S Wabitsch, B Ruf, Z Brown, ... Cancer cell 40 (9), 986-998. e5, 2022 | 33 | 2022 |
Videoconference clinics improve efficiency of inflammatory bowel disease care in a remote and rural setting B Ruf, P Jenkinson, D Armour, M Fraser, AJM Watson Journal of telemedicine and telecare 26 (9), 545-551, 2020 | 31 | 2020 |
Activating mucosal-associated invariant T cells induces a broad antitumor response B Ruf, VV Catania, S Wabitsch, C Ma, LP Diggs, Q Zhang, B Heinrich, ... Cancer immunology research 9 (9), 1024-1034, 2021 | 30 | 2021 |
Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma B Ruf, S Berchtold, S Venturelli, M Burkard, I Smirnow, T Prenzel, ... Molecular Therapy-Oncolytics 2, 15019, 2015 | 29 | 2015 |
Assessment of current virotherapeutic application schemes:“hit hard and early” versus “killing softly”? B Ruf, UM Lauer Molecular Therapy-Oncolytics 2, 2015 | 21 | 2015 |
Innate lymphoid cells and innate-like T cells in cancer—at the crossroads of innate and adaptive immunity B Ruf, TF Greten, F Korangy Nature Reviews Cancer 23 (6), 351-371, 2023 | 19 | 2023 |
Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin B Ruf, M Bruhns, S Babaei, N Kedei, L Ma, M Revsine, MR Benmebarek, ... Cell 186 (17), 3686-3705. e32, 2023 | 18 | 2023 |
Anti–PD-1 in Combination With Trametinib Suppresses Tumor Growth and Improves Survival of Intrahepatic Cholangiocarcinoma in Mice S Wabitsch, M Tandon, B Ruf, Q Zhang, JD McCallen, JC McVey, C Ma, ... Cellular and Molecular Gastroenterology and Hepatology 12 (3), 1166-1178, 2021 | 17 | 2021 |
Phase I/II study of PexaVec in combination with immune checkpoint inhibition in refractory metastatic colorectal cancer C Monge, C Xie, Y Myojin, K Coffman, DM Hrones, S Wang, ... Journal for Immunotherapy of Cancer 11 (2), 2023 | 14 | 2023 |
NAFLD indirectly impairs antigen-specific CD8+ T cell immunity against liver cancer in mice JC McVey, BL Green, B Ruf, JD McCallen, S Wabitsch, V Subramanyam, ... Iscience 25 (2), 103847, 2022 | 12 | 2022 |
Hydroxychloroquine can impair tumor response to anti-PD1 in subcutaneous mouse models S Wabitsch, JC McVey, C Ma, B Ruf, O Kamenyeva, JD McCallen, ... Iscience 24 (1), 2021 | 11 | 2021 |
Biomarkers for immunotherapy of hepatocellular carcinoma TF Greten, A Villanueva, F Korangy, B Ruf, M Yarchoan, L Ma, E Ruppin, ... Nature Reviews Clinical Oncology 20 (11), 780-798, 2023 | 10 | 2023 |
Checkpoint inhibitors modulate plasticity of innate lymphoid cells in peripheral blood of patients with hepatocellular carcinoma B Heinrich, B Ruf, V Subramanyam, Y Myojin, CW Lai, AJ Craig, J Fu, ... Frontiers in Immunology 13, 849958, 2022 | 6 | 2022 |
Chromoendoscopy in Combination with Random Biopsies for Patients with Pathogenic CDH1 Mutations Undergoing Endoscopic Surveillance B Ruf, C Roggia, C Schroeder, S Mattern, F Fend, T Klag, M Götz Journal of Gastrointestinal Cancer 54 (2), 520-527, 2023 | 3 | 2023 |