Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia XJ Yan, J Xu, ZH Gu, CM Pan, G Lu, Y Shen, JY Shi, YM Zhu, L Tang, ... Nature genetics 43 (4), 309-315, 2011 | 980 | 2011 |
Arsenic trioxide controls the fate of the PML-RARα oncoprotein by directly binding PML XW Zhang, XJ Yan, ZR Zhou, FF Yang, ZY Wu, HB Sun, WX Liang, ... Science 328 (5975), 240-243, 2010 | 842 | 2010 |
From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemia SJ Chen, GB Zhou, XW Zhang, JH Mao, Z Chen Blood 117 (24), 6425-6437, 2011 | 228 | 2011 |
Truncated ERG Oncoproteins from TMPRSS2-ERG fusions are Resistant to SPOP-Mediated Proteasome degradation J An, S Ren, SJ Murphy, S Dalangood, C Chang, X Pang, Y Cui, L Wang, ... Molecular cell 59 (6), 904-916, 2015 | 153 | 2015 |
Prophylaxis against carcinogenesis in three kinds of unestablished tumor models via IL12-gene-engineered MSCs X Chen, R Wang, X Zhao, Y Wei, M Hu, Y Wang, X Zhang, R Zhang, ... Carcinogenesis 27 (12), 2434-2441, 2006 | 104 | 2006 |
Active immunotherapy of tumors with a recombinant xenogeneic endoglin as a model antigen GH Tan, YQ Wei, L Tian, X Zhao, L Yang, J Li, QM He, Y Wu, YJ Wen, T Yi, ... European journal of immunology 34 (7), 2012-2021, 2004 | 70 | 2004 |
A stress-induced response complex (SIRC) shuttles miRNAs, siRNAs, and oligonucleotides to the nucleus D Castanotto, X Zhang, J Alluin, X Zhang, J Rüger, B Armstrong, J Rossi, ... Proceedings of the National Academy of Sciences, 201721346, 2018 | 44 | 2018 |
Anti-angiogenesis therapy based on the bone marrow-derived stromal cells genetically engineered to express sFlt-1 in mouse tumor model M Hu, JL Yang, H Teng, YQ Jia, R Wang, XW Zhang, Y Wu, Y Luo, ... BMC cancer 8 (1), 306, 2008 | 38 | 2008 |
6BIO Enhances Oligonucleotide Activity in Cells: A Potential Combinatorial Anti-androgen Receptor Therapy in Prostate Cancer Cells X Zhang, D Castanotto, S Nam, D Horne, C Stein Molecular Therapy 25 (1), 79-91, 2017 | 28 | 2017 |
Aberrant transcriptional regulation of the MLL fusion partner EEN by AML1-ETO and its implication in leukemogenesis LH Ma, H Liu, H Xiong, B Chen, XW Zhang, YY Wang, HY Le, QH Huang, ... Blood 109 (2), 769-777, 2007 | 15 | 2007 |
Mannan-modified adenovirus as a vaccine to induce antitumor immunity ZY Ding, Y Wu, Y Luo, JM Su, Q Li, XW Zhang, JY Liu, QM He, L Yang, ... Gene therapy 14 (8), 657-663, 2007 | 14 | 2007 |
Systemic inhibition of tumor growth by soluble Flk-1 gene therapy combined with cisplatin R Wang, XW Zhang, GQ Wang, XC Chen, L Tian, HS Yang, M Hu, F Peng, ... Cancer gene therapy 13 (10), 940-947, 2006 | 13 | 2006 |
Ammonium and arsenic trioxide are potent facilitators of oligonucleotide function when delivered by gymnosis X Zhang, D Castanotto, X Liu, A Shemi, CA Stein Nucleic Acids Research, 2018 | 8 | 2018 |
Human T lymphocyte responses against lung cancer induced by recombinant truncated mouse EGFR B Hu, Y Wei, L Tian, X Zhao, Y Lu, Y Wu, B Yao, X Zhang Cancer Immunology, Immunotherapy 55 (4), 386-393, 2006 | 7 | 2006 |
A Multifunctional LNA Oligonucleotide-Based Strategy Blocks AR Expression and Transactivation Activity in PCa Cells D Castanotto, X Zhang, J Rüger, J Alluin, R Sharma, P Pirrotte, L Joenson, ... Molecular Therapy-Nucleic Acids 23, 63-75, 2021 | 5 | 2021 |
3D local structure around Zn in Kti11p as a representative Zn-(Cys) 4 motif as obtained by MXAN M Yu, F Yang, W Chu, Y Wang, H Zhao, B Gao, W Zhao, J Sun, F Wu, ... Biochemical and biophysical research communications 374 (1), 28-32, 2008 | 4 | 2008 |
Nanobiotechnological gene transfer vectors in gene therapy]. X Zhang, L Tian, Y Wei Sheng wu yi xue gong cheng xue za zhi= Journal of biomedical engineering …, 2005 | 1 | 2005 |
Oxidative mannan-conjugated LL/2c tumor cell vaccine induces potent Thl responses Z Xiaowei, T Ling, K Bing, D Zhenyu, W Yuquan West China Medical Journal 19 (2), 183-184, 2004 | | 2004 |