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XIAONAN LI
XIAONAN LI
Senior Clinical Pharmacologist at Takeda
在 takeda.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Liuwei Dihuang Pills alleviate the polycystic ovary syndrome with improved insulin sensitivity through PI3K/Akt signaling pathway
Z Qiu, J Dong, C Xue, X Li, K Liu, B Liu, J Cheng, F Huang
Journal of Ethnopharmacology 250, 111965, 2020
792020
Tanshinone IIA prevents LPS-induced inflammatory responses in mice via inactivation of succinate dehydrogenase in macrophages
Q Liu, Y Zhuang, X Song, Q Niu, Q Sun, X Li, N Li, B Liu, F Huang, Z Qiu
Acta pharmacologica Sinica 42 (6), 987-997, 2021
302021
Modeling combined immunosuppressive and anti-inflammatory effects of dexamethasone and naproxen in rats predicts the steroid-sparing potential of naproxen
X Li, DC DuBois, D Song, RR Almon, WJ Jusko, X Chen
Drug Metabolism and Disposition 45 (7), 834-845, 2017
292017
Stereoselective pharmacokinetic and metabolism studies of 20 (S)-and 20 (R)-ginsenoside Rg3 epimers in rat plasma by liquid chromatography-electrospray ionization mass spectrometry
M Peng, X Li, T Zhang, Y Ding, Y Yi, J Le, Y Yang, X Chen
Journal of Pharmaceutical and Biomedical Analysis 121, 215-224, 2016
292016
Assessment of the Kochak-Benet equation for hepatic clearance for the parallel-tube model: relevance of classic clearance concepts in PK and PBPK
WJ Jusko, X Li
The AAPS journal 24, 1-7, 2022
182022
Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes
T Li, N Li, Q Guo, H Ji, D Zhao, S Xie, X Li, Z Qiu, D Han, X Chen, Q You
European journal of drug metabolism and pharmacokinetics 36, 249-256, 2011
182011
Regulation on citrate influx and metabolism through inhibiting SLC13A5 and ACLY: a novel mechanism mediating the therapeutic effects of curcumin on NAFLD
Q Sun, Q Niu, Y Guo, Y Zhuang, X Li, J Liu, N Li, Z Li, F Huang, Z Qiu
Journal of Agricultural and Food Chemistry 69 (31), 8714-8725, 2021
172021
Exposure‐Response Analysis of Vamorolone (VBP15) in Boys With Duchenne Muscular Dystrophy
X Li, LS Conklin, J van den Anker, EP Hoffman, PR Clemens, WJ Jusko
The Journal of Clinical Pharmacology 60 (10), 1385-1396, 2020
162020
Assessing liver-to-plasma partition coefficients and in silico calculation methods: when does the hepatic model matter in PBPK?
X Li, WJ Jusko
Drug Metabolism and Disposition 50 (12), 1501-1512, 2022
122022
Inhibitory and inductive effects of Corydalis saxicola Bunting total alkaloids (CSBTA) on cytochrome P450s in rats
J Yu, Q Liu, X Lu, X Li, N Li, B Liu, F Huang, Z Qiu
Phytotherapy research 32 (9), 1818-1827, 2018
122018
Physiologically based pharmacokinetic modeling involving nonlinear plasma and tissue binding: Application to prednisolone and prednisone in rats
X Li, DC DuBois, RR Almon, WJ Jusko
Journal of Pharmacology and Experimental Therapeutics 375 (2), 385-396, 2020
112020
Development and validation of a simple and reliable LC-MS/MS method for the determination of acetazolamide, an effective carbonic anhydrase inhibitor, in plasma and its …
X Li, N Li, C Wang, S Deng, X Sun, W Zhang, W Gao, D Zhao, Y Lu, ...
Drug research, 499-504, 2014
112014
Modeling sex differences in pharmacokinetics, pharmacodynamics, and disease progression effects of naproxen in rats with collagen-induced arthritis
X Li, DC DuBois, RR Almon, WJ Jusko
Drug Metabolism and Disposition 45 (5), 484-491, 2017
102017
Investigation of the role of organic cation transporter 2 (OCT2) in the renal transport of guanfacine, a selective α2A-adrenoreceptor agonist
X Li, X Sun, J Chen, Y Lu, Y Zhang, C Wang, J Li, Q Zhang, D Zhao, ...
Xenobiotica 45 (1), 88-94, 2015
102015
Pharmacokinetics and metabolism of H3B-6545, a selective estrogen receptor covalent antagonist, in dog plasma by liquid chromatography combined with electrospray ionization …
Y Ge, Y Zhang, X Li, Y Yu, Q Liu
Journal of Pharmaceutical and Biomedical Analysis 172, 189-199, 2019
62019
Effect of disease-related changes in plasma albumin on the pharmacokinetics of naproxen in male and female arthritic rats
X Li, DC DuBois, RR Almon, WJ Jusko
Drug Metabolism and Disposition 45 (5), 476-483, 2017
62017
Pharmacokinetic evaluation of β-caryophyllene alcohol in rats and beagle dogs
J He, S Zhou, X Li, C Wang, Y Yu, X Chen, Y Lu
Xenobiotica 48 (8), 845-850, 2018
52018
Exploring the pharmacokinetic mysteries of the liver: application of series compartment models of hepatic elimination
X Li, WJ Jusko
Drug Metabolism and Disposition 51 (5), 618-628, 2023
42023
Interactions of tofacitinib and dexamethasone on lymphocyte proliferation
R Yu, X Li, DC DuBois, RR Almon, Y Cao, WJ Jusko
Pharmaceutical Research 37, 1-9, 2020
42020
Development and validation of a simple, sensitive and accurate LC‐MS/MS method for the determination of guanfacine, a selective α2A‐adrenergicreceptor …
X Li, N Li, X Sun, W Yang, Y Dai, J Xu, W Zhang, C Wang, S Wang, ...
Biomedical Chromatography 27 (12), 1708-1713, 2013
42013
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