| Tandem Diels− Alder cycloadditions in organic synthesis JD Winkler Chemical reviews 96 (1), 167-176, 1996 | 452 | 1996 |
| Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma XH Ma, SF Piao, S Dey, Q Mcafee, G Karakousis, J Villanueva, LS Hart, ... The Journal of clinical investigation 124 (3), 1406-1417, 2014 | 449 | 2014 |
| Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency Q McAfee, Z Zhang, A Samanta, SM Levi, XH Ma, S Piao, JP Lynch, ... Proceedings of the National Academy of Sciences 109 (21), 8253-8258, 2012 | 407 | 2012 |
| SIRT1 is downregulated by autophagy in senescence and ageing C Xu, L Wang, P Fozouni, G Evjen, V Chandra, J Jiang, C Lu, M Nicastri, ... Nature cell biology 22 (10), 1170-1179, 2020 | 350 | 2020 |
| Reduction of clofazimine by mycobacterial type 2 NADH: quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species T Yano, S Kassovska-Bratinova, JS Teh, J Winkler, K Sullivan, A Isaacs, ... Journal of Biological Chemistry 286 (12), 10276-10287, 2011 | 347 | 2011 |
| De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers S Choi, A Isaacs, D Clements, D Liu, H Kim, RW Scott, JD Winkler, ... Proceedings of the National Academy of Sciences 106 (17), 6968-6973, 2009 | 346 | 2009 |
| Nontoxic membrane‐active antimicrobial arylamide oligomers D Liu, S Choi, B Chen, RJ Doerksen, DJ Clements, JD Winkler, ML Klein, ... Angewandte Chemie International Edition 43 (9), 1158-1162, 2004 | 288 | 2004 |
| Photodynamic fluorescent metal ion sensors with parts per billion sensitivity JD Winkler, CM Bowen, V Michelet Journal of the American Chemical Society 120 (13), 3237-3242, 1998 | 271 | 1998 |
| CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers S Vijayaraghavan, C Karakas, I Doostan, X Chen, T Bui, M Yi, ... Nature communications 8 (1), 15916, 2017 | 261 | 2017 |
| [2+ 2] Photocycloaddition/fragmentation strategies for the synthesis of natural and unnatural products JD Winkler, CM Bowen, F Liotta Chemical reviews 95 (6), 2003-2020, 1995 | 249 | 1995 |
| The first total synthesis of (±)-ingenol JD Winkler, MB Rouse, MF Greaney, SJ Harrison, YT Jeon Journal of the American Chemical Society 124 (33), 9726-9728, 2002 | 219 | 2002 |
| Nebulized sildenafil is a selective pulmonary vasodilator in lambs with acute pulmonary hypertension F Ichinose, J Erana-Garcia, J Hromi, Y Raveh, R Jones, L Krim, ... Critical care medicine 29 (5), 1000-1005, 2001 | 209 | 2001 |
| The first total syntheses of ircinol A, ircinal A, and manzamines A and D JD Winkler, JM Axten Journal of the American Chemical Society 120 (25), 6425, 1998 | 191 | 1998 |
| PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer VW Rebecca, MC Nicastri, C Fennelly, CI Chude, JS Barber-Rotenberg, ... Cancer discovery 9 (2), 220-229, 2019 | 187 | 2019 |
| A unified approach to targeting the lysosome's degradative and growth signaling roles VW Rebecca, MC Nicastri, N McLaughlin, C Fennelly, Q McAfee, ... Cancer discovery 7 (11), 1266-1283, 2017 | 163 | 2017 |
| Mimics of transaminase enzymes R Breslow, AW Czarnik, M Lauer, R Leppkes, J Winkler, S Zimmerman Journal of the American Chemical Society 108 (8), 1969-1979, 1986 | 159 | 1986 |
| Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors CA Natale, EK Duperret, J Zhang, R Sadeghi, A Dahal, KT O'Brien, ... Elife 5, e15104, 2016 | 123 | 2016 |
| A model for the taxol (paclitaxel)/epothilone pharmacophore JD Winkler, PH Axelsen Bioorganic & Medicinal Chemistry Letters 6 (24), 2963-2966, 1996 | 121 | 1996 |
| Targeting quiescent leukemic stem cells using second generation autophagy inhibitors P Baquero, A Dawson, A Mukhopadhyay, EM Kuntz, R Mitchell, ... Leukemia 33 (4), 981-994, 2019 | 118 | 2019 |
| Development of Potent and Selective Inhibitors of Aldo–Keto Reductase 1C3 (Type 5 17β-Hydroxysteroid Dehydrogenase) Based on N-Phenyl-Aminobenzoates … AO Adeniji, BM Twenter, MC Byrns, Y Jin, M Chen, JD Winkler, ... Journal of medicinal chemistry 55 (5), 2311-2323, 2012 | 116 | 2012 |
