| A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells DJ Trader, S Simanski, T Kodadek Journal of the American Chemical Society 137 (19), 6312-6319, 2015 | 85 | 2015 |
| BRD4 phosphorylation regulates HPV E2-mediated viral transcription, origin replication, and cellular MMP-9 expression SY Wu, DS Nin, AY Lee, S Simanski, T Kodadek, CM Chiang Cell reports 16 (6), 1733-1748, 2016 | 78 | 2016 |
| Utility of redundant combinatorial libraries in distinguishing high and low quality screening hits TM Doran, Y Gao, K Mendes, S Dean, S Simanski, T Kodadek ACS combinatorial science 16 (6), 259-270, 2014 | 71 | 2014 |
| Establishment of a suite of assays that support the discovery of proteasome stimulators DJ Trader, S Simanski, P Dickson, T Kodadek Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (4), 892-899, 2017 | 60 | 2017 |
| Redundant ubiquitin ligase activities regulate wee1 degradation and mitotic entry A Smith, S Simanski, M Fallahi, NG Ayad Cell Cycle 6 (22), 2795-2799, 2007 | 59 | 2007 |
| The anaphase promoting complex induces substrate degradation during neuronal differentiation D Harmey, A Smith, S Simanski, CZ Moussa, NG Ayad Journal of biological chemistry 284 (7), 4317-4323, 2009 | 36 | 2009 |
| Expression of a Porphyromonas gingivalis hemagglutinin on the surface of a Salmonella vaccine vector R Isoda, SP Simanski, L Pathangey, AES Stone, TA Brown Vaccine 25 (1), 117-126, 2007 | 31 | 2007 |
| Activation domain-dependent degradation of somatic Wee1 kinase L Owens, S Simanski, C Squire, A Smith, J Cartzendafner, V Cavett, ... Journal of biological chemistry 285 (9), 6761-6769, 2010 | 28 | 2010 |
| Casein kinase 1δ-dependent Wee1 protein degradation C Penas, V Ramachandran, S Simanski, C Lee, F Madoux, RJ Rahaim, ... Journal of Biological Chemistry 289 (27), 18893-18903, 2014 | 27 | 2014 |
| Screening one bead one compound libraries against serum using a flow cytometer: Determination of the minimum antibody concentration required for ligand discovery O Erharuyi, S Simanski, PJ McEnaney, T Kodadek Bioorganic & medicinal chemistry letters 28 (16), 2773-2778, 2018 | 23 | 2018 |
| An ultra-high throughput cell-based screen for wee1 degradation inhibitors F Madoux, S Simanski, P Chase, JK Mishra, WR Roush, NG Ayad, ... Journal of biomolecular screening 15 (8), 907-917, 2010 | 21 | 2010 |
| Discovery of phosphorylated peripherin as a major humoral autoantigen in type 1 diabetes mellitus TM Doran, J Morimoto, S Simanski, EJ Koesema, LF Clark, K Pels, ... Cell chemical biology 23 (5), 618-628, 2016 | 19 | 2016 |
| Discovery of native autoantigens via antigen surrogate technology: application to type 1 diabetes TM Doran, S Simanski, T Kodadek ACS Chemical Biology 10 (2), 401-412, 2015 | 17 | 2015 |
| Physical and functional analysis of the putative Rpn13 inhibitor RA190 P Dickson, D Abegg, E Vinogradova, J Takaya, H An, S Simanski, ... Cell chemical biology 27 (11), 1371-1382. e6, 2020 | 16 | 2020 |
| High affinity binding of conformationally constrained synthetic oligomers to an antigen-specific antibody: Discovery of a diagnostically useful synthetic ligand for murine Type … TM Doran, Y Gao, S Simanski, P McEnaney, T Kodadek Bioorganic & medicinal chemistry letters 25 (21), 4910-4917, 2015 | 13 | 2015 |
| Mechanistic studies of the multiple myeloma and melanoma cell-selective toxicity of the Rpn13-binding peptoid KDT-11 P Dickson, S Simanski, JM Ngundu, T Kodadek Cell chemical biology 27 (11), 1383-1395. e5, 2020 | 11 | 2020 |
| Antibody biomarker for de novo Parkinson disease: attempted validation N Feng, S Simanski, K Islam, LS Hynan, T Kodadek, DC German npj Parkinson's Disease 4 (1), 28, 2018 | 10 | 2018 |
| Reliable diagnosis of murine type 1 diabetes using a panel of autoantigens and “antigen surrogates” mounted onto a liquid array TM Doran, J Morimoto, S Simanski, PJ McEnaney, T Kodadek Molecular bioSystems 11 (11), 3156-3163, 2015 | 5 | 2015 |
| Wee1 degradation inhibitors WR Roush, R Rahaim, M Bibian US Patent 9,493,464, 2016 | 4 | 2016 |
| Small molecule inhibitors of Wee1 degradation and mitotic entry F Madoux, J Mishra, BA Mercer, N Ayad, W Roush, P Hodder, HR Rosen Probe Reports from the NIH Molecular Libraries Program [Internet], 2011 | 4 | 2011 |
Franck MadouxAssociate Director, AmgenVerified email at amgen.com
