Redox-based reagents for chemoselective methionine bioconjugation S Lin, X Yang, S Jia, AM Weeks, M Hornsby, PS Lee, RV Nichiporuk, ... Science 355 (6325), 597-602, 2017 | 428 | 2017 |
Engineering peptide ligase specificity by proteomic identification of ligation sites AM Weeks, JA Wells Nature chemical biology 14 (1), 50-57, 2018 | 100 | 2018 |
Subtiligase-catalyzed peptide ligation AM Weeks, JA Wells Chemical reviews 120 (6), 3127-3160, 2019 | 90 | 2019 |
Constructing de novo biosynthetic pathways for chemical synthesis inside living cells AM Weeks, MCY Chang Biochemistry 50 (24), 5404-5418, 2011 | 50 | 2011 |
Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity AM Weeks, SM Coyle, M Jinek, JA Doudna, MCY Chang Biochemistry 49 (43), 9269-9279, 2010 | 36 | 2010 |
Mapping proteolytic neo-N termini at the surface of living cells AM Weeks, JR Byrnes, I Lui, JA Wells Proceedings of the National Academy of Sciences 118 (8), e2018809118, 2021 | 34 | 2021 |
Biochemical and Structural Characterization of the trans-Enoyl-CoA Reductase from Treponema denticola BB Bond-Watts, AM Weeks, MCY Chang Biochemistry 51 (34), 6827-6837, 2012 | 30 | 2012 |
Catalytic control of enzymatic fluorine specificity AM Weeks, MCY Chang Proceedings of the National Academy of Sciences 109 (48), 19667-19672, 2012 | 26 | 2012 |
Temporal and fluoride control of secondary metabolism regulates cellular organofluorine biosynthesis MC Walker, M Wen, AM Weeks, MCY Chang ACS chemical biology 7 (9), 1576-1585, 2012 | 21 | 2012 |
Molecular recognition of fluorine impacts substrate selectivity in the fluoroacetyl-CoA thioesterase FlK AM Weeks, NS Keddie, RDP Wadoux, D O’Hagan, MCY Chang Biochemistry 53 (12), 2053-2063, 2014 | 19 | 2014 |
N‐Terminal Modification of Proteins with Subtiligase Specificity Variants AM Weeks, JA Wells Current Protocols in Chemical Biology 12 (1), e79, 2020 | 16 | 2020 |
Entropy drives selective fluorine recognition in the fluoroacetyl–CoA thioesterase from Streptomyces cattleya AM Weeks, N Wang, JG Pelton, MCY Chang Proceedings of the National Academy of Sciences 115 (10), E2193-E2201, 2018 | 13 | 2018 |
Protein engineering for selective proteomics K Radziwon, AM Weeks Current Opinion in Chemical Biology 60, 10-19, 2021 | 10 | 2021 |
Direct identification of proteolytic cleavages on living cells using a glycan-tethered peptide ligase K Schaefer, I Lui, JR Byrnes, E Kang, J Zhou, AM Weeks, JA Wells ACS central science 8 (10), 1447-1456, 2022 | 9 | 2022 |
Hypoxia is a dominant remodeler of the effector T cell surface proteome relative to activation and regulatory T cell suppression JR Byrnes, AM Weeks, E Shifrut, J Carnevale, L Kirkemo, A Ashworth, ... Molecular & Cellular Proteomics 21 (4), 2022 | 9 | 2022 |
Engineered peptide ligases for cell signaling and bioconjugation CL Frazier, AM Weeks Biochemical Society Transactions 48 (3), 1153-1165, 2020 | 7 | 2020 |
Kinases leave their mark on caspase substrates AM Weeks Biochemical Journal 478 (17), 3179-3184, 2021 | 3 | 2021 |
An N terminomics toolbox combining 2-pyridinecarboxaldehyde probes and click chemistry for profiling protease specificity HN Bridge, W Leiter, CL Frazier, AM Weeks Cell Chemical Biology 31 (3), 534-549. e8, 2024 | 2 | 2024 |
An expanded 2-pyridinecarboxaldehyde (2PCA)-based chemoproteomics toolbox for probing protease specificity HN Bridge, CL Frazier, AM Weeks BioRxiv, 2023.02. 12.528234, 2023 | 2 | 2023 |
Voices of chemical biology B Davis, K Backus, G Winter, R Chica, D Li, SY Lee, C He, A Weeks, ... Nature Chemical Biology 17 (1), 1-4, 2021 | 2 | 2021 |