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Adwait Anand Godbole
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DNA topoisomerase I and DNA gyrase as targets for TB therapy
V Nagaraja, AA Godbole, SR Henderson, A Maxwell
Drug discovery today 22 (3), 510-518, 2017
1132017
Targeting Mycobacterium tuberculosis topoisomerase I by small-molecule inhibitors
AA Godbole, W Ahmed, RS Bhat, EK Bradley, S Ekins, V Nagaraja
Antimicrobial agents and chemotherapy 59 (3), 1549-1557, 2015
642015
Conditional silencing of topoisomerase I gene of Mycobacterium tuberculosis validates its essentiality for cell survival
W Ahmed, S Menon, AA Godbole, PV Karthik, V Nagaraja
FEMS microbiology letters 353 (2), 116-123, 2014
582014
Inhibition of Mycobacterium tuberculosis topoisomerase I by m-AMSA, a eukaryotic type II topoisomerase poison
AA Godbole, W Ahmed, RS Bhat, EK Bradley, S Ekins, V Nagaraja
Biochemical and Biophysical Research Communications 446 (4), 916-920, 2014
432014
Lead selection and characterization of antitubercular compounds using the Nested Chemical Library
A Sipos, J Pato, R Szekely, RC Hartkoorn, L Kekesi, L Őrfi, C Szantai-Kis, ...
Tuberculosis 95, S200-S206, 2015
332015
Stress-responsive and metabolic gene regulation are altered in low S-adenosylmethionine.
WAK Ding W, Higgins DP, Yadav DK, Godbole AA, Pukkila-Worley R
PLoS Genet 11 (2), 587-597, 2019
31*2019
Characterization of DNA topoisomerase I from Mycobacterium tuberculosis: DNA cleavage and religation properties and inhibition of its activity
AA Godbole, MN Leelaram, AG Bhat, P Jain, V Nagaraja
Archives of biochemistry and biophysics 528 (2), 197-203, 2012
312012
Machine learning and docking models for Mycobacterium tuberculosis topoisomerase I
S Ekins, AA Godbole, G Kéri, L Orfi, J Pato, RS Bhat, R Verma, EK Bradley, ...
Tuberculosis 103, 52-60, 2017
262017
Type IA topoisomerase inhibition by clamp closure
MN Leelaram, AG Bhat, AA Godbole, RS Bhat, R Manjunath, V Nagaraja
The FASEB Journal 27 (8), 3030-3038, 2013
242013
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase
G Mori, BS Orena, C Franch, LA Mitchenall, AA Godbole, L Rodrigues, ...
Tuberculosis 112, 98-109, 2018
132018
A new DNA sensor system for specific and quantitative detection of mycobacteria
O Franch, X Han, LB Marcussen, A Givskov, MB Andersen, AA Godbole, ...
Nanoscale 11 (2), 587-597, 2019
112019
Specific detection of the cleavage activity of mycobacterial enzymes using a quantum dot based DNA nanosensor
ML Jepsen, C Harmsen, AA Godbole, V Nagaraja, BR Knudsen, YP Ho
Nanoscale 8 (1), 358-364, 2016
112016
S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress
AA Godbole, S Gopalan, TK Nguyen, AL Munden, DS Lui, MJ Fanelli, ...
Elife 12, e79511, 2023
52023
Transcriptional regulation of topology modulators and transcription regulators of Mycobacterium tuberculosis
S Ghosh, B Padmanabhan, AA Godbole, P Tare, W Ahmed, K Vasu, ...
Biochemical and Biophysical Research Communications 475 (3), 257-263, 2016
32016
Topoisomerase i from mycobacterium tuberculosis: Dynamics of enzyme function and inhibitor development
AA Godbole
2020
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