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Jakob Kaeppler
Jakob Kaeppler
Verified email at oncology.ox.ac.uk
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Cited by
Cited by
Year
ADAM17 substrate release in proximal tubule drives kidney fibrosis
E Kefaloyianni, ML Muthu, J Kaeppler, X Sun, V Sabbisetti, A Chalaris, ...
JCI insight 1 (13), 2016
1262016
Type I IFN protects cancer cells from CD8+ T cell–mediated cytotoxicity after radiation
J Chen, Y Cao, B Markelc, J Kaeppler, JAF Vermeer, RJ Muschel
The Journal of clinical investigation 129 (10), 4224-4238, 2019
1112019
Altered MCM protein levels and autophagic flux in aged and systemic sclerosis dermal fibroblasts
VI Dumit, V Küttner, J Käppler, S Piera-Velazquez, SA Jimenez, ...
Journal of Investigative Dermatology 134 (9), 2321-2330, 2014
592014
Abnormal morphology biases hematocrit distribution in tumor vasculature and contributes to heterogeneity in tissue oxygenation
MO Bernabeu, J Köry, JA Grogan, B Markelc, A Beardo, M d’Avezac, ...
Proceedings of the National Academy of Sciences 117 (45), 27811-27819, 2020
432020
Extracting 3D vascular structures from microscopy images using convolutional recurrent networks
R Bates, B Irving, B Markelc, J Kaeppler, R Muschel, V Grau, JA Schnabel
arXiv preprint arXiv:1705.09597, 2017
272017
Multiscale topology characterizes dynamic tumor vascular networks
BJ Stolz, J Kaeppler, B Markelc, F Braun, F Lipsmeier, RJ Muschel, ...
Science Advances 8 (23), eabm2456, 2022
242022
Segmentation of vasculature from fluorescently labeled endothelial cells in multi-photon microscopy images
R Bates, B Irving, B Markelc, J Kaeppler, G Brown, RJ Muschel, M Brady, ...
IEEE transactions on medical imaging 38 (1), 1-10, 2017
222017
STING-dependent interferon-λ1 induction in HT29 cells, a human colorectal cancer cell line, after gamma-radiation
J Chen, B Markelc, J Kaeppler, VML Ogundipe, Y Cao, WG McKenna, ...
International Journal of Radiation Oncology* Biology* Physics 101 (1), 97-106, 2018
182018
Functional parameters derived from magnetic resonance imaging reflect vascular morphology in preclinical tumors and in human liver metastases
P Kannan, WW Kretzschmar, H Winter, D Warren, R Bates, PD Allen, ...
Clinical Cancer Research 24 (19), 4694-4704, 2018
172018
Attenuation of the hypoxia inducible factor pathway after oncolytic adenovirus infection coincides with decreased vessel perfusion
I Yousaf, J Kaeppler, S Frost, LW Seymour, EJ Jacobus
Cancers 12 (4), 851, 2020
122020
ADAM17 substrate release in proximal tubule drives kidney fibrosis. JCI Insight 1 (13)
E Kefaloyianni, ML Muthu, J Kaeppler, X Sun, V Sabbisetti, A Chalaris, ...
72016
Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models
JR Kaeppler, J Chen, M Buono, J Vermeer, P Kannan, WC Cheng, ...
EMBO reports 23 (9), e53221, 2022
62022
Radiation resistant cancer cells enhance the survival and resistance of sensitive cells in prostate spheroids
P Kannan, M Paczkowski, A Miar, J Owen, WW Kretzschmar, S Lucotti, ...
BioRxiv, 564724, 2019
62019
Enhanced perfusion following exposure to radiotherapy: a theoretical investigation
J Köry, V Narain, BJ Stolz, J Kaeppler, B Markelc, RJ Muschel, PK Maini, ...
PLOS Computational Biology 20 (2), e1011252, 2024
2024
Endothelial apoptosis after ionizing radiation mainly occurs in non-perfused vessels leaving vascular function intact
B Markelc, J Kaeppler, M Buono, J Chen, W Cheng, J Thompson, M Hill, ...
FEBS OPEN BIO 11, 93-94, 2021
2021
A lineage-tracing tool to map the fate of post-hypoxic H1299 NSCLC tumour cells
JAF Vermeer, J Ient, B Markelc, J Kaeppler, LMO Barbeau, AJ Groot, ...
bioRxiv, 2020.03. 03.974857, 2020
2020
Investigation of the tumour vascular response to single and fractionated irradiation
JR Kaeppler
University of Oxford, 2019
2019
Resemblances between scleroderma and ageing in skin fibroblasts
VI Dumit, V Kuettner, J Kaeppler, S Piera-Velazquez, SA Jimenez, ...
JOURNAL OF INVESTIGATIVE DERMATOLOGY 133, S156-S156, 2013
2013
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