| Roles for synonymous codon usage in protein biogenesis JL Chaney, PL Clark Annual review of biophysics 44, 143-166, 2015 | 285 | 2015 |
| Pertactin β-helix folding mechanism suggests common themes for the secretion and folding of autotransporter proteins M Junker, CC Schuster, AV McDonnell, KA Sorg, MC Finn, B Berger, ... Proceedings of the National Academy of Sciences 103 (13), 4918-4923, 2006 | 236 | 2006 |
| Protein folding in the cell: reshaping the folding funnel PL Clark Trends in biochemical sciences 29 (10), 527-534, 2004 | 225 | 2004 |
| Rare codons cluster TFC Iv, PL Clark Plos One 3 (10), 1-5, 2008 | 222* | 2008 |
| Rare codons cluster TF Clarke IV, PL Clark PloS one 3 (10), 2008 | 222 | 2008 |
| Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water JA Riback, MA Bowman, AM Zmyslowski, CR Knoverek, JM Jumper, ... Science 358 (6360), 238-241, 2017 | 203 | 2017 |
| Vectorial transport and folding of an autotransporter virulence protein during outer membrane secretion M Junker, RN Besingi, PL Clark Molecular microbiology 71 (5), 1323-1332, 2009 | 159 | 2009 |
| Synonymous codon substitutions perturb cotranslational protein folding in vivo and impair cell fitness IM Walsh, MA Bowman, IFS Santarriaga, A Rodriguez, PL Clark Proceedings of the National Academy of Sciences 117 (7), 3528-3534, 2020 | 158 | 2020 |
| Expanding Anfinsen’s principle: contributions of synonymous codon selection to rational protein design IM Sander, JL Chaney, PL Clark Journal of the American Chemical Society 136 (3), 858-861, 2014 | 154 | 2014 |
| Cotranslational folding promotes β-helix formation and avoids aggregation in vivo MS Evans, IM Sander, PL Clark Journal of molecular biology 383 (3), 683-692, 2008 | 135 | 2008 |
| Folding the proteome E Braselmann, JL Chaney, PL Clark Trends in biochemical sciences 38 (7), 337-344, 2013 | 122 | 2013 |
| Widespread position-specific conservation of synonymous rare codons within coding sequences JL Chaney, A Steele, R Carmichael, A Rodriguez, AT Specht, K Ngo, J Li, ... PLoS computational biology 13 (5), e1005531, 2017 | 115 | 2017 |
| Intrinsic tryptophans of CRABPI as probes of structure and folding PL Clark, ZP Liu, J Zhang, LM Gierasch Protein science 5 (6), 1108-1117, 1996 | 115 | 1996 |
| Distinct cysteine sulfhydryl environments detected by analysis of Raman SH markers of Cys→ Ser mutant proteins SW Raso, PL Clark, C Haase-Pettingell, J King, GJ Thomas Jr Journal of Molecular Biology 307 (3), 899-911, 2001 | 110 | 2001 |
| A newly synthesized, ribosome-bound polypeptide chain adopts conformations dissimilar from early in vitrorefolding intermediates PL Clark, J King Journal of Biological Chemistry 276 (27), 25411-25420, 2001 | 100 | 2001 |
| Homogeneous stalled ribosome nascent chain complexes produced in vivo or in vitro MS Evans, KG Ugrinov, MA Frese, PL Clark Nature methods 2 (10), 757-762, 2005 | 97 | 2005 |
| Quality over quantity: optimizing co-translational protein folding with non-‘optimal’synonymous codons GN Jacobson, PL Clark Current opinion in structural biology 38, 102-110, 2016 | 82 | 2016 |
| Cotranslational folding increases GFP folding yield KG Ugrinov, PL Clark Biophysical Journal 98 (7), 1312-1320, 2010 | 81 | 2010 |
| Probing the folding pathway of a β-clam protein with single-tryptophan constructs PL Clark, BF Weston, LM Gierasch Folding and Design 3 (5), 401-412, 1998 | 75 | 1998 |
| Cavity formation before stable hydrogen bonding in the folding of a beta-clam protein. PL Clark, ZP Liu, J Rizo, LM Gierasch Nature structural biology 4 (11), 883-886, 1997 | 71 | 1997 |
