Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles LC Shuhaibar, JR Egbert, RP Norris, PD Lampe, VO Nikolaev, ... Proceedings of the National Academy of Sciences 112 (17), 5527-5532, 2015 | 165 | 2015 |
Luteinizing hormone reduces the activity of the NPR2 guanylyl cyclase in mouse ovarian follicles, contributing to the cyclic GMP decrease that promotes resumption of meiosis in … JW Robinson, M Zhang, LC Shuhaibar, RP Norris, A Geerts, F Wunder, ... Developmental biology 366 (2), 308-316, 2012 | 165 | 2012 |
Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes JR Egbert, LC Shuhaibar, AB Edmund, DA Van Helden, JW Robinson, ... Development 141 (18), 3594-3604, 2014 | 113 | 2014 |
Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone LC Shuhaibar, JR Egbert, AB Edmund, TF Uliasz, DM Dickey, SP Yee, ... Developmental biology 409 (1), 194-201, 2016 | 58 | 2016 |
Luteinizing hormone causes phosphorylation and activation of the cGMP phosphodiesterase PDE5 in rat ovarian follicles, contributing, together with PDE1 activity, to the … JR Egbert, TF Uliasz, LC Shuhaibar, A Geerts, F Wunder, RJ Kleiman, ... Biology of reproduction 94 (5), 110, 1-11, 2016 | 53 | 2016 |
Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor JLA Shuhaibar LC1, Robinson JW2, Vigone G1, Shuhaibar NP1, Egbert JR1, Baena ... eLife, 2017 | 31 | 2017 |
Multiple cAMP phosphodiesterases act together to prevent premature oocyte meiosis and ovulation G Vigone, LC Shuhaibar, JR Egbert, TF Uliasz, MA Movsesian, LA Jaffe Endocrinology 159 (5), 2142-2152, 2018 | 19 | 2018 |
Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth LC Shuhaibar, N Kaci, JR Egbert, T Horville, L Loisay, G Vigone, ... JCI insight 6 (9), 2021 | 10 | 2021 |
The phosphatase inhibitor LB-100 acts synergistically with the NPR2 agonist BMN-111 to improve bone growth LC Shuhaibar, N Kaci, JR Egbert, L Loisay, G Vigone, TF Uliasz, ... bioRxiv, 2020.09. 10.288589, 2020 | 1 | 2020 |
Preparing for Fertilization: Intercellular Signals for Oocyte Maturation LC Shuhaibar, DJ Carroll, LA Jaffe Reproductive and Developmental Strategies: The Continuity of Life, 535-548, 2018 | 1 | 2018 |
Luteinizing Hormone Reduces Guanylyl Cyclase Activity in the Granulosa Cells of the Mouse Ovary, Leading to the Resumption of Meiosis in the Oocyte JW Robinson, LC Shuhaibar, JJ Eppig, LR Potter, LA Jaffe Molecular Biology of the Cell 22, 2011 | 1 | 2011 |
A new combination therapy for the treatment of fgfr3-related skeletal disease L Legeai-Mallet, L Jaffe, L Shuhaibar US Patent App. 18/003,783, 2023 | | 2023 |
FGF-inhibition of NPR2-mediated Cyclic cGMP Production in Growth Plate Chondrocytes Is Reversed by the Phosphatase Inhibitor LB-100 LC Shuhaibar, G Vigone, LA Jaffe JOURNAL OF BONE AND MINERAL RESEARCH 33, 196-197, 2018 | | 2018 |
Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications: Bamberg, Germany. 23-25 June, 2017 G Todd Milne, Ironwood team, P Sandner, KA Lincoln, PC Harrison, ... BMC Pharmacology and Toxicology 18, 1-35, 2017 | | 2017 |
Luteinizing Hormone Causes Phosphorylation and Activation of the cyclic GMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the … JR Egbert, TF Uliasz, LC Shuhaibar, A Geerts, F Wunder, RJ Kleiman, ... | | 2016 |
Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase regulates oocyte meiotic resumption LC Shuhaibar, AB Edmund, JR Egbert, SP Yee, LR Potter, LA Jaffe BMC Pharmacology and Toxicology 16, 1-2, 2015 | | 2015 |
Hormonal Control of Meiosis by Cyclic GMP and the Guanylyl Cyclase NPR2 in the Mouse Ovarian Follicle LC Shuhaibar | | 2015 |
cGMP indicator mice: Generation, characterization and first in vivo results M Thunemann, W Lai, S Feil, B Birk, M Russwurm, L Shuhaibar, L Jaffe, ... NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 387, S20-S20, 2014 | | 2014 |
Cyclic GMP-mediated intercellular communication in mammalian ovarian follicles LA Jaffe, JR Egbert, LC Shuhaibar, L Wen, M Thunemann, R Feil, ... BMC Pharmacology and Toxicology 14, 1-2, 2013 | | 2013 |
Regulation of MAPK and MEK During Maturation and Fertilization of the Sea Star LC Shuhaibar Florida Institute of Technology, 2009 | | 2009 |