| Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex E Querido, P Blanchette, Q Yan, T Kamura, M Morrison, D Boivin, ... Genes & development 15 (23), 3104-3117, 2001 | 619 | 2001 |
| Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection J Wei, MM Alfajaro, PC DeWeirdt, RE Hanna, WJ Lu-Culligan, WL Cai, ... Cell 184 (1), 76-91. e13, 2021 | 507* | 2021 |
| The retinoblastoma binding protein RBP2 is an H3K4 demethylase RJ Klose, Q Yan, Z Tothova, K Yamane, H Erdjument-Bromage, P Tempst, ... Cell 128 (5), 889-900, 2007 | 504 | 2007 |
| Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA M Wang, C Mao, L Ouyang, Y Liu, W Lai, N Liu, Y Shi, L Chen, D Xiao, ... Cell Death & Differentiation 26 (11), 2329-2343, 2019 | 429 | 2019 |
| Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer J Cao, Q Yan Frontiers in oncology 2, 26, 2012 | 374 | 2012 |
| The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2 T Kamura, MN Conrad, Q Yan, RC Conaway, JW Conaway Genes & development 13 (22), 2928-2933, 1999 | 349 | 1999 |
| Immunological differences between primary and metastatic breast cancer B Szekely, V Bossuyt, X Li, VB Wali, GA Patwardhan, C Frederick, A Silber, ... Annals of Oncology 29 (11), 2232-2239, 2018 | 283 | 2018 |
| An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting J Cao, L Wu, SM Zhang, M Lu, WKC Cheung, W Cai, M Gale, Q Xu, Q Yan Nucleic acids research 44 (19), e149-e149, 2016 | 247 | 2016 |
| The Hypoxia-Inducible Factor 2α N-Terminal and C-Terminal Transactivation Domains Cooperate To Promote Renal Tumorigenesis In Vivo Q Yan, S Bartz, M Mao, L Li, WG Kaelin Jr Molecular and cellular biology 27 (6), 2092-2102, 2007 | 237 | 2007 |
| EGLN1/c-Myc induced lymphoid-specific helicase inhibits ferroptosis through lipid metabolic gene expression changes Y Jiang, C Mao, R Yang, B Yan, Y Shi, X Liu, W Lai, Y Liu, X Wang, ... Theranostics 7 (13), 3293, 2017 | 228 | 2017 |
| pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-κB agonist Card9 by CK2 H Yang, YA Minamishima, Q Yan, S Schlisio, BL Ebert, X Zhang, L Zhang, ... Molecular cell 28 (1), 15-27, 2007 | 219 | 2007 |
| Cancer epigenetics, tumor immunity, and immunotherapy J Cao, Q Yan Trends in cancer 6 (7), 580-592, 2020 | 217 | 2020 |
| Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase T Kamura, D Burian, Q Yan, SL Schmidt, WS Lane, E Querido, PE Branton, ... Journal of Biological Chemistry 276 (32), 29748-29753, 2001 | 186 | 2001 |
| Epigenetic regulation by lysine demethylase 5 (KDM5) enzymes in cancer LP Blair, J Cao, MR Zou, J Sayegh, Q Yan Cancers 3 (1), 1383-1404, 2011 | 179 | 2011 |
| The von Hippel–Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C X Niu, T Zhang, L Liao, L Zhou, DJ Lindner, M Zhou, B Rini, Q Yan, ... Oncogene 31 (6), 776-786, 2012 | 168 | 2012 |
| Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1 W Lin, J Cao, J Liu, ML Beshiri, Y Fujiwara, J Francis, AD Cherniack, ... Proceedings of the National Academy of Sciences 108 (33), 13379-13386, 2011 | 161 | 2011 |
| KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements SM Zhang, WL Cai, X Liu, D Thakral, J Luo, LH Chan, MK McGeary, ... Nature 598 (7882), 682-687, 2021 | 157 | 2021 |
| Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis YC Teng, CF Lee, YS Li, YR Chen, PW Hsiao, MY Chan, FM Lin, ... Cancer research 73 (15), 4711-4721, 2013 | 153 | 2013 |
| Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen J Sayegh, J Cao, MR Zou, A Morales, LP Blair, M Norcia, D Hoyer, ... Journal of Biological Chemistry 288 (13), 9408-9417, 2013 | 152 | 2013 |
| Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53 P Blanchette, CY Cheng, Q Yan, G Ketner, DA Ornelles, T Dobner, ... Molecular and cellular biology 24 (21), 9619-9629, 2004 | 149 | 2004 |
Jian CaoRutgers Cancer Institute of New JerseyVerified email at rutgers.edu
