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Geoffrey M Lynn
Geoffrey M Lynn
Avidea Technologies
Verified email at jhu.edu - Homepage
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Cited by
Year
In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity
GM Lynn, R Laga, PA Darrah, AS Ishizuka, AJ Balaci, AE Dulcey, ...
Nature biotechnology 33 (11), 1201-1210, 2015
4072015
Protection against malaria at 1 year and immune correlates following PfSPZ vaccination
AS Ishizuka, KE Lyke, A DeZure, AA Berry, TL Richie, FH Mendoza, ...
Nature medicine 22 (6), 614-623, 2016
3682016
Redox catalysis on “naked” silver nanoparticles
G Merga, R Wilson, G Lynn, BH Milosavljevic, D Meisel
The Journal of Physical Chemistry C 111 (33), 12220-12226, 2007
2772007
Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy
G Zhu, GM Lynn, O Jacobson, K Chen, Y Liu, H Zhang, Y Ma, F Zhang, ...
Nature communications 8 (1), 1-15, 2017
2672017
Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens
GM Lynn, C Sedlik, F Baharom, Y Zhu, RA Ramirez-Valdez, VL Coble, ...
Nature biotechnology 38 (3), 320-332, 2020
2422020
Intravenous nanoparticle vaccination generates stem-like TCF1+ neoantigen-specific CD8+ T cells
F Baharom, RA Ramirez-Valdez, KKS Tobin, H Yamane, CA Dutertre, ...
Nature immunology 22 (1), 41-52, 2021
1262021
Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling
KM Quinn, DE Zak, A Costa, A Yamamoto, K Kastenmuller, BJ Hill, ...
The Journal of clinical investigation 125 (3), 1129-1146, 2015
962015
Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment
F Baharom, RA Ramirez-Valdez, A Khalilnezhad, S Khalilnezhad, ...
Cell 185 (23), 4317-4332. e15, 2022
722022
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies
WB Williams, RR Meyerhoff, RJ Edwards, H Li, K Manne, NI Nicely, ...
Cell 184 (11), 2955-2972. e25, 2021
642021
Thermoresponsive polymer nanoparticles co-deliver RSV F trimers with a TLR-7/8 adjuvant
JR Francica, GM Lynn, R Laga, MG Joyce, TJ Ruckwardt, KM Morabito, ...
Bioconjugate Chemistry 27 (10), 2372-2385, 2016
552016
Oncolytic herpes simplex virus immunotherapy for brain tumors: current pitfalls and emerging strategies to overcome therapeutic resistance
SK Totsch, C Schlappi, KD Kang, AS Ishizuka, GM Lynn, B Fox, ...
Oncogene 38 (34), 6159-6171, 2019
542019
Impact of polymer-TLR-7/8 agonist (adjuvant) morphology on the potency and mechanism of CD8 T cell induction
GM Lynn, P Chytil, JR Francica, A Lagová, G Kueberuwa, AS Ishizuka, ...
Biomacromolecules 20 (2), 854-870, 2019
422019
Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates
JR Francica, R Laga, GM Lynn, G Mužíková, L Androvič, B Aussedat, ...
PLoS biology 17 (6), e3000328, 2019
382019
Induction of anti-cancer T cell immunity by in situ vaccination using systemically administered nanomedicines
GM Lynn, R Laga, CM Jewell
Cancer letters 459, 192-203, 2019
282019
Therapeutic cancer vaccines for pediatric malignancies: advances, challenges, and emerging technologies
HE Olsen, GM Lynn, PA Valdes, CD Cerecedo Lopez, AS Ishizuka, ...
Neuro-Oncology Advances 3 (1), vdab027, 2021
162021
Cyclotriphosphazene-based star copolymers as structurally tunable nanocarriers with programmable biodegradability
L Androvic, L Woldrichova, K Jozefjaková, M Pechar, GM Lynn, ...
Macromolecules 54 (7), 3139-3157, 2021
122021
Antigenic competition affects the magnitude and breadth of CD8 T cell immunity following immunization with a nanoparticle neoantigen cancer vaccine
NJ Blobel, A Ramirez-Valdez, AS Ishizuka, GM Lynn, RA Seder
The Journal of Immunology 198 (1_Supplement), 73.20-73.20, 2017
52017
Expression vector delivery system and use thereof for inducing an immune response
R Seder, G Lynn, L Seymour
US Patent 10,799,580, 2020
42020
Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression
RA Ramirez-Valdez, F Baharom, A Khalilnezhad, SC Fussell, ...
Cell reports 42 (6), 2023
32023
Fab-dimerized glycan-reactive antibodies neutralize HIV and are prevalent in humans and rhesus macaques
WB Williams, RR Meyerhoff, RJ Edwards, H Li, NI Nicely, R Henderson, ...
bioRxiv, 2020.06. 30.178921, 2020
32020
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