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Timothy Tan
Timothy Tan
Center for Biophysics and Quantitative Biology, University of Illinois Urbana-Champaign
Verified email at illinois.edu
Title
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Cited by
Year
An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants
KK Chan, TJC Tan, KK Narayanan, E Procko
Science Advances 7 (8), eabf1738, 2021
1302021
Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain
TJC Tan, M Yuan, K Kuzelka, GC Padron, JR Beal, X Chen, Y Wang, ...
Nature Communications 12, 1-10, 2021
492021
Probing the biophysical constraints of SARS-CoV-2 spike N-terminal domain using deep mutational scanning
WO Ouyang, TJC Tan, R Lei, G Song, C Kieffer, R Andrabi, KA Matreyek, ...
Science Advances 8 (47), eadd7221, 2022
172022
High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike
TJC Tan, Z Mou, R Lei, WO Ouyang, M Yuan, G Song, R Andrabi, ...
Nature Communications 14, 2003, 2023
162023
Molecular analysis of a public cross-neutralizing antibody response to SARS-CoV-2
M Yuan, Y Wang, H Lv, TJC Tan, IA Wilson, NC Wu
Cell Reports 41 (7), 2022
142022
The evolutionary potential of influenza A virus hemagglutinin is highly constrained by epistatic interactions with neuraminidase
T Liu, Y Wang, TJC Tan, NC Wu, CB Brooke
Cell Host & Microbe 30 (10), 1363-1369. e4, 2022
122022
Virus-induced activation of the rac1 protein at the site of respiratory syncytial virus assembly is a requirement for virus particle assembly on infected cells
LI Ravi, TJ Tan, BH Tan, RJ Sugrue
Virology 557, 86-99, 2021
112021
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH
T Schulte, MD Panas, X Han, L Williams, N Kedersha, JS Fleck, TJC Tan, ...
Open Biology 13 (5), 220369, 2023
8*2023
Mutational fitness landscape of human influenza H3N2 neuraminidase
R Lei, AH Garcia, TJC Tan, QW Teo, Y Wang, X Zhang, S Luo, SK Nair, ...
Cell reports 42 (1), 2023
82023
Egg-adaptive mutations of human influenza H3N2 virus are contingent on natural evolution
W Liang, TJC Tan, Y Wang, H Lv, Y Sun, R Bruzzone, CKP Mok, NC Wu
PLoS pathogens 18 (9), e1010875, 2022
82022
Arabidopsis thaliana G3BP Ortholog Rescues Mammalian Stress Granule Phenotype across Kingdoms
H Reuper, B Götte, L Williams, TJC Tan, GM McInerney, MD Panas, ...
International Journal of Molecular Sciences 22 (12), 6287, 2021
62021
Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase
R Lei, W Kim, H Lv, Z Mou, MJ Scherm, AJ Schmitz, JS Turner, TJC Tan, ...
Immunity 56 (11), 2621-2634. e6, 2023
42023
Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase
R Lei, TJC Tan, A Hernandez Garcia, Y Wang, M Diefenbacher, C Teo, ...
Nature communications 13, 6443, 2022
42022
Interactions between Influenza A Virus Nucleoprotein and Gene Segment Untranslated Regions Facilitate Selective Modulation of Viral Gene Expression
M Diefenbacher, TJC Tan, DLV Bauer, BM Stadtmueller, NC Wu, ...
Journal of Virology, e00205-22, 2022
32022
An explainable language model for antibody specificity prediction using curated influenza hemagglutinin antibodies
Y Wang, H Lv, R Lei, YH Yeung, IR Shen, D Choi, QW Teo, TJC Tan, ...
bioRxiv, 2023
22023
Widespread impact of immunoglobulin V gene allelic polymorphisms on antibody reactivity
M Yuan, Z Feng, H Lv, N So, IR Shen, TJC Tan, QW Teo, WO Ouyang, ...
bioRxiv, 2023.06. 06.543969, 2023
12023
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike
TJC Tan, AK Verma, A Odle, R Lei, DK Meyerholz, KA Matreyek, ...
Proceedings of the National Academy of Sciences 121 (15), e2317222121, 2024
2024
Natural variation in neuraminidase activity influences the evolutionary potential of the seasonal H1N1 lineage hemagglutinin
T Liu, WK Reiser, TJC Tan, H Lv, J Rivera-Cardona, K Heimburger, ...
bioRxiv, 2024.03. 18.585603, 2024
2024
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning
R Lei, E Qing, A Odle, M Yuan, TJC Tan, N So, WO Ouyang, IA Wilson, ...
Biorxiv, 2023
2023
Stringent and complex sequence constraints of an IGHV1-69 broadly neutralizing antibody to influenza HA stem
QW Teo, Y Wang, H LYU, TJC Tan, R Lei, KJ Mao, NC Wu
bioRxiv, 2023.07. 06.547908, 2023
2023
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