DNA topoisomerase I and DNA gyrase as targets for TB therapy V Nagaraja, AA Godbole, SR Henderson, A Maxwell Drug discovery today 22 (3), 510-518, 2017 | 113 | 2017 |
Targeting Mycobacterium tuberculosis topoisomerase I by small-molecule inhibitors AA Godbole, W Ahmed, RS Bhat, EK Bradley, S Ekins, V Nagaraja Antimicrobial agents and chemotherapy 59 (3), 1549-1557, 2015 | 64 | 2015 |
Conditional silencing of topoisomerase I gene of Mycobacterium tuberculosis validates its essentiality for cell survival W Ahmed, S Menon, AA Godbole, PV Karthik, V Nagaraja FEMS microbiology letters 353 (2), 116-123, 2014 | 58 | 2014 |
Inhibition of Mycobacterium tuberculosis topoisomerase I by m-AMSA, a eukaryotic type II topoisomerase poison AA Godbole, W Ahmed, RS Bhat, EK Bradley, S Ekins, V Nagaraja Biochemical and Biophysical Research Communications 446 (4), 916-920, 2014 | 43 | 2014 |
Lead selection and characterization of antitubercular compounds using the Nested Chemical Library A Sipos, J Pato, R Szekely, RC Hartkoorn, L Kekesi, L Őrfi, C Szantai-Kis, ... Tuberculosis 95, S200-S206, 2015 | 33 | 2015 |
Stress-responsive and metabolic gene regulation are altered in low S-adenosylmethionine. WAK Ding W, Higgins DP, Yadav DK, Godbole AA, Pukkila-Worley R PLoS Genet 11 (2), 587-597, 2019 | 31* | 2019 |
Characterization of DNA topoisomerase I from Mycobacterium tuberculosis: DNA cleavage and religation properties and inhibition of its activity AA Godbole, MN Leelaram, AG Bhat, P Jain, V Nagaraja Archives of biochemistry and biophysics 528 (2), 197-203, 2012 | 31 | 2012 |
Machine learning and docking models for Mycobacterium tuberculosis topoisomerase I S Ekins, AA Godbole, G Kéri, L Orfi, J Pato, RS Bhat, R Verma, EK Bradley, ... Tuberculosis 103, 52-60, 2017 | 26 | 2017 |
Type IA topoisomerase inhibition by clamp closure MN Leelaram, AG Bhat, AA Godbole, RS Bhat, R Manjunath, V Nagaraja The FASEB Journal 27 (8), 3030-3038, 2013 | 24 | 2013 |
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase G Mori, BS Orena, C Franch, LA Mitchenall, AA Godbole, L Rodrigues, ... Tuberculosis 112, 98-109, 2018 | 13 | 2018 |
A new DNA sensor system for specific and quantitative detection of mycobacteria O Franch, X Han, LB Marcussen, A Givskov, MB Andersen, AA Godbole, ... Nanoscale 11 (2), 587-597, 2019 | 11 | 2019 |
Specific detection of the cleavage activity of mycobacterial enzymes using a quantum dot based DNA nanosensor ML Jepsen, C Harmsen, AA Godbole, V Nagaraja, BR Knudsen, YP Ho Nanoscale 8 (1), 358-364, 2016 | 11 | 2016 |
S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress AA Godbole, S Gopalan, TK Nguyen, AL Munden, DS Lui, MJ Fanelli, ... Elife 12, e79511, 2023 | 5 | 2023 |
Transcriptional regulation of topology modulators and transcription regulators of Mycobacterium tuberculosis S Ghosh, B Padmanabhan, AA Godbole, P Tare, W Ahmed, K Vasu, ... Biochemical and Biophysical Research Communications 475 (3), 257-263, 2016 | 3 | 2016 |
Topoisomerase i from mycobacterium tuberculosis: Dynamics of enzyme function and inhibitor development AA Godbole | | 2020 |