Increase in long-chain polyunsaturated fatty acid n− 6/n− 3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease J Araya, R Rodrigo, LA Videla, L Thielemann, M Orellana, P Pettinelli, ... Clinical science 106 (6), 635-643, 2004 | 820 | 2004 |
Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients LA Videla, R Rodrigo, M Orellana, V Fernandez, G Tapia, L Quiñones, ... Clinical science 106 (3), 261-268, 2004 | 600 | 2004 |
Up-regulation of PPAR-γ mRNA expression in the liver of obese patients: an additional reinforcing lipogenic mechanism to SREBP-1c induction P Pettinelli, LA Videla The Journal of Clinical Endocrinology & Metabolism 96 (5), 1424-1430, 2011 | 372 | 2011 |
Experimental alcohol-induced hepatic necrosis: suppression by propylthiouracil. Y Israel, H Kalant, H Orrego, JM Khanna, L Videla, JM Phillips Proceedings of the National Academy of Sciences 72 (3), 1137-1141, 1975 | 322 | 1975 |
Oxidative stress and depletion of hepatic long-chain polyunsaturated fatty acids may contribute to nonalcoholic fatty liver disease LA Videla, R Rodrigo, J Araya, J Poniachik Free Radical Biology and Medicine 37 (9), 1499-1507, 2004 | 316 | 2004 |
Alcohol ingestion, liver glutathione and lipoperoxidation: metabolic interrelations and pathological implications LA Videla, A Valenzuela Life Sciences 31 (22), 2395-2407, 1982 | 315 | 1982 |
Enhancement in liver SREBP-1c/PPAR-α ratio and steatosis in obese patients: correlations with insulin resistance and n-3 long-chain polyunsaturated fatty acid depletion P Pettinelli, T Del Pozo, J Araya, R Rodrigo, AV Araya, G Smok, ... Biochimica Et Biophysica Acta (BBA)-molecular basis of disease 1792 (11 …, 2009 | 260 | 2009 |
N-3 PUFA supplementation triggers PPAR-α activation and PPAR-α/NF-κB interaction: anti-inflammatory implications in liver ischemia-reperfusion injury J Zúñiga, M Cancino, F Medina, P Varela, R Vargas, G Tapia, LA Videla, ... PloS one 6 (12), e28502, 2011 | 239 | 2011 |
Metabolic alterations produced in the liver by chronic ethanol administration. Increased oxidative capacity L Videla, J Bernstein, Y Israel Biochemical Journal 134 (2), 507-514, 1973 | 239 | 1973 |
Factors that modify the metabolism of ethanol in rat liver and adaptive changes produced by its chronic administration L Videla, Y Israel Biochemical Journal 118 (2), 275-281, 1970 | 227 | 1970 |
Insulin resistance and oxidative stress interdependency in non-alcoholic fatty liver disease LA Videla, R Rodrigo, J Araya, J Poniachik Trends in molecular medicine 12 (12), 555-558, 2006 | 215 | 2006 |
Silymarin protection against hepatic lipid peroxidation induced by acute ethanol intoxication in the rat A Valenzuela, C Lagos, K Schmidt, LA Videla Biochemical pharmacology 34 (12), 2209-2212, 1985 | 208 | 1985 |
Superoxide radical generation, NADPH oxidase activity, and cytochrome P-450 content of rat liver microsomal fractions in an experimental hyperthyroid state: relation to lipid … V FERNANDEZ, X BARRIENTOS, K KIPREOS, A VALENZUELA, ... Endocrinology 117 (2), 496-501, 1985 | 206 | 1985 |
Liver hypermetabolic state after chronic ethanol consumption: hormonal interrelations and pathogenic implications. Y Israel, L Videla, J Bernstein Federation proceedings 34 (11), 2052-2059, 1975 | 199 | 1975 |
The importance of the long-chain polyunsaturated fatty acid n-6/n-3 ratio in development of non-alcoholic fatty liver associated with obesity R Valenzuela, LA Videla Food & function 2 (11), 644-648, 2011 | 198 | 2011 |
Metabolic alterations produced in the liver by chronic ethanol administration. Changes related to energetic parameters of the cell J Bernstein, L Videla, Y Israel Biochemical Journal 134 (2), 515-521, 1973 | 194 | 1973 |
Oxidative stress signaling underlying liver disease and hepatoprotective mechanisms LA Videla World journal of hepatology 1 (1), 72, 2009 | 193 | 2009 |
Long-chain polyunsaturated fatty acids regulation of PPARs, signaling: Relationship to tissue development and aging F Echeverría, M Ortiz, R Valenzuela, LA Videla Prostaglandins, Leukotrienes and Essential Fatty Acids 114, 28-34, 2016 | 189 | 2016 |
Oxidative stress-mediated hepatotoxicity of iron and copper: role of Kupffer cells LA Videla, V Fernández, G Tapia, P Varela Biometals 16, 103-111, 2003 | 187 | 2003 |
Antioxidant activities of lignans and flavonoids M Fauré, E Lissi, R Torres, LA Videla Phytochemistry 29 (12), 3773-3775, 1990 | 171 | 1990 |