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Laetitia Gaspar
Laetitia Gaspar
PhD, Researcher at the Center for Neuroscience and Cell Biology, University of Coimbra
Email confirmado em cnc.uc.pt
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Obstructive sleep apnea and hallmarks of aging
LS Gaspar, AR Álvaro, J Moita, C Cavadas
Trends in molecular medicine 23 (8), 675-692, 2017
732017
The importance of determining circadian parameters in pharmacological studies
LS Gaspar, AR Álvaro, S Carmo‐Silva, AF Mendes, A Relógio, ...
British journal of pharmacology 176 (16), 2827-2847, 2019
412019
Simple and Fast SEC-Based Protocol to Isolate Human Plasma-Derived Extracellular Vesicles for Transcriptional Research
LS Gaspar, MM Santana, C Henriques, MM Pinto, TM Ribeiro-Rodrigues, ...
Molecular Therapy-Methods & Clinical Development 18, 723-737, 2020
372020
Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea
LS Gaspar, J Hesse, M Yalçin, B Santos, C Carvalhas-Almeida, ...
EBioMedicine 65, 2021
232021
Trehalose alleviates the phenotype of Machado–Joseph disease mouse models
MM Santana, S Paixão, J Cunha-Santos, TP Silva, A Trevino-Garcia, ...
Journal of Translational Medicine 18, 1-17, 2020
222020
Peripheral biomarkers to diagnose obstructive sleep apnea in adults: A systematic review and meta-analysis
LS Gaspar, A Santos-Carvalho, B Santos, C Carvalhas-Almeida, ...
Sleep Medicine Reviews 64, 101659, 2022
162022
Common risk factors and therapeutic targets in obstructive sleep apnea and osteoarthritis: an unexpectable link?
LS Gaspar, C Sousa, AR Álvaro, C Cavadas, AF Mendes
Pharmacological Research 164, 105369, 2021
112021
Intermittent Hypoxia Alters the Circadian Expression of Clock Genes in Mouse Brain and Liver
BSC Koritala, YY Lee, SS Bhadri, LS Gaspar, C Stanforth, G Wu, ...
Genes 12 (10), 1627, 2021
82021
Obstructive sleep apnea in a mouse model is associated with tissue-specific transcriptomic changes in circadian rhythmicity and mean 24-hour gene expression
BSC Koritala, YY Lee, LS Gaspar, SS Bhadri, W Su, G Wu, LJ Francey, ...
PLoS biology 21 (5), e3002139, 2023
62023
A standardised protocol for blood and cerebrospinal fluid collection and processing for biomarker research in ataxia
MM Santana, LS Gaspar, MM Pinto, P Silva, D Adao, D Pereira, ...
Neuropathology and Applied Neurobiology 49 (2), e12892, 2023
12023
Murine Pro‐Inflammatory Responses to Acute and Sustained Intermittent Hypoxia: Implications for Obstructive Sleep Apnea Research
BSC Koritala, LS Gaspar, SS Bhadri, KS Massie, YY Lee, J Paulose, ...
The Laryngoscope 134, S1-S11, 2024
2024
Small non-coding RNA content in plasma-derived extracellular vesicles distinguish ataxic SCA3 mutation carriers from pre-ataxic and control subjects
MM Santana, P Silva, MM Pinto, L Gaspar, R Nobre, S Duarte, ...
2024
Small non-coding RNA content in plasma-derived extracellular vesicles distinguish ataxic SCA3 mutation carriers from pre-ataxic and control subjects
M Matos Santana, P Silva, MM Pinto, L Gaspar, RJ Nobre, S Duarte, ...
bioRxiv, 2024.01. 04.574044, 2024
2024
Systematic Review and Pathway Analysis of differentially expressed microRNAs in Obstructive Sleep Apnea
L Gaspar, A Capitão, B Santos, AF Mendes, C Cavadas, IS Moreira, ...
European Respiratory Journal 62 (suppl 67), 2023
2023
Isolation of Biologically Active Extracellular Vesicles-Associated AAVs for Gene Delivery to the Brain by Size Exclusion Chromatography
LP de Almeida, C Henriques, M Lopes, P Albuquerque, DR Ramos, ...
2023
Intermittent Hypoxia Alters Tissue-specific Circadian Transcriptome in a Mouse Model of Obstructive Sleep Apnea
BSC Koritala, YY Lee, L Gaspar, S Bhadri, G Wu, L Francey, M Ruben, ...
C69. PRECLINICAL COPD MODELS: IN VITRO, EX VIVO, IN VIVO, A5723-A5723, 2023
2023
Isolation of Biologically Active Extracellular Vesicles-Associated AAVs for Gene Delivery to the Brain by Size Exclusion Chromatography
C Henriques, MM Lopes, P Albuquerque, D Rufino-Ramos, LS Gaspar, ...
bioRxiv, 2023.05. 30.542901, 2023
2023
THE SUPERPOWERS OF OUR SLEEP
LS Gaspar, B Santos, AT Barros-Viegas, J Cardoso, SV Amaral, ...
YOU SNOOZE, YOU DON’T LOSE-WHAT IS SLEEP AND WHY IS IT SO CRUCIAL?, 10, 2022
2022
Production and isolation of natural and biologically active exo-AAvs for brain gene delivery
C Henriques, M Lopes, P Albuquerque, D Rufino-Ramos, L Gaspar, ...
HUMAN GENE THERAPY 33 (23-24), A47-A47, 2022
2022
The impact of obstructive sleep apnea treatment with continuous positive airway pressure on the biological clock
L Gaspar, J Hesse, M Yalçin, B Santos, C Carvalhas-Almeida, M Ferreira, ...
Sleep Medicine 100, S55-S56, 2022
2022
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