| Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura X Zheng, D Chung, TK Takayama, EM Majerus, JE Sadler, K Fujikawa Journal of Biological Chemistry 276 (44), 41059-41063, 2001 | 1087 | 2001 |
| Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic … XL Zheng, RM Kaufman, LT Goodnough, JE Sadler Blood 103 (11), 4043-4049, 2004 | 540 | 2004 |
| Pathogenesis of thrombotic microangiopathies XL Zheng, JE Sadler Annu. Rev. Pathol. Mech. Dis. 3, 249-277, 2008 | 283 | 2008 |
| ISTH guidelines for treatment of thrombotic thrombocytopenic purpura XL Zheng, SK Vesely, SR Cataland, P Coppo, B Geldziler, A Iorio, ... Journal of Thrombosis and Haemostasis 18 (10), 2496-2502, 2020 | 269 | 2020 |
| ADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpura XL Zheng Annual review of medicine 66, 211-225, 2015 | 257 | 2015 |
| Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13 X Zheng, K Nishio, EM Majerus, JE Sadler Journal of Biological Chemistry 278 (32), 30136-30141, 2003 | 244 | 2003 |
| ISTH guidelines for the diagnosis of thrombotic thrombocytopenic purpura XL Zheng, SK Vesely, SR Cataland, P Coppo, B Geldziler, A Iorio, ... Journal of Thrombosis and Haemostasis 18 (10), 2486-2495, 2020 | 206 | 2020 |
| Incomplete embryonic lethality and fatal neonatal hemorrhage caused by prothrombin deficiency in mice J Xue, Q Wu, LA Westfield, EA Tuley, D Lu, Q Zhang, K Shim, X Zheng, ... Proceedings of the National Academy of Sciences 95 (13), 7603-7607, 1998 | 191 | 1998 |
| Binding of platelet glycoprotein Ibα to von Willebrand factor domain A1 stimulates the cleavage of the adjacent domain A2 by ADAMTS13 K Nishio, PJ Anderson, XL Zheng, JE Sadler Proceedings of the National Academy of Sciences 101 (29), 10578-10583, 2004 | 190 | 2004 |
| Blood coagulation factor X deficiency causes partial embryonic lethality and fatal neonatal bleeding in mice M Dewerchin, Z Liang, L Moons, P Carmeliet, FJ Castellino, D Collen, ... Thrombosis and haemostasis 83 (02), 185-190, 2000 | 183 | 2000 |
| Remission of chronic thrombotic thrombocytopenic purpura after treatment with cyclophosphamide and rituximab X Zheng, AM Pallera, LT Goodnough, JE Sadler, MA Blinder Annals of internal medicine 138 (2), 105-108, 2003 | 163 | 2003 |
| Structure–function and regulation of ADAMTS‐13 protease XL Zheng Journal of Thrombosis and Haemostasis 11, 11-23, 2013 | 162 | 2013 |
| Cleavage of the ADAMTS13 propeptide is not required for protease activity EM Majerus, X Zheng, EA Tuley, JE Sadler Journal of Biological Chemistry 278 (47), 46643-46648, 2003 | 161 | 2003 |
| Thrombotic thrombocytopenic purpura: pathogenesis, diagnosis and potential novel therapeutics M Saha, JK McDaniel, XL Zheng Journal of Thrombosis and Haemostasis 15 (10), 1889-1900, 2017 | 159 | 2017 |
| Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura XL Zheng, HM Wu, D Shang, E Falls, CG Skipwith, SR Cataland, ... Haematologica 95 (9), 1555, 2010 | 151 | 2010 |
| The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow P Zhang, W Pan, AH Rux, BS Sachais, XL Zheng Blood, The Journal of the American Society of Hematology 110 (6), 1887-1894, 2007 | 148 | 2007 |
| Inflammatory cytokines inhibit ADAMTS13 synthesis in hepatic stellate cells and endothelial cells WJ Cao, M Niiya, XW Zheng, DZ Shang, XL Zheng Journal of Thrombosis and Haemostasis 6 (7), 1233-1235, 2008 | 145 | 2008 |
| Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura C Jian, J Xiao, L Gong, CG Skipwith, SY Jin, HC Kwaan, XL Zheng Blood, The Journal of the American Society of Hematology 119 (16), 3836-3843, 2012 | 143 | 2012 |
| The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor J Ai, P Smith, S Wang, P Zhang, XL Zheng Journal of Biological Chemistry 280 (33), 29428-29434, 2005 | 142 | 2005 |
| Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site TJ Raife, W Cao, BS Atkinson, B Bedell, RR Montgomery, SR Lentz, ... Blood, The Journal of the American Society of Hematology 114 (8), 1666-1674, 2009 | 138 | 2009 |
Wenjing CaoUniversity of Kansas Medical CenterVerified email at kumc.edu
