Valerie M. Weaver
Valerie M. Weaver
Professor of Surgery, Anatomy, Bioengineering and Therapeutic Sciences, University of California
Verified email at ucsf.edu
TitleCited byYear
Tensional homeostasis and the malignant phenotype
MJ Paszek, N Zahir, KR Johnson, JN Lakins, GI Rozenberg, A Gefen, ...
Cancer cell 8 (3), 241-254, 2005
31592005
Matrix crosslinking forces tumor progression by enhancing integrin signaling
KR Levental, H Yu, L Kass, JN Lakins, M Egeblad, JT Erler, SFT Fong, ...
Cell 139 (5), 891-906, 2009
25632009
Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion
T Yeung, PC Georges, LA Flanagan, B Marg, M Ortiz, M Funaki, N Zahir, ...
Cell motility and the cytoskeleton 60 (1), 24-34, 2005
20422005
The extracellular matrix: a dynamic niche in cancer progression
P Lu, VM Weaver, Z Werb
J Cell Biol 196 (4), 395-406, 2012
18782012
The extracellular matrix at a glance
C Frantz, KM Stewart, VM Weaver
J Cell Sci 123 (24), 4195-4200, 2010
18292010
Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
VM Weaver, OW Petersen, F Wang, CA Larabell, P Briand, C Damsky, ...
The Journal of cell biology 137 (1), 231-245, 1997
14701997
A tense situation: forcing tumour progression
DT Butcher, T Alliston, VM Weaver
Nature Reviews Cancer 9 (2), 108, 2009
13252009
Extracellular matrix degradation and remodeling in development and disease
P Lu, K Takai, VM Weaver, Z Werb
Cold Spring Harbor perspectives in biology 3 (12), a005058, 2011
10012011
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival
BC Özdemir, T Pentcheva-Hoang, JL Carstens, X Zheng, CC Wu, ...
Cancer cell 25 (6), 719-734, 2014
9922014
β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
VM Weaver, S Lelièvre, JN Lakins, MA Chrenek, JCR Jones, F Giancotti, ...
Cancer cell 2 (3), 205-216, 2002
7642002
Mechanics, malignancy, and metastasis: the force journey of a tumor cell
S Kumar, VM Weaver
Cancer and Metastasis Reviews 28 (1-2), 113-127, 2009
7332009
Balancing forces: architectural control of mechanotransduction
CC DuFort, MJ Paszek, VM Weaver
Nature reviews Molecular cell biology 12 (5), 308, 2011
7172011
Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial …
F Wang, VM Weaver, OW Petersen, CA Larabell, S Dedhar, P Briand, ...
Proceedings of the National Academy of Sciences 95 (25), 14821-14826, 1998
6641998
The extracellular matrix modulates the hallmarks of cancer
MW Pickup, JK Mouw, VM Weaver
EMBO reports 15 (12), 1243-1253, 2014
6252014
The organizing principle: microenvironmental influences in the normal and malignant breast
MJ Bissell, DC Radisky, A Rizki, VM Weaver, OW Petersen
Differentiation: REVIEW 70 (9‐10), 537-546, 2002
5872002
Dynamic interplay between the collagen scaffold and tumor evolution
M Egeblad, MG Rasch, VM Weaver
Current opinion in cell biology 22 (5), 697-706, 2010
5582010
Extracellular matrix assembly: a multiscale deconstruction
JK Mouw, G Ou, VM Weaver
Nature reviews Molecular cell biology 15 (12), 771-785, 2014
5332014
The tension mounts: mechanics meets morphogenesis and malignancy
MJ Paszek, VM Weaver
Journal of mammary gland biology and neoplasia 9 (4), 325-342, 2004
4372004
Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth
MS Samuel, JI Lopez, EJ McGhee, DR Croft, D Strachan, P Timpson, ...
Cancer cell 19 (6), 776-791, 2011
3672011
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
MJ Paszek, CC DuFort, O Rossier, R Bainer, JK Mouw, K Godula, ...
Nature 511 (7509), 319, 2014
3312014
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