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Francois Gaudreault
Francois Gaudreault
Head Clinical Pharmacology | Apellis Pharmaceuticals
Verified email at apellis.com
Title
Cited by
Cited by
Year
New 1, 2, 3, 4-tetrahydropyrrolo [3, 4-b] indole derivatives as selective CB2 receptor agonists
D Pagé, H Yang, W Brown, C Walpole, M Fleurent, M Fyfe, F Gaudreault, ...
Bioorganic & medicinal chemistry letters 17 (22), 6183-6187, 2007
732007
Trial of anti-BDCA2 antibody litifilimab for cutaneous lupus erythematosus
VP Werth, RA Furie, J Romero-Diaz, S Navarra, K Kalunian, ...
New England Journal of Medicine 387 (4), 321-331, 2022
602022
Attenuation of ketamine-induced impairment in verbal learning and memory in healthy volunteers by the AMPA receptor potentiator PF-04958242
M Ranganathan, N DeMartinis, B Huguenel, F Gaudreault, MM Bednar, ...
Molecular psychiatry 22 (11), 1633-1640, 2017
432017
Systems approach reveals photosensitivity and PER 2 level as determinants of clock‐modulator efficacy
DW Kim, C Chang, X Chen, AC Doran, F Gaudreault, T Wager, ...
Molecular Systems Biology 15 (7), e8838, 2019
352019
A population pharmacokinetic model for the complex systemic absorption of ropivacaine after femoral nerve block in patients undergoing knee surgery
F Gaudreault, P Drolet, M Fallaha, F Varin
Journal of pharmacokinetics and pharmacodynamics 39, 635-642, 2012
242012
The reliability of the current perception threshold in volunteers and its applicability in a clinical setting
F Gaudreault, P Drolet, M Fallaha, F Varin
Anesthesia & Analgesia 120 (3), 678-683, 2015
222015
OP0193 BIIB059, a humanized monoclonal antibody targeting BDCA2 on plasmacytoid dendritic cells (pDC), shows dose-related efficacy in the phase 2 LILAC study in patients (pts …
V Werth, R Furie, J Romero-Diaz, S Navarra, K Kalunian, ...
Annals of the Rheumatic Diseases 79 (Suppl 1), 120-121, 2020
192020
High-performance liquid chromatography using UV detection for the simultaneous quantification of ropivacaine and bupivacaine in human plasma
F Gaudreault, P Drolet, F Varin
Therapeutic drug monitoring 31 (6), 753-757, 2009
172009
Modeling the anesthetic effect of ropivacaine after a femoral nerve block in orthopedic patients: a population pharmacokinetic–pharmacodynamic analysis
F Gaudreault, P Drolet, M Fallaha, F Varin
Anesthesiology 122 (5), 1010-1020, 2015
102015
BIIB059, a humanized monoclonal antibody targeting blood dendritic cell antigen 2 on plasmacytoid dendritic cells, shows dose-related efficacy in a phase 2 study in …
V Werth, R Furie, J Romero-Diaz, S Navarra, K Kalunian, ...
ARTHRITIS & RHEUMATOLOGY 72, 2020
92020
The safety and efficacy of PF-04958242 in age-related sensorineural hearing loss: a randomized clinical trial
MM Bednar, N DeMartinis, A Banerjee, S Bowditch, F Gaudreault, ...
JAMA Otolaryngology–Head & Neck Surgery 141 (7), 607-613, 2015
92015
Investigation of CYP3A induction by PF‐05251749 in early clinical development: comparison of linear slope physiologically based pharmacokinetic prediction and biomarker response
J Lin, F Gaudreault, N Johnson, Z Lin, P Nouri, TC Goosen, ...
Clinical and Translational Science 15 (9), 2184-2194, 2022
12022
Quantitative understanding of the longitudinal relationship between short-term MRI outcomes and long-term clinical outcomes measures in multiple sclerosis
M Wiens, AH Maghzi, N Mangal, KK Muralidharan, H Naik, J French, ...
MULTIPLE SCLEROSIS JOURNAL 27 (2_ SUPPL), 738-739, 2021
12021
Prospective application and validation of a systems pharmacology model to guide the clinical development of PF-05251749: a casein kinase 1 (CK1) inhibitor
F Gaudreault, A Simen, E Pickering, D Volfson, T Wager, J Kim, KA Kim, ...
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 45, S14-S15, 2018
12018
Pharmacométrie de la ropivacaïne suivant l'anesthésie locorégionale chez les patients orthopédiques: Caractérisation de l'intensité et de la durée du bloc sensitif
F Gaudreault
Universite de Montreal (Canada), 2014
12014
Methods of treating cutaneous lupus erythematosus and systemic lupus erythematosus
F Gaudreault, H Naik
US Patent App. 18/038,911, 2024
2024
MODEL-INFORMED DEVELOPMENT OF BIIB104 IN SCHIZOPHRENIA: A POPPK APPROACH TO SUPPORT ENROLMENT OF JAPANESE SUBJECTS IN PHASE 2
F Gaudreault, M Rooney, E Fossale, E Arce, C Shaffer
CLINICAL PHARMACOLOGY & THERAPEUTICS 109, S11-S12, 2021
2021
FRI0204 SAFETY, TOLERABILITY, PHARMACOKINETIC AND PHARMACODYNAMIC EFFECT OF BIIB059, A MONOCLONAL ANTIBODY TARGETING BDCA2 FOLLOWING ADMINISTRATION OF SUBCUTANEOUS SINGLE DOSES …
C Musselli, F Gaudreault, H Naik, H Carroll, A Sharma, X Huang, ...
Annals of the Rheumatic Diseases 78 (Suppl 2), 781-781, 2019
2019
Hitting the Moving Target in Circadian Rhythm: The Application of Systems Pharmacology Model in the Development of a CK1 Inhibitor
C Chang, F Gaudreault, A Simen, T Wager, J Kim, KA Kim, T Park, ...
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 44, S76-S76, 2017
2017
Safety, Pharmacokinetics (PK) and Clinical Effects of PF-04958242, an alpha-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Positive Allosteric Modulator (PAM) in …
B Evans, N DeMartinis, F Gaudreault, J Mancuso, L Zumpano, D Walling, ...
NEUROPSYCHOPHARMACOLOGY 41, S415-S415, 2016
2016
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