Deletion of CD4 and CD8 coreceptors permits generation of αβT cells that recognize antigens independently of the MHC F Van Laethem, SD Sarafova, JH Park, X Tai, L Pobezinsky, TI Guinter, ... Immunity 27 (5), 735-750, 2007 | 226 | 2007 |
'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR JH Park, S Adoro, PJ Lucas, SD Sarafova, AS Alag, LL Doan, B Erman, ... Nature immunology 8 (10), 1049-1059, 2007 | 200 | 2007 |
Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity SD Sarafova, B Erman, Q Yu, F Van Laethem, T Guinter, SO Sharrow, ... Immunity 23 (1), 75-87, 2005 | 83 | 2005 |
Negative regulation of CD4 gene expression by a HES-1–c-Myb complex RD Allen III, HK Kim, SD Sarafova, G Siu Molecular and cellular biology 21 (9), 3071-3082, 2001 | 80 | 2001 |
Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model B Erman, AS Alag, O Dahle, F van Laethem, SD Sarafova, TI Guinter, ... The journal of Immunology 177 (10), 6613-6625, 2006 | 54 | 2006 |
A potential role for Elf-1 in CD4 promoter function S Sarafova, G Siu Journal of Biological Chemistry 274 (23), 16126-16134, 1999 | 41 | 1999 |
Sequence‐Defined Heteromultivalent Precision Glycomacromolecules Bearing Sulfonated/Sulfated Nonglycosidic Moieties Preferentially Bind Galectin‐3 and Delay Wound Healing of a … T Freichel, V Heine, D Laaf, EE Mackintosh, S Sarafova, L Elling, ... Macromolecular bioscience 20 (9), 2000163, 2020 | 30 | 2020 |
Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice SD Sarafova, F Van Laethem, S Adoro, T Guinter, SO Sharrow, ... Immunity 31 (3), 480-490, 2009 | 21 | 2009 |
Precise arrangement of factor-binding sites is required for murine CD4 promoter function S Sarafova, G Siu Nucleic Acids Research 28 (14), 2664-2671, 2000 | 19 | 2000 |
Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic S Adoro, B Erman, SD Sarafova, F Van Laethem, JH Park, L Feigenbaum, ... The Journal of Immunology 181 (10), 6975-6983, 2008 | 10 | 2008 |
Control of CD4 gene expression: connecting signals to outcomes in T cell development SD Sarafova, G Siu Brazilian journal of medical and biological research 32, 785-803, 1999 | 8 | 1999 |
Deletion of the highly conserved functional region of the Cd4 enhancer NCE in RLM11 cells using CRISPR/Cas9 reduces CD4 expression SD Sarafova, C Futral, P Brennan, M Guzynski The Journal of Immunology 200 (1_Supplement), 165.12-165.12, 2018 | 2 | 2018 |
Contribution of the Microbiome to Maintenance of the CD4: CD8 Ratio in Inbred and Congenic Mouse Strains SD Sarafova, K Soden, S Dankwa, A Watt, D Thurtle-Schmidt The Journal of Immunology 204 (1_Supplement), 83.9-83.9, 2020 | | 2020 |
Contribution of the microbiome to maintenance of the CD4: CD8 ratio in inbred and congenic mouse strains G Campbell, S Dankwa, C Hammett, N Schork, K Soden, A Watt, ... EUROPEAN JOURNAL OF IMMUNOLOGY 49, 1319-1320, 2019 | | 2019 |
A chemical genetic approach to interrogate the staphylococcal heme sensing system MC Surdel Vanderbilt University, 2016 | | 2016 |
Identification of a novel, developmental-stage-specific enhancer in the Cd4 gene (P4442) G Swan, S Sarafova The Journal of Immunology 190 (1_Supplement), 52.39-52.39, 2013 | | 2013 |
Targeting CD4 Coreceptor Expression to Postselection Thymocytes Reveals That CD4 S ADORO, B ERMAN, SD SARAFOVA, F VAN LAETHEM, JH PARK, ... The Journal of immunology 181 (10), 6974-6983, 2008 | | 2008 |
118 Coreceptor Tuning: IL-7 Signals Transcriptionally Tailor CD8 Coreceptor Expression in CD8 T Cells to the Self-specificity of their TCR JH Park, S Adoro, PJ Lucas, SD Sarafova, A Alag, LL Doan, B Erman, ... Cytokine 1 (39), 32, 2007 | | 2007 |
Molecular Analysis of CD4 Promoter Function During T Cell Development SD Sarafova Columbia University, 2000 | | 2000 |