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Mahesh K C
Mahesh K C
Nationwide Children's Hospital
Verified email at NATIONWIDECHILDRENS.ORG
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Year
Farm stage, bird age, and body site dominantly affect the quantity, taxonomic composition, and dynamics of respiratory and gut microbiota of commercial layer chickens
JM Ngunjiri, KJM Taylor, MC Abundo, H Jang, M Elaish, M Kc, A Ghorbani, ...
Applied and environmental microbiology 85 (9), e03137-18, 2019
722019
A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike
M Lu, P Dravid, Y Zhang, S Trivedi, A Li, O Harder, M Kc, ...
Proceedings of the National Academy of Sciences 118 (12), e2026153118, 2021
552021
Efficacy and synergy of live-attenuated and inactivated influenza vaccines in young chickens
H Jang, M Elaish, M Kc, MC Abundo, A Ghorbani, JM Ngunjiri, CW Lee
PLoS One 13 (4), e0195285, 2018
412018
Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis
MM Eltobgy, A Zani, AD Kenney, S Estfanous, E Kim, A Badr, C Carafice, ...
Proceedings of the National Academy of Sciences 119 (21), e2202012119, 2022
32*2022
SARS-CoV-2 prefusion spike protein stabilized by six rather than two prolines is more potent for inducing antibodies that neutralize viral variants of concern
M Lu, M Chamblee, Y Zhang, C Ye, P Dravid, JG Park, KC Mahesh, ...
Proceedings of the National Academy of Sciences 119 (35), e2110105119, 2022
282022
Respiratory and gut microbiota in commercial turkey flocks with disparate weight gain trajectories display differential compositional dynamics
KJM Taylor, JM Ngunjiri, MC Abundo, H Jang, M Elaish, A Ghorbani, M Kc, ...
Applied and environmental microbiology 86 (12), e00431-20, 2020
192020
Heterosubtypic protection against avian influenza virus by live attenuated and chimeric norovirus P-particle-M2e vaccines in chickens
A Ghorbani, JM Ngunjiri, M Xia, M Elaish, H Jang, KC Mahesh, ...
Vaccine 37 (10), 1356-1364, 2019
182019
Interferon‐induced transmembrane protein 3 (IFITM3) limits lethality of SARS‐CoV‐2 in mice
AD Kenney, A Zani, J Kawahara, AC Eddy, XL Wang, KC Mahesh, M Lu, ...
EMBO reports 24 (4), e56660, 2023
17*2023
A highly efficacious live attenuated mumps virus–based SARS-CoV-2 vaccine candidate expressing a six-proline stabilized prefusion spike
Y Zhang, M Lu, KC Mahesh, E Kim, MM Shamseldin, C Ye, P Dravid, ...
Proceedings of the National Academy of Sciences 119 (33), e2201616119, 2022
132022
Assessment of two DNA extraction kits for profiling poultry respiratory microbiota from multiple sample types
MEC Abundo, JM Ngunjiri, KJM Taylor, H Ji, A Ghorbani, M KC, BP Weber, ...
PLoS One 16 (1), e0241732, 2021
102021
A methyltransferase-defective vesicular stomatitis virus-based SARS-CoV-2 vaccine candidate provides complete protection against SARS-CoV-2 infection in hamsters
M Lu, Y Zhang, P Dravid, A Li, C Zeng, M Kc, S Trivedi, H Sharma, ...
Journal of virology 95 (20), 10.1128/jvi. 00592-21, 2021
92021
Protective immunity against influenza virus challenge by norovirus P particle-M2e and HA2-AtCYN vaccines in chickens
M Elaish, M Xia, JM Ngunjiri, A Ghorbani, H Jang, KC Mahesh, ...
Vaccine 37 (43), 6454-6462, 2019
82019
Specific-pathogen-free Turkey model for reoviral arthritis
JM Ngunjiri, A Ghorbani, H Jang, S Waliullah, M Elaish, MC Abundo, ...
Veterinary microbiology 235, 170-179, 2019
72019
Prime-pull immunization of mice with a BcfA-adjuvanted vaccine elicits sustained mucosal immunity that prevents SARS-CoV-2 infection and pathology
MM Shamseldin, A Kenney, A Zani, JP Evans, C Zeng, KA Read, JM Hall, ...
The Journal of Immunology 210 (9), 1257-1271, 2023
52023
TLR3 and MDA5 knockout DF-1 cells enhance replication of avian orthoavulavirus 1
CW Lee, M Kc, JM Ngunjiri, A Ghorbani, K Lee
Avian Diseases 67 (1), 94-101, 2023
52023
Evaluation of sampling methods for the study of avian respiratory microbiota
MEC Abundo, JM Ngunjiri, KJM Taylor, H Ji, A Ghorbani, M Kc, M Elaish, ...
Avian Diseases 64 (3), 277-285, 2020
52020
Sero-prevalence of porcine reproductive and respiratory syndrome (PRRS) in pigs of different developmental regions of Nepal
KC Mahesh, BR Joshi, SP Shrestha, M Prajapati, D Kathayat, S Dhakal
International Journal of Applied Sciences and Biotechnology 3 (2), 218-222, 2015
52015
Avian Toll-like receptor 3 isoforms and evaluation of Toll-like receptor 3–mediated immune responses using knockout quail fibroblast cells
KC Mahesh, JM Ngunjiri, J Lee, J Ahn, M Elaish, A Ghorbani, ...
Poultry science 99 (12), 6513-6524, 2020
42020
Coronaviruses in animals and humans, COVID-19 pandemic and one health approach
KC Mahesh, S Ghimire, N Bhattarai, S Dhakal
Applied Science and Technology Annals 1 (1), 187-193, 2020
32020
Recombinant measles virus expressing prefusion spike protein stabilized by six rather than two prolines is more efficacious against SARS‐CoV‐2 infection
Y Zhang, M Lu, I Thongpan, J Xu, M Kc, P Dravid, S Trivedi, H Sharma, ...
Journal of Medical Virology 95 (4), e28687, 2023
22023
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