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Bieneke Janssen
Bieneke Janssen
Radboudumc
Verified email at radboudumc.nl
Title
Cited by
Cited by
Year
PET imaging of microglial activation—beyond targeting TSPO
B Janssen, DJ Vugts, AD Windhorst, RH Mach
Molecules 23 (3), 607, 2018
1152018
Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis
W Beaino, B Janssen, G Kooij, SMA van der Pol, B van Het Hof, ...
Journal of neuroinflammation 14, 1-16, 2017
1082017
Imaging of neuroinflammation in Alzheimer's disease, multiple sclerosis and stroke: Recent developments in positron emission tomography
B Janssen, DJ Vugts, U Funke, GT Molenaar, PS Kruijer, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (3), 425-441, 2016
812016
Synthesis and initial preclinical evaluation of the P2X7 receptor antagonist [11C] A‐740003 as a novel tracer of neuroinflammation
B Janssen, DJ Vugts, U Funke, A Spaans, RC Schuit, E Kooijman, ...
Journal of Labelled Compounds and Radiopharmaceuticals 57 (8), 509-516, 2014
802014
Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation
B Janssen, DJ Vugts, SM Wilkinson, D Ory, S Chalon, JJM Hoozemans, ...
Scientific reports 8 (1), 6580, 2018
642018
The P2X7 receptor tracer [11C]SMW139 as an in vivo marker of neuroinflammation in multiple sclerosis: a first-in man study
MHJ Hagens, SSV Golla, B Janssen, DJ Vugts, W Beaino, AD Windhorst, ...
European journal of nuclear medicine and molecular imaging 47, 379-389, 2020
542020
Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state
A Villa, B Klein, B Janssen, J Pedragosa, G Pepe, B Zinnhardt, DJ Vugts, ...
Theranostics 8 (19), 5400, 2018
492018
Pharmacological Evaluation of Novel Bioisosteres of an Adamantanyl Benzamide P2X7 Receptor Antagonist
SM Wilkinson, ML Barron, J O’Brien-Brown, B Janssen, L Stokes, ...
ACS chemical neuroscience 8 (11), 2374-2380, 2017
422017
Development of brain PET imaging agents: Strategies for imaging neuroinflammation in Alzheimer's disease
B Janssen, RH Mach
Progress in molecular biology and translational science 165, 371-399, 2019
382019
Synthesis and characterization of high affinity fluorogenic α-synuclein probes
Z Lengyel-Zhand, JJ Ferrie, B Janssen, CJ Hsieh, T Graham, K Xu, ...
Chemical communications 56 (24), 3567-3570, 2020
332020
Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening
JJ Ferrie, Z Lengyel-Zhand, B Janssen, MG Lougee, S Giannakoulias, ...
Chemical Science 11 (47), 12746-12754, 2020
322020
Towards PET imaging of the dynamic phenotypes of microglia
W Beaino, B Janssen, DJ Vugts, HE de Vries, AD Windhorst
Clinical & Experimental Immunology 206 (3), 282-300, 2021
292021
11C‐labeled and 18F‐labeled PET ligands for subtype‐specific imaging of histamine receptors in the brain
U Funke, DJ Vugts, B Janssen, A Spaans, PS Kruijer, AA Lammertsma, ...
Journal of Labelled Compounds and Radiopharmaceuticals 56 (3-4), 120-129, 2013
252013
PET imaging of P2X7R in the experimental autoimmune encephalomyelitis model of multiple sclerosis using [11C]SMW139
W Beaino, B Janssen, E Kooijman, R Vos, RC Schuit, J O’Brien-Brown, ...
Journal of neuroinflammation 17, 1-18, 2020
182020
Novel Thienopyrimidine-Based PET Tracers for P2Y12 Receptor Imaging in the Brain
B van der Wildt, B Janssen, A Pekošak, EJL Stéen, RC Schuit, ...
ACS Chemical Neuroscience 12 (23), 4465-4474, 2021
152021
Initial evaluation of P2X (7) R antagonists [C-11] A-740003 and [C-11] SMW64-D16 as PET tracers of microglial activation in neuroinflammation
B Janssen, D Ory, SM Wilkinson, DJ Vugts, EJ Kooijman, J Verbeek, ...
Journal Of Labelled Compounds & Radiopharmaceuticals 58, S277-S277, 2015
52015
PET imaging of purinergic receptors
B Janssen, DJ Vugts, AD Windhorst
PET and SPECT of Neurobiological Systems, 879-889, 2021
42021
Synthesis of the first carbon-11 labelled P2Y (12) receptor antagonist for PET imaging of microglial activation in neuroinflammation
B Janssen, DJ Vugts, U Funke, GT Molenaar, PS Kruijer, F Dolle, ...
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 58, S44-S44, 2015
32015
Imaging histamine receptors using PET and SPECT
U Funke, DJ Vugts, B Janssen, A Spaans, PS Kruijer, AA Lammertsma, ...
PET and SPECT of Neurobiological Systems, 331-376, 2014
32014
Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search
B Janssen, G Tian, Z Lengyel-Zhand, CJ Hsieh, MG Lougee, A Riad, K Xu, ...
Molecular Imaging and Biology 25 (4), 704-719, 2023
22023
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