DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations. EF Fynan, RG Webster, DH Fuller, JR Haynes, JC Santoro, HL Robinson Proceedings of the National Academy of Sciences 90 (24), 11478-11482, 1993 | 1787 | 1993 |
Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine MJ Roy, MS Wu, LJ Barr, JT Fuller, LG Tussey, S Speller, J Culp, ... Vaccine 19 (7-8), 764-778, 2000 | 500 | 2000 |
Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2 AC Walls, B Fiala, A Schäfer, S Wrenn, MN Pham, M Murphy, ... Cell 183 (5), 1367-1382. e17, 2020 | 446 | 2020 |
Massively parallel de novo protein design for targeted therapeutics A Chevalier, DA Silva, GJ Rocklin, DR Hicks, R Vergara, P Murapa, ... Nature 550 (7674), 74-79, 2017 | 417 | 2017 |
Gene gun-based nucleic acid immunization: elicitation of humoral and cytotoxic T lymphocyte responses following epidermal delivery of nanogram quantities of DNA TM Pertmer, MD Eisenbraun, D McCabe, SK Prayaga, DH Fuller, ... Vaccine 13 (15), 1427-1430, 1995 | 392 | 1995 |
Examination of parameters affecting the elicitation of humoral immune responses by particle bombardment-mediated genetic immunization MD Eisenbraun, DH FULLER, JR HAYNES DNA and cell biology 12 (9), 791-797, 1993 | 328 | 1993 |
Induction of AIDS virus-specific CTL activity in fresh, unstimulated peripheral blood lymphocytes from rhesus macaques vaccinated with a DNA prime/modified vaccinia virus … TM Allen, TU Vogel, DH Fuller, BR Mothe, S Steffen, JE Boyson, T Shipley, ... The Journal of Immunology 164 (9), 4968-4978, 2000 | 311 | 2000 |
Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and … H Horton, TU Vogel, DK Carter, K Vielhuber, DH Fuller, T Shipley, ... Journal of virology 76 (14), 7187-7202, 2002 | 235 | 2002 |
DNA vaccines expressing either the GP or NP genes of Ebola virus protect mice from lethal challenge L Vanderzanden, M Bray, D Fuller, T Roberts, D Custer, K Spik, P Jahrling, ... Virology 246 (1), 134-144, 1998 | 225 | 1998 |
An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates JH Erasmus, AP Khandhar, MA O’Connor, AC Walls, EA Hemann, ... Science translational medicine 12 (555), eabc9396, 2020 | 207 | 2020 |
Preclinical and clinical progress of particle-mediated DNA vaccines for infectious diseases DH Fuller, P Loudon, C Schmaljohn Methods 40 (1), 86-97, 2006 | 200 | 2006 |
Vaccination with HIV-1 gp120 DNA induces immune responses that are boosted by a recombinant gp120 protein subunit SW Barnett, S Rajasekar, H Legg, B Doe, DH Fuller, JR Haynes, ... Vaccine 15 (8), 869-873, 1997 | 198 | 1997 |
A qualitative progression in HIV type 1 glycoprotein 120-specific cytotoxic cellular and humoral immune responses in mice receiving a DNA-based glycoprotein 120 vaccine DH Fuller, JR Haynes AIDS research and human retroviruses 10 (11), 1433-1441, 1994 | 189 | 1994 |
Use of DNAs expressing HIV-1 Env and noninfectious HIV-1 particles to raise antibody responses in mice S Lu, JC Santoro, DH Fuller, JR Haynes, HL Robinson Virology 209 (1), 147-154, 1995 | 187 | 1995 |
De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2 TW Linsky, R Vergara, N Codina, JW Nelson, MJ Walker, W Su, ... Science 370 (6521), 1208-1214, 2020 | 183 | 2020 |
Induction of mucosal protection against primary, heterologous simian immunodeficiency virus by a DNA vaccine DH Fuller, PA Rajakumar, LA Wilson, AM Trichel, JT Fuller, T Shipley, ... Journal of virology 76 (7), 3309-3317, 2002 | 145 | 2002 |
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines AC Walls, MC Miranda, A Schäfer, MN Pham, A Greaney, ... Cell 184 (21), 5432-5447. e16, 2021 | 142 | 2021 |
Enhancement of immunodeficiency virus-specific immune responses in DNA-immunized rhesus macaques DH Fuller, MM Corb, S Barnett, K Steimer, JR Haynes Vaccine 15 (8), 924-926, 1997 | 137 | 1997 |
Multispecific Vaccine-Induced Mucosal Cytotoxic TLymphocytes Reduce Acute-Phase Viral Replication but Fail inLong-Term Control of Simian Immunodeficiency VirusSIVmac239 TU Vogel, MR Reynolds, DH Fuller, K Vielhuber, T Shipley, JT Fuller, ... Journal of virology 77 (24), 13348-13360, 2003 | 128 | 2003 |
Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site EM Strauch, SM Bernard, D La, AJ Bohn, PS Lee, CE Anderson, ... Nature biotechnology 35 (7), 667-671, 2017 | 127 | 2017 |