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Sarah DeVos
Sarah DeVos
Director & Principal Scientist, Denali Therapeutics
Verified email at dnli.com
Title
Cited by
Cited by
Year
Distinct tau prion strains propagate in cells and mice and define different tauopathies
DW Sanders, SK Kaufman, SL DeVos, AM Sharma, H Mirbaha, A Li, ...
Neuron 82 (6), 1271-1288, 2014
10122014
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
BB Holmes, SL DeVos, N Kfoury, M Li, R Jacks, K Yanamandra, ...
Proceedings of the National Academy of Sciences 110 (33), E3138-E3147, 2013
8552013
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy
SL DeVos, RL Miller, KM Schoch, BB Holmes, CS Kebodeaux, ...
Science translational medicine 9 (374), eaag0481, 2017
4272017
Tau protein disrupts nucleocytoplasmic transport in Alzheimer’s disease
B Eftekharzadeh, JG Daigle, LE Kapinos, A Coyne, J Schiantarelli, ...
Neuron 99 (5), 925-940. e7, 2018
3592018
Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain
S Takeda, S Wegmann, H Cho, SL DeVos, C Commins, AD Roe, ...
Nature communications 6 (1), 8490, 2015
3472015
Antisense reduction of tau in adult mice protects against seizures
SL DeVos, DK Goncharoff, G Chen, CS Kebodeaux, K Yamada, ...
Journal of Neuroscience 33 (31), 12887-12897, 2013
3352013
Synaptic tau seeding precedes tau pathology in human Alzheimer's disease brain
SL DeVos, BT Corjuc, DH Oakley, CK Nobuhara, RN Bannon, A Chase, ...
Frontiers in neuroscience 12, 267, 2018
2502018
The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer’s disease
SC Hopp, Y Lin, D Oakley, AD Roe, SL DeVos, D Hanlon, BT Hyman
Journal of neuroinflammation 15, 1-15, 2018
2402018
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys
MS Kariolis, RC Wells, JA Getz, W Kwan, CS Mahon, R Tong, DJ Kim, ...
Science translational medicine 12 (545), eaay1359, 2020
2142020
Enhanced tau aggregation in the presence of amyloid β
RE Bennett, SL DeVos, S Dujardin, B Corjuc, R Gor, J Gonzalez, AD Roe, ...
The American journal of pathology 187 (7), 1601-1612, 2017
2142017
Pathological correlations of [F‐18]‐AV‐1451 imaging in non‐alzheimer tauopathies
M Marquié, MD Normandin, AC Meltzer, M Siao Tick Chong, NV Andrea, ...
Annals of neurology 81 (1), 117-128, 2017
2042017
Increased 4R-tau induces pathological changes in a human-tau mouse model
KM Schoch, SL DeVos, RL Miller, SJ Chun, M Norrbom, DF Wozniak, ...
Neuron 90 (5), 941-947, 2016
1912016
Direct intraventricular delivery of drugs to the rodent central nervous system
SL DeVos, TM Miller
JoVE (Journal of Visualized Experiments), e50326, 2013
1902013
Antisense oligonucleotides: treating neurodegeneration at the level of RNA
SL DeVos, TM Miller
Neurotherapeutics 10 (3), 486-497, 2013
1752013
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity
S Wegmann, EA Maury, MJ Kirk, L Saqran, A Roe, SL DeVos, S Nicholls, ...
The EMBO journal 34 (24), 3028-3041, 2015
1202015
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
T Logan, MJ Simon, A Rana, GM Cherf, A Srivastava, SS Davis, RLY Low, ...
Cell 184 (18), 4651-4668. e25, 2021
1092021
Seed‐competent high‐molecular‐weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients
S Takeda, C Commins, SL DeVos, CK Nobuhara, S Wegmann, AD Roe, ...
Annals of neurology 80 (3), 355-367, 2016
1052016
Tau antibody targeting pathological species blocks neuronal uptake and interneuron propagation of tau in vitro
CK Nobuhara, SL DeVos, C Commins, S Wegmann, BD Moore, AD Roe, ...
The American journal of pathology 187 (6), 1399-1412, 2017
1032017
Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo
SL DeVos, BT Corjuc, C Commins, S Dujardin, RN Bannon, D Corjuc, ...
Brain 141 (7), 2194-2212, 2018
932018
In vivo rate-determining steps of tau seed accumulation in Alzheimer’s disease
G Meisl, E Hidari, K Allinson, T Rittman, SL DeVos, JS Sanchez, CK Xu, ...
Science advances 7 (44), eabh1448, 2021
832021
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