Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection NS Butler, J Moebius, LL Pewe, B Traore, OK Doumbo, LT Tygrett, ... Nature immunology 13 (2), 188-195, 2012 | 562 | 2012 |
Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-α secretion through IKK regulation of NF-κB S Sanlioglu, CM Williams, L Samavati, NS Butler, G Wang, PB McCray, ... Journal of Biological Chemistry 276 (32), 30188-30198, 2001 | 496 | 2001 |
Respiratory syncytial virus up-regulates TLR4 and sensitizes airway epithelial cells to endotoxin MM Monick, TO Yarovinsky, LS Powers, NS Butler, AB Carter, ... Journal of Biological Chemistry 278 (52), 53035-53044, 2003 | 380 | 2003 |
Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion J Illingworth, NS Butler, S Roetynck, J Mwacharo, SK Pierce, P Bejon, ... The Journal of Immunology 190 (3), 1038-1047, 2013 | 313 | 2013 |
Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria NW Schmidt, RL Podyminogin, NS Butler, VP Badovinac, BJ Tucker, ... Proceedings of the National Academy of Sciences 105 (37), 14017-14022, 2008 | 301 | 2008 |
Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites NS Butler, NW Schmidt, AM Vaughan, AS Aly, SHI Kappe, JT Harty Cell host & microbe 9 (6), 451-462, 2011 | 266 | 2011 |
Interleukin-10 directly inhibits CD8+ T cell function by enhancing N-glycan branching to decrease antigen sensitivity LK Smith, GM Boukhaled, SA Condotta, S Mazouz, JJ Guthmiller, R Vijay, ... Immunity 48 (2), 299-312. e5, 2018 | 229 | 2018 |
Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites NW Schmidt, NS Butler, VP Badovinac, JT Harty PLoS pathogens 6 (7), e1000998, 2010 | 218 | 2010 |
T cell-mediated immunity to malaria SP Kurup, NS Butler, JT Harty Nature Reviews Immunology 19 (7), 457-471, 2019 | 202 | 2019 |
Role of repeated lung injury and genetic background in bleomycin-induced fibrosis MP Chung, MM Monick, NY Hamzeh, NS Butler, LS Powers, ... American journal of respiratory cell and molecular biology 29 (3), 375-380, 2003 | 165 | 2003 |
Anti-inflammatory response is associated with mortality and severity of infection in sepsis A Ashare, LS Powers, NS Butler, KC Doerschug, MM Monick, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 288 (4 …, 2005 | 142 | 2005 |
Regulatory T cells impede acute and long-term immunity to blood-stage malaria through CTLA-4 SP Kurup, N Obeng-Adjei, SM Anthony, B Traore, OK Doumbo, NS Butler, ... Nature medicine 23 (10), 1220-1225, 2017 | 119 | 2017 |
Phosphatidylinositol 3-kinase activity negatively regulates stability of cyclooxygenase 2 mRNA MM Monick, PK Robeff, NS Butler, DM Flaherty, AB Carter, MW Peterson, ... Journal of Biological Chemistry 277 (36), 32992-33000, 2002 | 109 | 2002 |
PD-1 co-inhibitory and OX40 co-stimulatory crosstalk regulates helper T cell differentiation and anti-Plasmodium humoral immunity RA Zander, N Obeng-Adjei, JJ Guthmiller, DI Kulu, J Li, A Ongoiba, ... Cell host & microbe 17 (5), 628-641, 2015 | 107 | 2015 |
Differential effector pathways regulate memory CD8 T cell immunity against Plasmodium berghei versus P. yoelii sporozoites NS Butler, NW Schmidt, JT Harty The Journal of Immunology 184 (5), 2528-2538, 2010 | 101 | 2010 |
Immunologic considerations for generating memory CD8 T cells through vaccination NS Butler, JC Nolz, JT Harty Cellular microbiology 13 (7), 925-933, 2011 | 95 | 2011 |
Sphingosine kinase mediates activation of extracellular signal–related kinase and Akt by respiratory syncytial virus MM Monick, K Cameron, LS Powers, NS Butler, D McCoy, RK Mallampalli, ... American journal of respiratory cell and molecular biology 30 (6), 844-852, 2004 | 92 | 2004 |
Altered IL-4 mRNA stability correlates with Th1 and Th2 bias and susceptibility to hypersensitivity pneumonitis in two inbred strains of mice NS Butler, MM Monick, TO Yarovinsky, LS Powers, GW Hunninghake The Journal of Immunology 169 (7), 3700-3709, 2002 | 91 | 2002 |
Cutting edge: IL-10 is essential for the generation of germinal center B cell responses and anti-plasmodium humoral immunity JJ Guthmiller, AC Graham, RA Zander, RL Pope, NS Butler The Journal of Immunology 198 (2), 617-622, 2017 | 87 | 2017 |
Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated N Butler, L Pewe, K Trandem, S Perlman Virology 347 (2), 410-421, 2006 | 85 | 2006 |