| PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors S Takae, K Miyata, M Oba, T Ishii, N Nishiyama, K Itaka, Y Yamasaki, ... Journal of the American Chemical Society 130 (18), 6001-6009, 2008 | 445 | 2008 |
| Polyplexes from poly (aspartamide) bearing 1, 2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible … K Miyata, M Oba, M Nakanishi, S Fukushima, Y Yamasaki, H Koyama, ... Journal of the American Chemical Society 130 (48), 16287-16294, 2008 | 379 | 2008 |
| Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery S Matsumoto, RJ Christie, N Nishiyama, K Miyata, A Ishii, M Oba, ... Biomacromolecules 10 (1), 119-127, 2009 | 374 | 2009 |
| Charge‐conversion ternary polyplex with endosome disruption moiety: a technique for efficient and safe gene delivery Y Lee, K Miyata, M Oba, T Ishii, S Fukushima, M Han, H Koyama, ... Angewandte Chemie 120 (28), 5241-5244, 2008 | 272 | 2008 |
| Cyclic RGD Peptide-Conjugated Polyplex Micelles as a Targetable Gene Delivery System Directed to Cells Possessing αvβ3 and αvβ5 Integrins M Oba, S Fukushima, N Kanayama, K Aoyagi, N Nishiyama, H Koyama, ... Bioconjugate chemistry 18 (5), 1415-1423, 2007 | 245 | 2007 |
| Spontaneous formation of nanosized unilamellar polyion complex vesicles with tunable size and properties Y Anraku, A Kishimura, M Oba, Y Yamasaki, K Kataoka Journal of the American Chemical Society 132 (5), 1631-1636, 2010 | 243 | 2010 |
| Odd–even effect of repeating aminoethylene units in the side chain of N-substituted polyaspartamides on gene transfection profiles H Uchida, K Miyata, M Oba, T Ishii, T Suma, K Itaka, N Nishiyama, ... Journal of the American Chemical Society 133 (39), 15524-15532, 2011 | 227 | 2011 |
| Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer T Nomoto, S Fukushima, M Kumagai, K Machitani, Arnida, Y Matsumoto, ... Nature communications 5 (1), 3545, 2014 | 188 | 2014 |
| Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking M Oba, K Aoyagi, K Miyata, Y Matsumoto, K Itaka, N Nishiyama, ... Molecular pharmaceutics 5 (6), 1080-1092, 2008 | 158 | 2008 |
| Modulated protonation of side chain aminoethylene repeats in N-substituted polyaspartamides promotes mRNA transfection H Uchida, K Itaka, T Nomoto, T Ishii, T Suma, M Ikegami, K Miyata, M Oba, ... Journal of the American Chemical Society 136 (35), 12396-12405, 2014 | 142 | 2014 |
| Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors Z Ge, Q Chen, K Osada, X Liu, TA Tockary, S Uchida, A Dirisala, T Ishii, ... Biomaterials 35 (10), 3416-3426, 2014 | 135 | 2014 |
| In situ quantitative monitoring of polyplexes and polyplex micelles in the blood circulation using intravital real-time confocal laser scanning microscopy T Nomoto, Y Matsumoto, K Miyata, M Oba, S Fukushima, N Nishiyama, ... Journal of controlled release 151 (2), 104-109, 2011 | 132 | 2011 |
| Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system H Takemoto, A Ishii, K Miyata, M Nakanishi, M Oba, T Ishii, Y Yamasaki, ... Biomaterials 31 (31), 8097-8105, 2010 | 132 | 2010 |
| Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp (DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown HJ Kim, A Ishii, K Miyata, Y Lee, S Wu, M Oba, N Nishiyama, K Kataoka Journal of controlled release 145 (2), 141-148, 2010 | 130 | 2010 |
| Size-controlled long-circulating PICsome as a ruler to measure critical cut-off disposition size into normal and tumor tissues Y Anraku, A Kishimura, A Kobayashi, M Oba, K Kataoka Chemical communications 47 (21), 6054-6056, 2011 | 119 | 2011 |
| Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery M Oba, K Miyata, K Osada, RJ Christie, M Sanjoh, W Li, S Fukushima, ... Biomaterials 32 (2), 652-663, 2011 | 118 | 2011 |
| Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation D Akagi, M Oba, H Koyama, N Nishiyama, S Fukushima, T Miyata, ... Gene therapy 14 (13), 1029-1038, 2007 | 111 | 2007 |
| Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles Y Vachutinsky, M Oba, K Miyata, S Hiki, MR Kano, N Nishiyama, ... Journal of controlled release 149 (1), 51-57, 2011 | 101 | 2011 |
| siRNA-based therapy ameliorates glomerulonephritis H Shimizu, Y Hori, S Kaname, K Yamada, N Nishiyama, S Matsumoto, ... Journal of the American Society of Nephrology 21 (4), 622-633, 2010 | 98 | 2010 |
| Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies M Han, Y Bae, N Nishiyama, K Miyata, M Oba, K Kataoka Journal of Controlled Release 121 (1-2), 38-48, 2007 | 98 | 2007 |
