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Richard Apodaca
Richard Apodaca
Metamolecular, LLC
Verified email at metamolecular.com - Homepage
Title
Cited by
Cited by
Year
Direct reductive amination of aldehydes and ketones using phenylsilane: catalysis by dibutyltin dichloride
R Apodaca, W Xiao
Organic letters 3 (11), 1745-1748, 2001
2012001
Acute wake‐promoting actions of JNJ‐5207852, a novel, diamine‐based H3 antagonist
AJ Barbier, C Berridge, C Dugovic, AD Laposky, SJ Wilson, J Boggs, ...
British journal of pharmacology 143 (5), 649-661, 2004
1962004
A new class of diamine-based human histamine H3 receptor antagonists: 4-(aminoalkoxy) benzylamines
R Apodaca, CA Dvorak, W Xiao, AJ Barbier, JD Boggs, SJ Wilson, ...
Journal of medicinal chemistry 46 (18), 3938-3944, 2003
1402003
Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase
JM Keith, R Apodaca, W Xiao, M Seierstad, K Pattabiraman, J Wu, ...
Bioorganic & medicinal chemistry letters 18 (17), 4838-4843, 2008
1012008
Potent and selective α-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase
FA Romero, W Du, I Hwang, TJ Rayl, FS Kimball, D Leung, HS Hoover, ...
Journal of medicinal chemistry 50 (5), 1058-1068, 2007
902007
Biochemical and biological properties of 4-(3-phenyl-[1, 2, 4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase
MJ Karbarz, L Luo, L Chang, CS Tham, JA Palmer, SJ Wilson, ...
Anesthesia & Analgesia 108 (1), 316-329, 2009
822009
4-Phenoxypiperidines:  Potent, Conformationally Restricted, Non-Imidazole Histamine H3 Antagonists
CA Dvorak, R Apodaca, AJ Barbier, CW Berridge, SJ Wilson, JD Boggs, ...
Journal of medicinal chemistry 48 (6), 2229-2238, 2005
812005
Lead identification of acetylcholinesterase inhibitors–histamine H3 receptor antagonists from molecular modeling
SD Bembenek, JM Keith, MA Letavic, R Apodaca, AJ Barbier, L Dvorak, ...
Bioorganic & medicinal chemistry 16 (6), 2968-2973, 2008
762008
N-heteroarylpiperazinyl ureas as modulators of fatty acid amide hydrolase
R Apodaca, JG Breitenbucher, K Pattabiraman, M Seierstad, W Xiao
US Patent 7,541,359, 2009
66*2009
Trimethylsilylcyanation of aldehydes and ketones catalyzed by diorganotin dichlorides
JK Whitesell, R Apodaca
Tetrahedron letters 37 (15), 2525-2528, 1996
661996
Aryl piperazinyl ureas as inhibitors of fatty acid amide hydrolase (FAAH) in rat, dog, and primate
JM Keith, R Apodaca, M Tichenor, W Xiao, W Jones, J Pierce, M Seierstad, ...
ACS medicinal chemistry letters 3 (10), 823-827, 2012
432012
Aplysamine-1 and related analogs as histamine H3 receptor antagonists
DM Swanson, SJ Wilson, JD Boggs, W Xiao, R Apodaca, AJ Barbier, ...
Bioorganic & medicinal chemistry letters 16 (4), 897-900, 2006
372006
Novel ketooxazole based inhibitors of fatty acid amide hydrolase (FAAH)
A Timmons, M Seierstad, R Apodaca, M Epperson, D Pippel, S Brown, ...
Bioorganic & medicinal chemistry letters 18 (6), 2109-2113, 2008
322008
Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists
DM Swanson, CR Shah, B Lord, K Morton, LK Dvorak, C Mazur, ...
European journal of medicinal chemistry 44 (11), 4413-4425, 2009
292009
Non-imidazole aryloxypiperidines
R Apodaca, NI Carruthers, CA Dvorak, CR Shah, W Xiao
US Patent 7,071,191, 2006
242006
A convenient synthesis of protected and free homoallylic alcohols: Catalytic use of dibutyltin dichloride in the allylation of aldehydes with allyltributyltin
JK Whitesell, R Apodaca
Tetrahedron letters 37 (23), 3955-3958, 1996
221996
Piperazinyl and diazapanyl benzamides and benzthioamides
RL Apodaca, JA Jablonowski, KS Ly, CR Shah, DM Swanson, W Xiao
US Patent 7,414,047, 2008
212008
2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase
R Apodaca, JG Breitenbucher, MT Epperson, AK Fried, DJ Pippel, ...
US Patent App. 12/094,139, 2009
20*2009
Novel benzamide-based histamine H3 receptor antagonists: the identification of two candidates for clinical development
MA Letavic, L Aluisio, R Apodaca, M Bajpai, AJ Barbier, A Bonneville, ...
ACS Medicinal Chemistry Letters 6 (4), 450-454, 2015
192015
Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase
R Apodaca, JG Breitenbucher, AL Chambers, X Deng, NA Hawryluk, ...
US Patent 8,598,202, 2013
182013
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