| Protein tyrosine phosphatases as potential therapeutic targets R He, Z Yu, R Zhang, Z Zhang Acta pharmacologica sinica 35 (10), 1227-1246, 2014 | 351 | 2014 |
| Phosphonium Salts as Chiral Phase‐Transfer Catalysts: Asymmetric Michael and Mannich Reactions of 3‐Aryloxindoles R He, C Ding, K Maruoka Angewandte Chemie International Edition 48 (25), 4559-4561, 2009 | 287 | 2009 |
| Enantioselective base-free phase-transfer reaction in water-rich solvent R He, S Shirakawa, K Maruoka Journal of the American Chemical Society 131 (46), 16620-16621, 2009 | 229 | 2009 |
| Binaphthyl‐Modified Quaternary Phosphonium Salts as Chiral Phase‐Transfer Catalysts: Asymmetric Amination of β‐Keto Esters R He, X Wang, T Hashimoto, K Maruoka Angewandte Chemie International Edition 47 (49), 9466-9468, 2008 | 227 | 2008 |
| Small molecule tools for functional interrogation of protein tyrosine phosphatases R He, LF Zeng, Y He, S Zhang, ZY Zhang The FEBS journal 280 (2), 731-750, 2013 | 150 | 2013 |
| Peptide conjugates with small molecules designed to enhance efficacy and safety R He, B Finan, JP Mayer, RD DiMarchi Molecules 24 (10), 1855, 2019 | 102 | 2019 |
| Diastereo-and enantioselective conjugate addition of α-substituted nitroacetates to maleimides under base-free neutral phase-transfer conditions S Shirakawa, SJ Terao, R He, K Maruoka Chemical communications 47 (38), 10557-10559, 2011 | 80 | 2011 |
| Polymer‐Supported Hantzsch 1, 4‐Dihydropyridine Ester: An Efficient Biomimetic Hydrogen Source R He, PH Toy, Y Lam Advanced Synthesis & Catalysis 350 (1), 54-60, 2008 | 62 | 2008 |
| Exploring the existing drug space for novel pTyr mimetic and SHP2 inhibitors R He, ZH Yu, RY Zhang, L Wu, AM Gunawan, BS Lane, JS Shim, LF Zeng, ... ACS medicinal chemistry letters 6 (7), 782-786, 2015 | 57 | 2015 |
| Highly efficient asymmetric amination of β-keto esters catalyzed by chiral quaternary ammonium bromides Q Lan, X Wang, R He, C Ding, K Maruoka Tetrahedron Letters 50 (26), 3280-3282, 2009 | 54 | 2009 |
| Mycobacterial protein tyrosine phosphatases A and B inhibitors augment the bactericidal activity of the standard anti-tuberculosis regimen NK Dutta, R He, ML Pinn, Y He, F Burrows, ZY Zhang, PC Karakousis ACS infectious diseases 2 (3), 231-239, 2016 | 46 | 2016 |
| Binaphthyl-modified quaternary phosphonium salts as chiral phase transfer catalysts: Application to asymmetric amination of β-Keto esters R He, K Maruoka Synthesis 2009 (13), 2289-2292, 2009 | 43 | 2009 |
| A Base‐Free Neutral Phase‐Transfer Reaction System S Shirakawa, L Wang, R He, S Arimitsu, K Maruoka Chemistry–An Asian Journal 9 (6), 1586-1593, 2014 | 40 | 2014 |
| Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors Y He, LF Zeng, ZH Yu, R He, S Liu, ZY Zhang Bioorganic & medicinal chemistry 20 (6), 1940-1946, 2012 | 40 | 2012 |
| Traceless solid-phase synthesis of substituted xanthines R He, SM Ching, Y Lam Journal of Combinatorial Chemistry 8 (6), 923-928, 2006 | 35 | 2006 |
| Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitor R He, Z Yu, Y He, LF Zeng, J Xu, L Wu, AM Gunawan, L Wang, ZX Jiang, ... ChemMedChem 5 (12), 2051-2056, 2010 | 30 | 2010 |
| Stepwise construction of disulfides in peptides R He, J Pan, JP Mayer, F Liu ChemBioChem 21 (8), 1101-1111, 2020 | 29 | 2020 |
| A Facile Hydroxyindole Carboxylic Acid Based Focused Library Approach for Potent and Selective Inhibitors of Mycobacterium Protein Tyrosine Phosphatase B LF Zeng, J Xu, Y He, R He, L Wu, AM Gunawan, ZY Zhang ChemMedChem 8 (6), 904-908, 2013 | 29 | 2013 |
| CB1 and GLP-1 receptors cross talk provides new therapies for obesity P Zizzari, R He, S Falk, L Bellocchio, C Allard, S Clark, T Lesté-Lasserre, ... Diabetes 70 (2), 415-422, 2021 | 27 | 2021 |
| Organocatalytic multicomponent reaction for the acquisition of a selective inhibitor of mPTPB, a virulence factor of tuberculosis R He, LF Zeng, Y He, L Wu, AM Gunawan, ZY Zhang Chemical communications 49 (20), 2064-2066, 2013 | 27 | 2013 |
