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Daniel J Tyrrell, PhD
Daniel J Tyrrell, PhD
Assistant Professor - Pathology, Molecular and Cellular, UAB
Verified email at uabmc.edu - Homepage
Title
Cited by
Cited by
Year
Ageing and atherosclerosis: vascular intrinsic and extrinsic factors and potential role of IL-6
DJ Tyrrell, DR Goldstein
Nature Reviews Cardiology 18 (1), 58-68, 2021
2912021
Age-associated mitochondrial dysfunction accelerates atherogenesis
DJ Tyrrell, MG Blin, J Song, SC Wood, M Zhang, DA Beard, DR Goldstein
Circulation research 126 (3), 298-314, 2020
1512020
Pathophysiology of heart failure and frailty: a common inflammatory origin?
L Bellumkonda, D Tyrrell, SL Hummel, DR Goldstein
Aging cell 16 (3), 444-450, 2017
1072017
Respirometric profiling of muscle mitochondria and blood cells are associated with differences in gait speed among community-dwelling older adults
DJ Tyrrell, MS Bharadwaj, CG Van Horn, SB Kritchevsky, BJ Nicklas, ...
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2015
1002015
Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial health
DJ Tyrrell, MS Bharadwaj, MJ Jorgensen, TC Register, AJA Molina
Redox biology 10, 65-77, 2016
942016
Blood-cell bioenergetics are associated with physical function and inflammation in overweight/obese older adults
DJ Tyrrell, MS Bharadwaj, CG Van Horn, AP Marsh, BJ Nicklas, ...
Experimental gerontology 70, 84-91, 2015
772015
Blood‐based bioenergetic profiling reflects differences in brain bioenergetics and metabolism
DJ Tyrrell, MS Bharadwaj, MJ Jorgensen, TC Register, C Shively, ...
Oxidative Medicine and Cellular Longevity 2017 (1), 7317251, 2017
612017
Relationships between mitochondrial content and bioenergetics with obesity, body composition and fat distribution in healthy older adults
MS Bharadwaj, DJ Tyrrell, I Leng, JL Demons, MF Lyles, JJ Carr, ...
BMC obesity 2, 1-11, 2015
372015
Preparation and respirometric assessment of mitochondria isolated from skeletal muscle tissue obtained by percutaneous needle biopsy
MS Bharadwaj, DJ Tyrrell, MF Lyles, JL Demons, GW Rogers, AJA Molina
JoVE (Journal of Visualized Experiments), e52350, 2015
362015
Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis
G Hindy, DJ Tyrrell, A Vasbinder, C Wei, F Presswalla, H Wang, P Blakely, ...
The Journal of clinical investigation 132 (24), 2022
342022
Aging impairs mitochondrial function and mitophagy and elevates interleukin 6 within the cerebral vasculature
DJ Tyrrell, MG Blin, J Song, SC Wood, DR Goldstein
Journal of the American Heart Association 9 (23), e017820, 2020
282020
Macrophage migration inhibitory factor enhances influenza-associated mortality in mice
CA Smith, DJ Tyrell, UA Kulkarni, S Wood, L Leng, RL Zemans, R Bucala, ...
JCI insight 4 (13), 2019
182019
Aging alters the aortic proteome in health and thoracic aortic aneurysm
DJ Tyrrell, J Chen, BY Li, SC Wood, W Rosebury-Smith, HA Remmer, ...
Arteriosclerosis, thrombosis, and vascular biology 42 (8), 1060-1076, 2022
132022
Age‐associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis
J Song, D Farris, P Ariza, S Moorjani, M Varghese, M Blin, J Chen, ...
Aging Cell 22 (2), e13783, 2023
112023
Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice
J Song, Y Zhang, RA Frieler, A Andren, S Wood, DJ Tyrrell, ...
The Journal of clinical investigation 134 (3), 2024
82024
Cardiovascular aging: spotlight on mitochondria
MA Ali, R Gioscia-Ryan, D Yang, NR Sutton, DJ Tyrrell
American Journal of Physiology-Heart and Circulatory Physiology 326 (2 …, 2024
52024
Clonally expanded memory CD8+ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice
DJ Tyrrell, KM Wragg, J Chen, H Wang, J Song, MG Blin, C Bolding, ...
Nature Aging 3 (12), 1576-1590, 2023
52023
Mitochondrial respiratory states and rates: Building blocks of mitochondrial physiology (Part 1)
E Gnaiger, B Ahn, MG Alves, F Amati, C Aral, O Arandarčikaitė, ...
32018
Aging Enhances Vascular Mitochondrial Dysfunction Prior to Hyperlipidemia to Accelerate Atherosclerosis
D Tyrrell, DR Goldstein
Circulation 140 (Suppl_1), A12990-A12990, 2019
22019
Analysis of NIH K99/R00 awards and the career progression of awardees
NC Woitowich, SR Hengel, C Solis, TP Vilgalys, J Babdor, DJ Tyrrell
Elife 12, RP88984, 2024
12024
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