Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration BR Hoover, MN Reed, J Su, RD Penrod, LA Kotilinek, MK Grant, R Pitstick, ... Neuron 68 (6), 1067-1081, 2010 | 1131 | 2010 |
Brain amyloid-β oligomers in ageing and Alzheimer’s disease SE Lesne, MA Sherman, M Grant, M Kuskowski, JA Schneider, ... Brain 136 (5), 1383-1398, 2013 | 511 | 2013 |
Quaternary structure defines a large class of amyloid-β oligomers neutralized by sequestration P Liu, MN Reed, LA Kotilinek, MKO Grant, CL Forster, W Qiang, ... Cell reports 11 (11), 1760-1771, 2015 | 166 | 2015 |
Correlation of specific amyloid-β oligomers with tau in cerebrospinal fluid from cognitively normal older adults M Handoko, M Grant, M Kuskowski, KR Zahs, A Wallin, K Blennow, ... JAMA neurology 70 (5), 594-599, 2013 | 79 | 2013 |
Synthesis and pharmacological evaluation of dimeric muscarinic acetylcholine receptor agonists A Christopoulos, MKO Grant, N Ayoubzadeh, ON Kim, P Sauerberg, ... Journal of Pharmacology and Experimental Therapeutics 298 (3), 1260-1268, 2001 | 70 | 2001 |
Synthesis and evaluation of xanomeline analogs—probing the wash-resistant phenomenon at the M1 muscarinic acetylcholine receptor BE Kane, MKO Grant, EE El-Fakahany, DM Ferguson Bioorganic & medicinal chemistry 16 (3), 1376-1392, 2008 | 55 | 2008 |
Co-administration of resveratrol with doxorubicin in young mice attenuates detrimental late-occurring cardiovascular changes N Matsumura, BN Zordoky, IM Robertson, SM Hamza, N Parajuli, ... Cardiovascular research 114 (10), 1350-1359, 2018 | 53 | 2018 |
Longitudinal testing of hippocampal plasticity reveals the onset and maintenance of endogenous human Aß-induced synaptic dysfunction in individual freely behaving pre-plaque … Y Qi, I Klyubin, SC Harney, NW Hu, WK Cullen, MK Grant, J Steffen, ... Acta neuropathologica communications 2, 1-15, 2014 | 46 | 2014 |
Persistent binding and functional antagonism by xanomeline at the muscarinic M5 receptor MKO Grant, EE El-Fakahany Journal of Pharmacology and Experimental Therapeutics 315 (1), 313-319, 2005 | 43 | 2005 |
Leveraging the cardio-protective and anticancer properties of resveratrol in cardio-oncology IY Abdelgawad, MKO Grant, BN Zordoky Nutrients 11 (3), 627, 2019 | 33 | 2019 |
Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice MKO Grant, DM Seelig, LC Sharkey, WSV Choi, IY Abdelgawad, ... PLoS One 14 (2), e0212486, 2019 | 29 | 2019 |
Sex-dependent alteration of cardiac cytochrome P450 gene expression by doxorubicin in C57Bl/6 mice MKO Grant, DM Seelig, LC Sharkey, BN Zordoky Biology of sex differences 8, 1-13, 2017 | 26 | 2017 |
CYP1B1 as a therapeutic target in cardio-oncology AN Carrera, MKO Grant, BN Zordoky Clinical Science 134 (21), 2897-2927, 2020 | 24 | 2020 |
Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction MKO Grant, IY Abdelgawad, CA Lewis, D Seelig, BN Zordoky PLoS One 15 (7), e0232507, 2020 | 24 | 2020 |
Anticancer effects of resveratrol in canine hemangiosarcoma cell lines A Carlson, KS Alderete, MKO Grant, DM Seelig, LC Sharkey, ... Veterinary and comparative oncology 16 (2), 253-261, 2018 | 24 | 2018 |
Endogenous expression of nNOS protein in several neuronal cell lines MKO Grant, AE Cuadra, EE El-Fakahany Life sciences 71 (7), 813-817, 2002 | 21 | 2002 |
Human cerebrospinal fluid 6E10-immunoreactive protein species contain amyloid precursor protein fragments MKO Grant, M Handoko, M Rozga, G Brinkmalm, E Portelius, K Blennow, ... PLoS One 14 (2), e0212815, 2019 | 16 | 2019 |
Therapeutic interventions targeting the nitric oxide system: Current and potential uses in obstetrics, bone disease and erectile dysfunction MKO Grant, EE El-Fakahany Life sciences 74 (14), 1701-1721, 2004 | 16 | 2004 |
Sexual dimorphism in doxorubicin-induced systemic inflammation: implications for hepatic cytochrome P450 regulation MKO Grant, IY Abdelgawad, CA Lewis, BN Zordoky International journal of molecular sciences 21 (4), 1279, 2020 | 15 | 2020 |
Transducer abstraction: a novel approach to the detection of partial agonist efficacy in radioligand binding studies A Christopoulos, MKO Grant, EE El-Fakahany Journal of pharmacological and toxicological methods 43 (1), 55-67, 2000 | 12 | 2000 |