Single-cell RNA-seq reveals the transcriptional landscape and heterogeneity of aortic macrophages in murine atherosclerosis C Cochain, E Vafadarnejad, P Arampatzi, J Pelisek, H Winkels, K Ley, ... Circulation research 122 (12), 1661-1674, 2018 | 684 | 2018 |
Atlas of the immune cell repertoire in mouse atherosclerosis defined by single-cell RNA-sequencing and mass cytometry H Winkels, E Ehinger, M Vassallo, K Buscher, HQ Dinh, K Kobiyama, ... Circulation research 122 (12), 1675-1688, 2018 | 442 | 2018 |
T cell subsets and functions in atherosclerosis R Saigusa, H Winkels, K Ley Nature Reviews Cardiology 17 (7), 387-401, 2020 | 396 | 2020 |
Meta-analysis of leukocyte diversity in atherosclerotic mouse aortas A Zernecke, H Winkels, C Cochain, JW Williams, D Wolf, O Soehnlein, ... Circulation research 127 (3), 402-426, 2020 | 239 | 2020 |
Regulatory CD4+ T Cells Recognize Major Histocompatibility Complex Class II Molecule–Restricted Peptide Epitopes of Apolipoprotein B T Kimura, K Kobiyama, H Winkels, K Tse, J Miller, M Vassallo, D Wolf, ... Circulation 138 (11), 1130-1143, 2018 | 141 | 2018 |
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance A Chatzigeorgiou, T Seijkens, B Zarzycka, D Engel, M Poggi, ... Proceedings of the National Academy of Sciences 111 (7), 2686-2691, 2014 | 140 | 2014 |
Platelet CD40 exacerbates atherosclerosis by transcellular activation of endothelial cells and leukocytes N Gerdes, T Seijkens, D Lievens, MJE Kuijpers, H Winkels, D Projahn, ... Arteriosclerosis, thrombosis, and vascular biology 36 (3), 482-490, 2016 | 122 | 2016 |
Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100–Reactive CD4+ T-Regulatory Cells D Wolf, T Gerhardt, H Winkels, NA Michel, AB Pramod, Y Ghosheh, ... Circulation 142 (13), 1279-1293, 2020 | 119 | 2020 |
Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential C Spitz, H Winkels, C Bürger, C Weber, E Lutgens, GK Hansson, ... Cellular and molecular life sciences 73, 901-922, 2016 | 118 | 2016 |
Single cell RNA sequencing in atherosclerosis research JW Williams, H Winkels, CP Durant, K Zaitsev, Y Ghosheh, K Ley Circulation research 126 (9), 1112-1126, 2020 | 108 | 2020 |
A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense D Wolf, N Anto-Michel, H Blankenbach, A Wiedemann, K Buscher, ... Nature communications 9 (1), 525, 2018 | 95 | 2018 |
Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production M Orecchioni, K Kobiyama, H Winkels, Y Ghosheh, S McArdle, Z Mikulski, ... Science 375 (6577), 214-221, 2022 | 94 | 2022 |
Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis D Lievens, KL Habets, AK Robertson, Y Laouar, H Winkels, ... European heart journal 34 (48), 3717-3727, 2013 | 78 | 2013 |
IL-1 family cytokines in cardiovascular disease S Pfeiler, H Winkels, M Kelm, N Gerdes Cytokine 122, 154215, 2019 | 69 | 2019 |
Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain JM Navia-Pelaez, SH Choi, L dos Santos Aggum Capettini, Y Xia, ... Journal of Experimental Medicine 218 (7), e20202059, 2021 | 60 | 2021 |
PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function M Bianchini, J Duchêne, D Santovito, MJ Schloss, M Evrard, H Winkels, ... Science immunology 4 (36), eaar3054, 2019 | 59 | 2019 |
Migratory and dancing macrophage subsets in atherosclerotic lesions S McArdle, K Buscher, Y Ghosheh, AB Pramod, J Miller, H Winkels, ... Circulation research 125 (12), 1038-1051, 2019 | 58 | 2019 |
Heterogeneity of T cells in atherosclerosis defined by single-cell RNA-sequencing and cytometry by time of flight H Winkels, D Wolf Arteriosclerosis, thrombosis, and vascular biology 41 (2), 549-563, 2021 | 54 | 2021 |
Atherosclerosis in the single-cell era H Winkels, E Ehinger, Y Ghosheh, D Wolf, K Ley Current opinion in lipidology 29 (5), 389-396, 2018 | 48 | 2018 |
The enzymatic and non-enzymatic function of myeloperoxidase (MPO) in inflammatory communication Y Kargapolova, S Geißen, R Zheng, S Baldus, H Winkels, M Adam Antioxidants 10 (4), 562, 2021 | 47 | 2021 |