SIRT6 promotes DNA repair under stress by activating PARP1 Z Mao, C Hine, X Tian, M Van Meter, M Au, A Vaidya, A Seluanov, ... Science 332 (6036), 1443-1446, 2011 | 905 | 2011 |
SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age M Van Meter, M Kashyap, S Rezazadeh, AJ Geneva, TD Morello, ... Nature communications 5 (1), 5011, 2014 | 399 | 2014 |
LINE1 derepression in aged wild-type and SIRT6-deficient mice drives inflammation M Simon, M Van Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, ... Cell metabolism 29 (4), 871-885. e5, 2019 | 346 | 2019 |
Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence Z Mao, X Tian, M Van Meter, Z Ke, V Gorbunova, A Seluanov Proceedings of the National Academy of Sciences 109 (29), 11800-11805, 2012 | 189 | 2012 |
SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells M Van Meter, Z Mao, V Gorbunova, A Seluanov Cell cycle 10 (18), 3153-3158, 2011 | 180 | 2011 |
JNK phosphorylates SIRT6 to stimulate DNA double-strand break repair in response to oxidative stress by recruiting PARP1 to DNA breaks M Van Meter, M Simon, G Tombline, A May, TD Morello, BP Hubbard, ... Cell reports 16 (10), 2641-2650, 2016 | 134 | 2016 |
SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner Z Xu, L Zhang, W Zhang, DU Meng, H Zhang, Y Jiang, X Xu, M Van Meter, ... Cell cycle 14 (2), 269-276, 2015 | 112 | 2015 |
Common and rare variant associations with clonal haematopoiesis phenotypes MD Kessler, A Damask, S O’Keeffe, N Banerjee, D Li, K Watanabe, ... Nature 612 (7939), 301-309, 2022 | 91 | 2022 |
Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair M Van Meter, Z Mao, V Gorbunova, A Seluanov Aging (Albany NY) 3 (9), 829, 2011 | 85 | 2011 |
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ... The EMBO Journal 41 (21), e110393, 2022 | 22 | 2022 |
IGF1R levels in the brain negatively correlate with longevity in 16 rodent species J Azpurua, JN Yang, M Van Meter, Z Liu, J Kim, AABL Ladd, AA Coppi, ... Aging (Albany NY) 5 (4), 304, 2013 | 20 | 2013 |
Exome sequencing of 628,388 individuals identifies common and rare variant associations with clonal hematopoiesis phenotypes MD Kessler, A Damask, S O’Keeffe, M Van Meter, N Banerjee, S Semrau, ... MedRxiv, 2021.12. 29.21268342, 2022 | 15 | 2022 |
SIRT6: a promising target for cancer prevention and therapy M Van Meter, V Gorbunova, A Seluanov Anticancer Genes, 181-196, 2014 | 15 | 2014 |
Effects of an unusual poison identify a lifespan role for Topoisomerase 2 in Saccharomyces cerevisiae G Tombline, JI Millen, B Polevoda, M Rapaport, B Baxter, M Van Meter, ... Aging (Albany NY) 9 (1), 68, 2017 | 13 | 2017 |
Therapeutic targeting of Notch signaling and immune checkpoint blockade in a spontaneous, genetically heterogeneous mouse model of T-cell acute lymphoblastic leukemia J Gao, M Van Meter, S Hernandez Lopez, G Chen, Y Huang, S Ren, ... Disease models & mechanisms 12 (9), dmm040931, 2019 | 11 | 2019 |
Forever young? Exploring the link between rapamycin, longevity and cancer M Van Meter, A Seluanov, V Gorbunova Cell Cycle 11 (23), 4296-4297, 2012 | 6 | 2012 |
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ... The EMBO Journal 42 (3), e113326, 2023 | 3 | 2023 |
Comparative Biology of Aging: Insights from Long-Lived Rodent Species M Van Meter, V Gorbunova, A Seluanov Handbook of the Biology of Aging 8, 305–324, 2015 | 3 | 2015 |
Inhibition of retrotransposition improves health and extends lifespan of SIRT6 knockout mice M Simon, MV Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, MD Cecco, ... bioRxiv, 460808, 2018 | 2 | 2018 |
Anti-ptcra antibody-drug conjugates and uses thereof F Kuhnert, M Van Meter, T Nittoli US Patent App. 18/482,448, 2024 | | 2024 |