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Osama Saher
Osama Saher
Present : Karolinska institute ; Past: Faculty of Pharmacy, Cairo university
Verified email at ki.se
Title
Cited by
Cited by
Year
The viral protein corona directs viral pathogenesis and amyloid aggregation
K Ezzat, M Pernemalm, S Pålsson, TC Roberts, P Järver, A Dondalska, ...
Nature communications 10 (1), 2331, 2019
1812019
Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging
D Gupta, X Liang, S Pavlova, OPB Wiklander, G Corso, Y Zhao, O Saher, ...
Journal of extracellular vesicles 9 (1), 1800222, 2020
1262020
Growth media conditions influence the secretion route and release levels of engineered extracellular vesicles
JP Bost, O Saher, D Hagey, DR Mamand, X Liang, W Zheng, G Corso, ...
Advanced healthcare materials 11 (5), 2101658, 2022
402022
Preparation and in vitro/in vivo evaluation of antimicrobial ocular in situ gels containing a disappearing preservative for topical treatment of bacterial conjunctivitis
O Saher, DM Ghorab, NM Mursi
Pharmaceutical development and technology 21 (5), 600-610, 2016
282016
Levofloxacin hemihydrate ocular semi-sponges for topical treatment of bacterial conjunctivitis: Formulation and in-vitro/in-vivo characterization
O Saher, DM Ghorab, NM Mursi
Journal of Drug Delivery Science and Technology 31, 22-34, 2016
252016
Novel mouse model resistant to irreversible BTK inhibitors: a tool identifying new therapeutic targets and side effects
HY Estupiñán, T Bouderlique, C He, A Berglöf, D Gupta, O Saher, ...
Blood Advances 4 (11), 2439-2450, 2020
222020
Novel peptide-dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice-switching activity
O Saher, CSJ Rocha, EM Zaghloul, OPB Wiklander, S Zamolo, M Heitz, ...
European Journal of Pharmaceutics and Biopharmaceutics 132, 29-40, 2018
212018
Sugar and polymer excipients enhance uptake and splice-switching activity of peptide-dendrimer/lipid/oligonucleotide formulations
O Saher, T Lehto, O Gissberg, D Gupta, O Gustafsson, SEL Andaloussi, ...
Pharmaceutics 11 (12), 666, 2019
112019
Oligonucleotide–Palladacycle conjugates as splice-correcting agents
M Hande, O Saher, KE Lundin, CIE Smith, R Zain, T Lönnberg
Molecules 24 (6), 1180, 2019
112019
The cellular response to extracellular vesicles is dependent on their cell source and dose
DW Hagey, M Ojansivu, BR Bostancioglu, O Saher, JP Bost, ...
Science advances 9 (35), eadh1168, 2023
102023
Novel endosomolytic compounds enable highly potent delivery of antisense oligonucleotides
JP Bost, M Ojansivu, MJ Munson, E Wesén, A Gallud, D Gupta, ...
Communications Biology 5 (1), 185, 2022
72022
Lipophilic peptide dendrimers for delivery of splice-switching oligonucleotides
H Daralnakhla, O Saher, S Zamolo, S Bazaz, J P. Bost, M Heitz, ...
Pharmaceutics 13 (1), 116, 2021
72021
Oligonucleotides Targeting DNA Repeats Downregulate Huntingtin Gene Expression in Huntington's Patient-Derived Neural Model System
T Umek, T Olsson, O Gissberg, O Saher, EM Zaghloul, KE Lundin, ...
nucleic acid therapeutics 31 (6), 443-456, 2021
62021
Novel orthogonally hydrocarbon-modified cell-penetrating peptide nanoparticles mediate efficient delivery of splice-switching antisense oligonucleotides in vitro and in vivo
S Bazaz, T Lehto, R Tops, O Gissberg, D Gupta, B Bestas, J Bost, ...
Biomedicines 9 (8), 1046, 2021
62021
The viral protein corona directs viral pathogenesis and amyloid aggregation, Nat. Commun. 10 (2019) 2331
K Ezzat, M Pernemalm, S Palsson, TC Roberts, P Jarver, A Dondalska, ...
5
Chemical Modifications and Design Influence the Potency of Huntingtin Anti-Gene Oligonucleotides
O Saher, EM Zaghloul, T Umek, DW Hagey, N Mozafari, MB Danielsen, ...
nucleic acid therapeutics 33 (2), 117-131, 2023
22023
Tumor cell derived osteopontin and prostaglandin E2 synergistically promote the expansion of myeloid derived suppressor cells during the tumor immune escape phase
DR Mamand, S Bazaz, DK Mohammad, O Saher, OPB Wiklander, ...
International Immunopharmacology 129, 111584, 2024
2024
Anti-gene oligonucleotides targeting Friedreichs ataxia expanded GAA: TTC repeats increase Frataxin expression
N Mozafari, SIM Milagres, CSJ Rocha, CM Vargiu, F Freyberger, O Saher, ...
bioRxiv, 2024.01. 25.577034, 2024
2024
Pharmaceutical Insights into Improving Oligonucleotide Delivery and Efficacy
O Saher
PQDT-Global, 2021
2021
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Articles 1–19