Camelid single domain antibodies (VHHs) as neuronal cell intrabody binding agents and inhibitors of Clostridium botulinum neurotoxin (BoNT) proteases JM Tremblay, CL Kuo, C Abeijon, J Sepulveda, G Oyler, X Hu, MM Jin, ... Toxicon 56 (6), 990-998, 2010 | 96 | 2010 |
Targeting botulinum neurotoxin persistence by the ubiquitin-proteasome system YC Tsai, R Maditz, C Kuo, PS Fishman, CB Shoemaker, GA Oyler, ... Proceedings of the National Academy of Sciences 107 (38), 16554-16559, 2010 | 95 | 2010 |
Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c CL Kuo, AL Goldberg Proceedings of the National Academy of Sciences 114 (17), E3404-E3413, 2017 | 70 | 2017 |
Accelerated neuronal cell recovery from Botulinum neurotoxin intoxication by targeted ubiquitination CL Kuo, GA Oyler, CB Shoemaker PLoS One 6 (5), e20352, 2011 | 55 | 2011 |
Subunit Oligomerization and Substrate Recognition of the Escherichia coli ClpYQ (HslUV) Protease Implicated by In Vivo Protein-Protein Interactions in the Yeast … YY Lee, CF Chang, CL Kuo, MC Chen, CH Yu, PI Lin, WF Wu Journal of Bacteriology 185 (8), 2393-2401, 2003 | 27 | 2003 |
Methods for the delivery of toxins or enzymatically active portions thereof GA Oyler, CB Shoemaker, C Kuo US Patent 8,492,109, 2013 | 20 | 2013 |
Lipid and cationic polymer based transduction of botulinum holotoxin, or toxin protease alone, extends the target cell range and improves the efficiency of intoxication CL Kuo, G Oyler, CB Shoemaker Toxicon 55 (2-3), 619-629, 2010 | 19 | 2010 |
Thiostrepton interacts covalently with Rpt subunits of the 19S proteasome and proteasome substrates C Sandu, N Chandramouli, JF Glickman, H Molina, CL Kuo, N Kukushkin, ... Journal of cellular and molecular medicine 19 (9), 2181-2192, 2015 | 16 | 2015 |
Methods to rapidly prepare mammalian 26S proteasomes for biochemical analysis CL Kuo, GA Collins, AL Goldberg The Ubiquitin Proteasome System: Methods and Protocols, 277-288, 2018 | 9 | 2018 |
Mammalian Ddi2 is a shuttling factor containing a retroviral protease domain that influences binding of ubiquitylated proteins and proteasomal degradation GA Collins, Z Sha, CL Kuo, B Erbil, AL Goldberg Journal of Biological Chemistry 298 (5), 2022 | 6 | 2022 |
Therapeutics which accelerate degradation BoNT/A LC within neurons GA Oyler, CL Kuo, J Sepulveda, YC Tsai, R Kincaid, S Tzipori, ... Toxicon 51, 17, 2008 | 5 | 2008 |
Methods for the delivery of toxins or enzymatically active portions thereof GA Oyler, CB Shoemaker, C Kuo US Patent App. 13/926,660, 2013 | 2 | 2013 |
Towards a molecular understanding of botulinum neurotoxin persistence GA Oyler, YC Tsai, C Kuo, C Shoemaker Toxicon, 67, 2013 | | 2013 |