| Inflammasomes: mechanism of action, role in disease, and therapeutics H Guo, JB Callaway, JPY Ting Nature medicine 21 (7), 677-687, 2015 | 3120 | 2015 |
| Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol SY Liu, R Aliyari, K Chikere, G Li, MD Marsden, JK Smith, O Pernet, ... Immunity 38 (1), 92-105, 2013 | 638 | 2013 |
| NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes L Freeman, H Guo, CN David, WJ Brickey, S Jha, JPY Ting Journal of Experimental Medicine 214 (5), 1351-1370, 2017 | 325 | 2017 |
| HIV-1 infection induces interleukin-1β production via TLR8 protein-dependent and NLRP3 inflammasome mechanisms in human monocytes H Guo, J Gao, DJ Taxman, JPY Ting, L Su Journal of Biological Chemistry 289 (31), 21716-21726, 2014 | 176 | 2014 |
| NLRX1 sequesters STING to negatively regulate the interferon response, thereby facilitating the replication of HIV-1 and DNA viruses H Guo, R König, M Deng, M Riess, J Mo, L Zhang, A Petrucelli, SM Yoh, ... Cell host & microbe 19 (4), 515-528, 2016 | 158 | 2016 |
| Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice G Li, M Cheng, J Nunoya, L Cheng, H Guo, H Yu, Y Liu, L Su, L Zhang PLoS pathogens 10 (7), e1004291, 2014 | 112 | 2014 |
| Role of tegument proteins in herpesvirus assembly and egress H Guo, S Shen, L Wang, H Deng Protein & cell 1 (11), 987-998, 2010 | 107 | 2010 |
| Vpr targets TET2 for degradation by CRL4VprBP E3 ligase to sustain IL-6 expression and enhance HIV-1 replication L Lv, Q Wang, Y Xu, LC Tsao, T Nakagawa, H Guo, L Su, Y Xiong Molecular cell 70 (5), 961-970. e5, 2018 | 92 | 2018 |
| NLRP12 regulates anti-viral RIG-I activation via interaction with TRIM25 ST Chen, L Chen, DSC Lin, SY Chen, YP Tsao, H Guo, FJ Li, WT Tseng, ... Cell host & microbe 25 (4), 602-616. e7, 2019 | 81 | 2019 |
| NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR H Feng, EM Lenarcic, D Yamane, E Wauthier, J Mo, H Guo, DR McGivern, ... Nature immunology 18 (12), 1299-1309, 2017 | 77 | 2017 |
| Open reading frame 33 of a gammaherpesvirus encodes a tegument protein essential for virion morphogenesis and egress H Guo, L Wang, L Peng, ZH Zhou, H Deng Journal of virology 83 (20), 10582-10595, 2009 | 70 | 2009 |
| Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication H Guo, QI Wang, K Ghneim, LI Wang, E Rampanelli, E Holley-Guthrie, ... Nature immunology 22 (4), 423-433, 2021 | 69 | 2021 |
| The innate immune sensor NLRC3 acts as a rheostat that fine-tunes T cell responses in infection and autoimmunity T Uchimura, Y Oyama, M Deng, H Guo, JE Wilson, E Rampanelli, ... Immunity 49 (6), 1049-1061. e6, 2018 | 64 | 2018 |
| Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR M Deng, H Guo, JW Tam, BM Johnson, WJ Brickey, JS New, A Lenox, ... Journal of Experimental Medicine 216 (12), 2838-2853, 2019 | 43 | 2019 |
| NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency Z Ma, SE Hopcraft, F Yang, A Petrucelli, H Guo, JPY Ting, DP Dittmer, ... PLoS pathogens 13 (5), e1006350, 2017 | 41 | 2017 |
| TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination M Deng, JW Tam, L Wang, K Liang, S Li, L Zhang, H Guo, X Luo, Y Zhang, ... Nature communications 11 (1), 2193, 2020 | 37 | 2020 |
| Distinct domains in ORF52 tegument protein mediate essential functions in murine gammaherpesvirus 68 virion tegumentation and secondary envelopment L Wang, H Guo, N Reyes, S Lee, E Bortz, F Guo, R Sun, L Tong, H Deng Journal of virology 86 (3), 1348-1357, 2012 | 27 | 2012 |
| An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2 KC Barnett, Y Xie, T Asakura, D Song, K Liang, SA Taft-Benz, H Guo, ... Cell Host & Microbe 31 (2), 243-259. e6, 2023 | 24 | 2023 |
| CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo LC Tsao, H Guo, J Jeffrey, JA Hoxie, L Su Retrovirology 13, 1-13, 2016 | 21 | 2016 |
| Gammaherpesvirus tegument protein ORF33 is associated with intranuclear capsids at an early stage of the tegumentation process S Shen, X Jia, H Guo, H Deng Journal of virology 89 (10), 5288-5297, 2015 | 20 | 2015 |
