Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines K Nakatani, DA Thompson, A Barthel, H Sakaue, W Liu, RJ Weigel, ... Journal of Biological Chemistry 274 (31), 21528-21532, 1999 | 641 | 1999 |
1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells. K Hara, K Yonezawa, H Sakaue, A Ando, K Kotani, T Kitamura, ... Proceedings of the National Academy of Sciences 91 (16), 7415-7419, 1994 | 539 | 1994 |
Requirement of atypical protein kinase Cλ for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes K Kotani, W Ogawa, M Matsumoto, T Kitamura, H Sakaue, Y Hino, ... Molecular and cellular biology 18 (12), 6971-6982, 1998 | 480 | 1998 |
Involvement of phosphoinositide 3‐kinase in insulin‐or IGF‐1‐induced membrane ruffling. K Kotani, K Yonezawa, K Hara, H Ueda, Y Kitamura, H Sakaue, A Ando, ... The EMBO journal 13 (10), 2313-2321, 1994 | 431 | 1994 |
Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo H Inoue, W Ogawa, M Ozaki, S Haga, M Matsumoto, K Furukawa, ... Nature medicine 10 (2), 168-174, 2004 | 424 | 2004 |
Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport T Kitamura, W Ogawa, H Sakaue, Y Hino, S Kuroda, M Takata, ... Molecular and cellular biology 18 (7), 3708-3717, 1998 | 401 | 1998 |
A role for phosphoinositide 3-kinase in bacterial invasion K Ireton, B Payrastre, H Chap, W Ogawa, H Sakaue, M Kasuga, P Cossart Science 274 (5288), 780-782, 1996 | 397 | 1996 |
Role of Krüppel-like factor 15 (KLF15) in transcriptional regulation of adipogenesis T Mori, H Sakaue, H Iguchi, H Gomi, Y Okada, Y Takashima, K Nakamura, ... Journal of Biological Chemistry 280 (13), 12867-12875, 2005 | 395 | 2005 |
Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation MW Greene, H Sakaue, L Wang, DR Alessi, RA Roth Journal of Biological Chemistry 278 (10), 8199-8211, 2003 | 263 | 2003 |
Identification of a human Akt3 (protein kinase B γ) which contains the regulatory serine phosphorylation site K Nakatani, H Sakaue, DA Thompson, RJ Weigel, RA Roth Biochemical and biophysical research communications 257 (3), 906-910, 1999 | 263 | 1999 |
Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice T Uchida, T Nakamura, N Hashimoto, T Matsuda, K Kotani, H Sakaue, ... Nature medicine 11 (2), 175-182, 2005 | 261 | 2005 |
Changes in the anterior chamber configuration after small-incision cataract surgery with posterior chamber intraocular lens implantation Y Kurimoto, M Park, H Sakaue, T Kondo American journal of ophthalmology 124 (6), 775-780, 1997 | 250 | 1997 |
Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance S Nishimoto, D Fukuda, Y Higashikuni, K Tanaka, Y Hirata, C Murata, ... Science advances 2 (3), e1501332, 2016 | 245 | 2016 |
Requirement for phosphoinositide 3-kinase in insulin-stimulated GLUT4 translocation in 3T3-L1 adipocytes K KOtani, AJ Carozzi, H Sakaue, K Hara, LJ Robinson, SF Clark, ... Biochemical and biophysical research communications 209 (1), 343-348, 1995 | 198 | 1995 |
Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver K Miyake, W Ogawa, M Matsumoto, T Nakamura, H Sakaue, M Kasuga The Journal of clinical investigation 110 (10), 1483-1491, 2002 | 189 | 2002 |
Posttranscriptional control of adipocyte differentiation through activation of phosphoinositide 3-kinase H Sakaue, W Ogawa, M Matsumoto, S Kuroda, M Takata, T Sugimoto, ... Journal of Biological Chemistry 273 (44), 28945-28952, 1998 | 176 | 1998 |
Requirement of fibroblast growth factor 10 in development of white adipose tissue H Sakaue, M Konishi, W Ogawa, T Asaki, T Mori, M Yamasaki, M Takata, ... Genes & development 16 (8), 908-912, 2002 | 169 | 2002 |
Phosphoinositide 3-kinase is required for insulin-induced but not for growth hormone-or hyperosmolarity-induced glucose uptake in 3T3-L1 adipocytes H Sakaue, W Ogawa, M Takata, S Kuroda, K Kotani, M Matsumoto, ... Molecular Endocrinology 11 (10), 1552-1562, 1997 | 155 | 1997 |
Adipose Tissue–Specific Regulation of Angiotensinogen in Obese Humans and Mice: Impact of Nutritional Status and Adipocyte Hypertrophy S Yasue, H Masuzaki, S Okada, T Ishii, C Kozuka, T Tanaka, J Fujikura, ... American journal of hypertension 23 (4), 425-431, 2010 | 150 | 2010 |
Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and … M Matsumoto, W Ogawa, K Teshigawara, H Inoue, K Miyake, H Sakaue, ... Diabetes 51 (6), 1672-1680, 2002 | 147 | 2002 |