Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome HJ Hwang, P Dornbos, M Steidemann, TK Dunivin, M Rizzo, JJ LaPres Toxicology and Applied Pharmacology 304, 121-132, 2016 | 79 | 2016 |
Dose-dependent metabolic reprogramming and differential gene expression in TCDD-elicited hepatic fibrosis R Nault, KA Fader, DA Ammendolia, P Dornbos, D Potter, B Sharratt, ... Toxicological Sciences 154 (2), 253-266, 2016 | 70 | 2016 |
Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes JK Goodrich, M Singer-Berk, R Son, A Sveden, J Wood, E England, ... Nature communications 12 (1), 3505, 2021 | 59 | 2021 |
The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits MC Costanzo, M von Grotthuss, J Massung, D Jang, L Caulkins, ... Cell metabolism 35 (4), 695-710. e6, 2023 | 37 | 2023 |
Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes G Hindy, P Dornbos, MD Chaffin, DJ Liu, M Wang, MS Selvaraj, D Zhang, ... The American Journal of Human Genetics 109 (1), 81-96, 2022 | 27 | 2022 |
Mercury exposure and neurochemical biomarkers in multiple brain regions of Wisconsin River Otters (Lontra canadensis) P Dornbos, S Strom, N Basu Ecotoxicology 22, 469-475, 2013 | 26 | 2013 |
Incorporating population-level genetic variability within laboratory models in toxicology: from the individual to the population P Dornbos, JJ LaPres Toxicology 395, 1-8, 2018 | 25 | 2018 |
A combined polygenic score of 21,293 rare and 22 common variants improves diabetes diagnosis based on hemoglobin A1C levels P Dornbos, R Koesterer, A Ruttenburg, T Nguyen, JB Cole, ... Nature genetics 54 (11), 1609-1614, 2022 | 23 | 2022 |
Rare loss of function variants in the hepatokine gene INHBE protect from abdominal obesity AM Deaton, A Dubey, LD Ward, P Dornbos, J Flannick, ... Nature Communications 13 (1), 4319, 2022 | 20 | 2022 |
The Influence of Human Interindividual Variability on the Low-Dose Region of Dose-Response Curve Induced by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Primary B … P Dornbos, RB Crawford, NE Kaminski, SL Hession, JJ LaPres Toxicological Sciences 153 (2), 352-360, 2016 | 18 | 2016 |
Hepatic polybrominated diphenyl ether (PBDE) levels in Wisconsin river otters (Lontra canadensis) and Michigan bald eagles (Haliaeetus leucocephalus) P Dornbos, S Chernyak, J Rutkiewicz, T Cooley, S Strom, S Batterman, ... Journal of Great Lakes Research 41 (1), 222-227, 2015 | 17 | 2015 |
Evaluating human genetic support for hypothesized metabolic disease genes P Dornbos, P Singh, DK Jang, A Mahajan, SB Biddinger, JI Rotter, ... Cell metabolism 34 (5), 661-666, 2022 | 15 | 2022 |
Characterizing the role of HMG-CoA reductase in aryl hydrocarbon receptor-mediated liver injury in C57BL/6 mice P Dornbos, A Jurgelewicz, KA Fader, K Williams, TR Zacharewski, ... Scientific reports 9 (1), 15828, 2019 | 15 | 2019 |
A cell‐free testing platform to screen chemicals of potential neurotoxic concern across twenty vertebrate species A Arini, K Mittal, P Dornbos, J Head, J Rutkiewicz, N Basu Environmental toxicology and chemistry 36 (11), 3081-3090, 2017 | 12 | 2017 |
Characterizing Serpinb2 as a Modulator of TCDD-Induced Suppression of the B Cell P Dornbos, M Warren, RB Crawford, NE Kaminski, DW Threadgill, ... Chemical research in toxicology 31 (11), 1248-1259, 2018 | 10 | 2018 |
Loss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In Mice Y Saini, SP Proper, P Dornbos, KK Greenwood, AK Kopec, SG Lynn, ... PLoS One 10 (9), e0139270, 2015 | 8 | 2015 |
The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes A Huerta-Chagoya, P Schroeder, R Mandla, AJ Deutsch, W Zhu, L Petty, ... Diabetologia 66 (7), 1273-1288, 2023 | 7 | 2023 |
Genetics-based approach to identify novel genes regulated by the aryl hydrocarbon receptor in mouse liver A Jurgelewicz, P Dornbos, M Warren, R Nault, A Arkatkar, H Lin, ... Toxicological Sciences 181 (2), 285-294, 2021 | 5 | 2021 |
AHR-dependent changes in the mitochondrial proteome in response to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin HJ Hwang, P Dornbos, JJ LaPres Data in brief 8, 191-195, 2016 | 3 | 2016 |
A combined polygenic score of 21,293 rare and 22 common variants significantly improves diabetes diagnosis based on hemoglobin A1C levels P Dornbos, R Koesterer, A Ruttenburg, JB Cole, ... medRxiv, 2021.11. 04.21265868, 2021 | 2 | 2021 |