| Insights into the mechanism and catalysis of the native chemical ligation reaction ECB Johnson, SBH Kent Journal of the American Chemical Society 128 (20), 6640-6646, 2006 | 724 | 2006 |
| Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, ... Nature medicine 26 (5), 769-780, 2020 | 633 | 2020 |
| Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level ECB Johnson, EK Carter, EB Dammer, DM Duong, ES Gerasimov, Y Liu, ... Nature neuroscience 25 (2), 213-225, 2022 | 238 | 2022 |
| Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice DB Dubal, L Zhu, PE Sanchez, K Worden, L Broestl, E Johnson, K Ho, ... Journal of Neuroscience 35 (6), 2358-2371, 2015 | 205 | 2015 |
| Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease L Higginbotham, L Ping, EB Dammer, DM Duong, M Zhou, M Gearing, ... Science advances 6 (43), eaaz9360, 2020 | 200 | 2020 |
| Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease ECB Johnson, EB Dammer, DM Duong, L Yin, M Thambisetty, ... Molecular neurodegeneration 13, 1-22, 2018 | 172 | 2018 |
| Towards the total chemical synthesis of integral membrane proteins: a general method for the synthesis of hydrophobic peptide-αthioester building blocks ECB Johnson, SBH Kent Tetrahedron letters 48 (10), 1795-1799, 2007 | 104 | 2007 |
| A designer ligand specific for Kv1. 3 channels from a scorpion neurotoxin-based library Z Takacs, M Toups, A Kollewe, E Johnson, LG Cuello, G Driessens, ... Proceedings of the National Academy of Sciences 106 (52), 22211-22216, 2009 | 88 | 2009 |
| Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study E Morenas-Rodríguez, Y Li, B Nuscher, N Franzmeier, C Xiong, ... The Lancet Neurology 21 (4), 329-341, 2022 | 83 | 2022 |
| Modular total chemical synthesis of a human immunodeficiency virus type 1 protease ECB Johnson, E Malito, Y Shen, D Rich, WJ Tang, SBH Kent Journal of the American Chemical Society 129 (37), 11480-11490, 2007 | 81 | 2007 |
| Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer’s disease M Zhou, RU Haque, EB Dammer, DM Duong, L Ping, ECB Johnson, ... Clinical proteomics 17, 1-14, 2020 | 56 | 2020 |
| Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer’s … ECB Johnson, K Ho, GQ Yu, M Das, PE Sanchez, B Djukic, I Lopez, X Yu, ... Molecular neurodegeneration 15, 1-26, 2020 | 55 | 2020 |
| Identification of conserved proteomic networks in neurodegenerative dementia V Swarup, TS Chang, DM Duong, EB Dammer, J Dai, JJ Lah, ... Cell reports 31 (12), 2020 | 55 | 2020 |
| Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease J Dai, ECB Johnson, EB Dammer, DM Duong, M Gearing, JJ Lah, ... Frontiers in molecular neuroscience 11, 454, 2018 | 55 | 2018 |
| Multi-platform proteomic analysis of Alzheimer’s disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome EB Dammer, L Ping, DM Duong, ES Modeste, NT Seyfried, JJ Lah, ... Alzheimer's research & therapy 14 (1), 174, 2022 | 54 | 2022 |
| Total chemical synthesis, folding, and assay of a small protein on a water‐compatible solid support ECB Johnson, T Durek, SBH Kent Angewandte Chemie 118 (20), 3361-3365, 2006 | 52 | 2006 |
| Studies on the insolubility of a transmembrane peptide from signal peptide peptidase ECB Johnson, SBH Kent Journal of the American Chemical Society 128 (22), 7140-7141, 2006 | 38 | 2006 |
| Increasing the receptor tyrosine kinase EphB2 prevents amyloid-β-induced depletion of cell surface glutamate receptors by a mechanism that requires the PDZ-binding motif of … T Miyamoto, D Kim, JA Knox, E Johnson, L Mucke Journal of Biological Chemistry 291 (4), 1719-1734, 2016 | 34 | 2016 |
| Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease ECB Johnson, S Bian, RU Haque, EK Carter, CM Watson, BA Gordon, ... Nature medicine 29 (8), 1979-1988, 2023 | 30 | 2023 |
| Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease PR Millar, PH Luckett, BA Gordon, TLS Benzinger, SE Schindler, ... Neuroimage 256, 119228, 2022 | 29 | 2022 |
