Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies Z Sebestyen, I Prinz, J Déchanet-Merville, B Silva-Santos, J Kuball Nature reviews Drug discovery 19 (3), 169-184, 2020 | 323 | 2020 |
Lipid rafts and the local density of ErbB proteins influence the biological role of homo-and heteroassociations of ErbB2 P Nagy, G Vereb, Z Sebestyén, G Horváth, SJ Lockett, S Damjanovich, ... Journal of cell science 115 (22), 4251-4262, 2002 | 256 | 2002 |
γδT cells elicited by CMV reactivation after allo-SCT cross-recognize CMV and leukemia W Scheper, S van Dorp, S Kersting, F Pietersma, C Lindemans, S Hol, ... Leukemia 27 (6), 1328-1338, 2013 | 221 | 2013 |
Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma E Drent, RWJ Groen, WA Noort, M Themeli, JJL van Bueren, PWHI Parren, ... haematologica 101 (5), 616, 2016 | 173 | 2016 |
Redirecting αβT cells against cancer cells by transfer of a broadly tumor-reactive γδT-cell receptor V Marcu-Malina, S Heijhuurs, M van Buuren, L Hartkamp, S Strand, ... Blood, The Journal of the American Society of Hematology 118 (1), 50-59, 2011 | 149 | 2011 |
RhoB mediates phosphoantigen recognition by Vγ9Vδ2 T cell receptor Z Sebestyen, W Scheper, A Vyborova, S Gu, Z Rychnavska, M Schiffler, ... Cell reports 15 (9), 1973-1985, 2016 | 145 | 2016 |
Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction S Dornan, Z Sebestyen, J Gamble, P Nagy, A Bodnar, L Alldridge, S Doe, ... Journal of Biological Chemistry 277 (3), 1912-1918, 2002 | 134 | 2002 |
T cell receptor gene therapy: strategies for optimizing transgenic TCR pairing C Govers, Z Sebestyén, M Coccoris, RA Willemsen, R Debets Trends in molecular medicine 16 (2), 77-87, 2010 | 130 | 2010 |
Human TCR that incorporate CD3ζ induce highly preferred pairing between TCRα and β chains following gene transfer Z Sebestyen, E Schooten, T Sals, I Zaldivar, E San Jose, B Alarcon, ... The Journal of Immunology 180 (11), 7736-7746, 2008 | 107 | 2008 |
γ9 and δ2CDR3 domains regulate functional avidity of T cells harboring γ9δ2TCRs C Gründer, S van Dorp, S Hol, E Drent, T Straetemans, S Heijhuurs, ... Blood, The Journal of the American Society of Hematology 120 (26), 5153-5162, 2012 | 98 | 2012 |
Long wavelength fluorophores and cell‐by‐cell correction for autofluorescence significantly improves the accuracy of flow cytometric energy transfer measurements on a dual … Z Sebestyén, P Nagy, G Horváth, G Vámosi, R Debets, JW Gratama, ... Cytometry: The Journal of the International Society for Analytical Cytology …, 2002 | 94 | 2002 |
A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells RCG de Bruin, JP Veluchamy, SM Lougheed, FL Schneiders, ... Oncoimmunology 7 (1), e1375641, 2018 | 79 | 2018 |
Cellular immunotherapy on primary multiple myeloma expanded in a 3D bone marrow niche model MVJ Braham, MC Minnema, T Aarts, Z Sebestyen, T Straetemans, ... Oncoimmunology 7 (6), e1434465, 2018 | 68 | 2018 |
GMP-grade manufacturing of T cells engineered to express a defined γδTCR T Straetemans, GJJ Kierkels, R Doorn, K Jansen, S Heijhuurs, ... Frontiers in immunology 9, 1062, 2018 | 67 | 2018 |
Cost‐effectiveness analysis of intensity‐modulated radiation therapy with normal and hypofractionated schemes for the treatment of localised prostate cancer AT Zemplényi, Z Kaló, G Kovacs, R Farkas, T Beöthe, D Bányai, ... European Journal of Cancer Care 27 (1), e12430, 2018 | 66 | 2018 |
Uncovering the mode of action of engineered T cells in patient cancer organoids JF Dekkers, M Alieva, A Cleven, F Keramati, AKL Wezenaar, EJ van Vliet, ... Nature biotechnology 41 (1), 60-69, 2023 | 65 | 2023 |
Associations of ErbB2, β1-integrin and lipid rafts on Herceptin (Trastuzumab) resistant and sensitive tumor cell lines MM Mocanu, Z Fazekas, M Petrás, P Nagy, Z Sebestyén, J Isola, J Tímár, ... Cancer letters 227 (2), 201-212, 2005 | 64 | 2005 |
γ9δ2T cell diversity and the receptor interface with tumor cells A Vyborova, DX Beringer, D Fasci, F Karaiskaki, E van Diest, L Kramer, ... The Journal of clinical investigation 130 (9), 4637-4651, 2020 | 61 | 2020 |
Applications of fluorescence resonance energy transfer for mapping biological membranes J Szöllosi, P Nagy, Z Sebestyén, S Damjanovich, JW Park, L Mátyus Reviews in Molecular Biotechnology 82 (3), 251-266, 2002 | 58 | 2002 |
Hunting for clinical translation with innate-like immune cells and their receptors W Scheper, C Gründer, T Straetemans, Z Sebestyen, J Kuball Leukemia 28 (6), 1181-1190, 2014 | 57 | 2014 |