Biocatalysis using immobilized enzymes in continuous flow for the synthesis of fine chemicals MP Thompson, I Peñafiel, SC Cosgrove, NJ Turner Organic process research & development 23 (1), 9-18, 2018 | 243 | 2018 |
Highly productive oxidative biocatalysis in continuous flow by enhancing the aqueous equilibrium solubility of oxygen MR Chapman, SC Cosgrove, NJ Turner, N Kapur, AJ Blacker Angewandte Chemie International Edition 57 (33), 10535-10539, 2018 | 69 | 2018 |
Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases J Mangas-Sanchez, M Sharma, SC Cosgrove, JI Ramsden, JR Marshall, ... Chemical science 11 (19), 5052-5057, 2020 | 60 | 2020 |
Enantioselective synthesis of chiral vicinal amino alcohols using amine dehydrogenases FF Chen, SC Cosgrove, WR Birmingham, J Mangas-Sanchez, J Citoler, ... ACS Catalysis 9 (12), 11813-11818, 2019 | 60 | 2019 |
One‐Pot Synthesis of Chiral N‐Arylamines by Combining Biocatalytic Aminations with Buchwald–Hartwig N‐Arylation SC Cosgrove, MP Thompson, ST Ahmed, F Parmeggiani, NJ Turner Angewandte Chemie International Edition 59 (41), 18156-18160, 2020 | 59 | 2020 |
Development of continuous flow systems to access secondary amines through previously incompatible biocatalytic cascades AP Mattey, GJ Ford, J Citoler, C Baldwin, JR Marshall, RB Palmer, ... Angewandte Chemie International Edition 60 (34), 18660-18665, 2021 | 49 | 2021 |
Synergistic chemo/biocatalytic synthesis of alkaloidal tetrahydroquinolines SC Cosgrove, S Hussain, NJ Turner, SP Marsden ACS Catalysis 8 (6), 5570-5573, 2018 | 43 | 2018 |
Imine reductases, reductive aminases, and amine oxidases for the synthesis of chiral amines: discovery, characterization, and synthetic applications SC Cosgrove, A Brzezniak, SP France, JI Ramsden, J Mangas-Sanchez, ... Methods in enzymology 608, 131-149, 2018 | 42 | 2018 |
Radical-mediated direct C–H amination of arenes with secondary amines SC Cosgrove, JMC Plane, SP Marsden Chemical Science 9 (32), 6647-6652, 2018 | 41 | 2018 |
Biocatalytic oxidation in continuous flow for the generation of carbohydrate dialdehydes SC Cosgrove, AP Mattey, M Riese, MR Chapman, WR Birmingham, ... Acs Catalysis 9 (12), 11658-11662, 2019 | 37 | 2019 |
Oxidase enzymes as sustainable oxidation catalysts AJC Wahart, J Staniland, GJ Miller, SC Cosgrove Royal Society Open Science 9 (1), 211572, 2022 | 31 | 2022 |
Is it time for biocatalysis in fragment-based drug discovery? JI Ramsden, SC Cosgrove, NJ Turner Chemical Science 11 (41), 11104-11112, 2020 | 24 | 2020 |
Reaching new biocatalytic reactivity using continuous flow reactors SC Cosgrove, AP Mattey Chemistry–A European Journal 28 (13), e202103607, 2022 | 21 | 2022 |
Enzyme immobilisation on wood-derived cellulose scaffolds via carbohydrate-binding module fusion constructs AD Roberts, KAP Payne, S Cosgrove, V Tilakaratna, I Penafiel, ... Green Chemistry 23 (13), 4716-4732, 2021 | 19 | 2021 |
Advances in biocatalytic and chemoenzymatic synthesis of nucleoside analogues SC Cosgrove, GJ Miller Expert Opinion on Drug Discovery 17 (4), 355-364, 2022 | 18 | 2022 |
Natural heterogeneous catalysis with immobilised oxidase biocatalysts AP Mattey, JJ Sangster, JI Ramsden, C Baldwin, WR Birmingham, ... RSC advances 10 (33), 19501-19505, 2020 | 18 | 2020 |
Rapid model-based optimization of a two-enzyme system for continuous reductive amination in flow W Finnigan, J Citoler, SC Cosgrove, NJ Turner Organic Process Research & Development 24 (10), 1969-1977, 2020 | 17 | 2020 |
Continuous Flow for the Photochemical C‐H Amination of Arenes SPM Sebastian C. Cosgrove, Gayle E. Douglas, Steven A. Raw ChemPhotoChem 2 (10), 851-854, 2018 | 13 | 2018 |
RetroBioCat Database: A Platform for Collaborative Curation and Automated Meta-Analysis of Biocatalysis Data W Finnigan, M Lubberink, LJ Hepworth, J Citoler, AP Mattey, GJ Ford, ... ACS catalysis 13 (17), 11771-11780, 2023 | 7 | 2023 |
Realizing the continuous Chemoenzymatic synthesis of Anilines using an immobilized nitroreductase SC Cosgrove, GJ Miller, A Bornadel, B Dominguez ACS Sustainable Chemistry & Engineering 11 (23), 8556-8561, 2023 | 7 | 2023 |