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Hijai R Shin
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AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy
HJR Shin, H Kim, S Oh, JG Lee, M Kee, HJ Ko, MN Kweon, KJ Won, ...
Nature 534 (7608), 553-557, 2016
3832016
ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C
CY Lim, OB Davis, HR Shin, J Zhang, CA Berdan, X Jiang, JL Counihan, ...
Nature cell biology 21 (10), 1206-1218, 2019
2262019
Negative regulation of hypoxic responses via induced Reptin methylation
JS Lee, Y Kim, IS Kim, B Kim, HJ Choi, JM Lee, HJR Shin, JH Kim, JY Kim, ...
Molecular cell 39 (1), 71-85, 2010
1932010
Hypoxia-induced methylation of a pontin chromatin remodeling factor
JS Lee, Y Kim, J Bhin, HJR Shin, HJ Nam, SH Lee, JB Yoon, O Binda, ...
Proceedings of the National Academy of Sciences 108 (33), 13510-13515, 2011
1332011
Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition
CYS Chung, HR Shin, CA Berdan, B Ford, CC Ward, JA Olzmann, ...
Nature chemical biology 15 (8), 776-785, 2019
1322019
NPC1-mTORC1 signaling couples cholesterol sensing to organelle homeostasis and is a targetable pathway in Niemann-Pick type C
OB Davis, HR Shin, CY Lim, EY Wu, M Kukurugya, CF Maher, RM Perera, ...
Developmental cell 56 (3), 260-276. e7, 2021
1152021
The lysosome at the intersection of cellular growth and destruction
HR Shin, R Zoncu
Developmental cell 54 (2), 226-238, 2020
842020
PKCα-LSD1-NF-κB-signaling cascade is crucial for epigenetic control of the inflammatory response
D Kim, HJ Nam, W Lee, HY Yim, JY Ahn, SW Park, HJR Shin, R Yu, ...
Molecular cell 69 (3), 398-411. e6, 2018
792018
Epigenetic and transcriptional regulation of autophagy
HJR Shin, H Kim, KI Kim, SH Baek
Autophagy 12 (11), 2248-2249, 2016
542016
Bcl3-dependent stabilization of CtBP1 is crucial for the inhibition of apoptosis and tumor progression in breast cancer
HJ Choi, JM Lee, H Kim, HJ Nam, HJR Shin, D Kim, E Ko, DY Noh, KI Kim, ...
Biochemical and biophysical research communications 400 (3), 396-402, 2010
532010
Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth
S Gupta, J Yano, V Mercier, HH Htwe, HR Shin, G Rademaker, Z Cakir, ...
Nature cell biology 23 (3), 232-242, 2021
442021
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
HR Shin, YR Citron, L Wang, L Tribouillard, CS Goul, R Stipp, ...
Science 377 (6612), 1290-1298, 2022
372022
Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy
YS Yu, HR Shin, D Kim, SA Baek, SA Choi, H Ahn, A Shamim, J Kim, ...
Nature communications 11 (1), 6297, 2020
362020
Pontin functions as an essential coactivator for Oct4-dependent lincRNA expression in mouse embryonic stem cells
K Boo, J Bhin, Y Jeon, J Kim, HJR Shin, JE Park, K Kim, CR Kim, H Jang, ...
Nature communications 6 (1), 6810, 2015
282015
Nat. Photonics 11, 708 (2017)
HS Kang, CK Min, H Heo, C Kim, H Yang, G Kim, I Nam, SY Baek, ...
12
Finding sugar in the pantry: how galectins detect and signal lysosomal damage
HR Shin, R Zoncu
Molecular cell 70 (1), 5-7, 2018
32018
The hypothalamic–pituitary–gonadal axis controls muscle stem cell senescence through autophagosome clearance
JH Kim, I Park, HR Shin, J Rhee, JY Seo, YW Jo, K Yoo, SH Hann, ...
Journal of cachexia, sarcopenia and muscle 12 (1), 177-191, 2021
22021
mTORC1 modulators
DK Nomura, R Zoncu, AM Roberts, KF Cho, YSC Chung, H Shin, B Croze
US Patent 10,807,951, 2020
2020
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Articles 1–18